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Items: 1 to 20 of 107

1.

The multifaceted therapeutic potential of benfotiamine.

Balakumar P, Rohilla A, Krishan P, Solairaj P, Thangathirupathi A.

Pharmacol Res. 2010 Jun;61(6):482-8. doi: 10.1016/j.phrs.2010.02.008. Epub 2010 Feb 25. Review.

PMID:
20188835
2.

Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy.

Hammes HP, Du X, Edelstein D, Taguchi T, Matsumura T, Ju Q, Lin J, Bierhaus A, Nawroth P, Hannak D, Neumaier M, Bergfeld R, Giardino I, Brownlee M.

Nat Med. 2003 Mar;9(3):294-9. Epub 2003 Feb 18.

PMID:
12592403
3.

Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives.

Volvert ML, Seyen S, Piette M, Evrard B, Gangolf M, Plumier JC, Bettendorff L.

BMC Pharmacol. 2008 Jun 12;8:10. doi: 10.1186/1471-2210-8-10.

4.

Effects of thiamine and benfotiamine on intracellular glucose metabolism and relevance in the prevention of diabetic complications.

Beltramo E, Berrone E, Tarallo S, Porta M.

Acta Diabetol. 2008 Sep;45(3):131-41. doi: 10.1007/s00592-008-0042-y. Epub 2008 Jun 26. Review.

PMID:
18581039
5.
6.

Benfotiamine prevents macro- and microvascular endothelial dysfunction and oxidative stress following a meal rich in advanced glycation end products in individuals with type 2 diabetes.

Stirban A, Negrean M, Stratmann B, Gawlowski T, Horstmann T, Götting C, Kleesiek K, Mueller-Roesel M, Koschinsky T, Uribarri J, Vlassara H, Tschoepe D.

Diabetes Care. 2006 Sep;29(9):2064-71.

PMID:
16936154
7.

Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats.

Stracke H, Hammes HP, Werkmann D, Mavrakis K, Bitsch I, Netzel M, Geyer J, Köpcke W, Sauerland C, Bretzel RG, Federlin KF.

Exp Clin Endocrinol Diabetes. 2001;109(6):330-6.

PMID:
11571671
8.

Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine.

Babaei-Jadidi R, Karachalias N, Ahmed N, Battah S, Thornalley PJ.

Diabetes. 2003 Aug;52(8):2110-20.

9.

Regulation of intracellular glucose and polyol pathway by thiamine and benfotiamine in vascular cells cultured in high glucose.

Berrone E, Beltramo E, Solimine C, Ape AU, Porta M.

J Biol Chem. 2006 Apr 7;281(14):9307-13. Epub 2006 Feb 1.

10.

High-dose thiamine therapy counters dyslipidemia and advanced glycation of plasma protein in streptozotocin-induced diabetic rats.

Karachalias N, Babaei-Jadidi R, Kupich C, Ahmed N, Thornalley PJ.

Ann N Y Acad Sci. 2005 Jun;1043:777-83.

PMID:
16037305
11.

Benfotiamine exhibits direct antioxidative capacity and prevents induction of DNA damage in vitro.

Schmid U, Stopper H, Heidland A, Schupp N.

Diabetes Metab Res Rev. 2008 Jul-Aug;24(5):371-7. doi: 10.1002/dmrr.860.

PMID:
18384109
12.

Increased protein damage in renal glomeruli, retina, nerve, plasma and urine and its prevention by thiamine and benfotiamine therapy in a rat model of diabetes.

Karachalias N, Babaei-Jadidi R, Rabbani N, Thornalley PJ.

Diabetologia. 2010 Jul;53(7):1506-16. doi: 10.1007/s00125-010-1722-z. Epub 2010 Apr 6.

PMID:
20369223
13.

Vitamin B1 blocks damage caused by hyperglycemia.

Obrenovich ME, Monnier VM.

Sci Aging Knowledge Environ. 2003 Mar 12;2003(10):PE6.

PMID:
12844520
14.

Benfotiamine accelerates the healing of ischaemic diabetic limbs in mice through protein kinase B/Akt-mediated potentiation of angiogenesis and inhibition of apoptosis.

Gadau S, Emanueli C, Van Linthout S, Graiani G, Todaro M, Meloni M, Campesi I, Invernici G, Spillmann F, Ward K, Madeddu P.

Diabetologia. 2006 Feb;49(2):405-20. Epub 2006 Jan 17.

PMID:
16416271
15.

Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose.

Pomero F, Molinar Min A, La Selva M, Allione A, Molinatti GM, Porta M.

Acta Diabetol. 2001;38(3):135-8.

PMID:
11827434
16.

Current therapeutic interventions in the glycation pathway: evidence from clinical studies.

Engelen L, Stehouwer CD, Schalkwijk CG.

Diabetes Obes Metab. 2013 Aug;15(8):677-89. doi: 10.1111/dom.12058. Epub 2013 Jan 25. Review.

PMID:
23279611
17.

Ameliorative effect of combination of benfotiamine and fenofibrate in diabetes-induced vascular endothelial dysfunction and nephropathy in the rat.

Balakumar P, Chakkarwar VA, Singh M.

Mol Cell Biochem. 2009 Jan;320(1-2):149-62. doi: 10.1007/s11010-008-9917-z. Epub 2008 Oct 2.

PMID:
18830571
18.

Detection of transketolase in bone marrow-derived insulin-producing cells: benfotiamine enhances insulin synthesis and glucose metabolism.

Oh SH, Witek RP, Bae SH, Darwiche H, Jung Y, Pi L, Brown A, Petersen BE.

Stem Cells Dev. 2009 Jan-Feb;18(1):37-46. doi: 10.1089/scd.2007.0255.

19.

Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy.

Alkhalaf A, Kleefstra N, Groenier KH, Bilo HJ, Gans RO, Heeringa P, Scheijen JL, Schalkwijk CG, Navis GJ, Bakker SJ.

PLoS One. 2012;7(7):e40427. doi: 10.1371/journal.pone.0040427. Epub 2012 Jul 6.

20.

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