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Items: 1 to 20 of 117

1.

Non-animal sensitization testing: state-of-the-art.

Vandebriel RJ, van Loveren H.

Crit Rev Toxicol. 2010 May;40(5):389-404. doi: 10.3109/10408440903524262. Review.

PMID:
20180632
2.

Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH).

Lilienblum W, Dekant W, Foth H, Gebel T, Hengstler JG, Kahl R, Kramer PJ, Schweinfurth H, Wollin KM.

Arch Toxicol. 2008 Apr;82(4):211-36. doi: 10.1007/s00204-008-0279-9. Epub 2008 Mar 6.

PMID:
18322675
3.
4.

An integrated decision-tree testing strategy for eye irritation with respect to the requirements of the EU REACH legislation.

Grindon C, Combes R, Cronin MT, Roberts DW, Garrod JF.

Altern Lab Anim. 2008 Feb;36(1):81-92.

PMID:
18333716
5.

An integrated decision-tree testing strategy for skin sensitisation with respect to the requirements of the EU REACH legislation.

Grindon C, Combes R, Cronin MT, Roberts DW, Garrod JF.

Altern Lab Anim. 2008 Oct;36 Suppl 1:75-89.

PMID:
19025333
6.

Animal testing and alternative approaches for the human health risk assessment under the proposed new European chemicals regulation.

Höfer T, Gerner I, Gundert-Remy U, Liebsch M, Schulte A, Spielmann H, Vogel R, Wettig K.

Arch Toxicol. 2004 Oct;78(10):549-64. Epub 2004 May 29. Review.

PMID:
15170526
8.

A cell-based in vitro alternative to identify skin sensitizers by gene expression.

Hooyberghs J, Schoeters E, Lambrechts N, Nelissen I, Witters H, Schoeters G, Van Den Heuvel R.

Toxicol Appl Pharmacol. 2008 Aug 15;231(1):103-11. doi: 10.1016/j.taap.2008.03.014. Epub 2008 Apr 4.

PMID:
18466943
9.
10.

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials.

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. doi: 10.1016/j.fct.2008.02.008. Epub 2008 Feb 13. Review.

PMID:
18328408
11.

Progress on the development of human in vitro dendritic cell based assays for assessment of the sensitizing potential of a compound.

dos Santos GG, Reinders J, Ouwehand K, Rustemeyer T, Scheper RJ, Gibbs S.

Toxicol Appl Pharmacol. 2009 May 1;236(3):372-82. doi: 10.1016/j.taap.2009.02.004. Epub 2009 Feb 14. Review.

PMID:
19232364
12.

Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro.

Emter R, Ellis G, Natsch A.

Toxicol Appl Pharmacol. 2010 Jun 15;245(3):281-90. doi: 10.1016/j.taap.2010.03.009. Epub 2010 Mar 20.

PMID:
20307559
13.

Reactivity profiling: covalent modification of single nucleophile peptides for skin sensitization risk assessment.

Aleksic M, Thain E, Roger D, Saib O, Davies M, Li J, Aptula A, Zazzeroni R.

Toxicol Sci. 2009 Apr;108(2):401-11. doi: 10.1093/toxsci/kfp030. Epub 2009 Feb 16.

PMID:
19221146
14.

Testing strategies in mutagenicity and genetic toxicology: an appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes.

Kirkland DJ, Henderson L, Marzin D, Müller L, Parry JM, Speit G, Tweats DJ, Williams GM.

Mutat Res. 2005 Dec 30;588(2):88-105. Epub 2005 Dec 2. Review.

PMID:
16326131
15.

Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals.

Bauch C, Kolle SN, Fabian E, Pachel C, Ramirez T, Wiench B, Wruck CJ, van Ravenzwaay B, Landsiedel R.

Toxicol In Vitro. 2011 Sep;25(6):1162-8. doi: 10.1016/j.tiv.2011.05.030. Epub 2011 Jun 7.

PMID:
21669280
16.
17.

Integrated decision-tree testing strategies for skin corrosion and irritation with respect to the requirements of the EU REACH legislation.

Grindon C, Combes R, Cronin MT, Roberts DW, Garrod JF.

Altern Lab Anim. 2008 Oct;36 Suppl 1:65-74.

PMID:
19025332
18.

An integrated decision-tree testing strategy for skin sensitisation with respect to the requirements of the EU REACH legislation.

Grindon C, Combes R, Cronin MT, Roberts DW, Garrod JF.

Altern Lab Anim. 2007 Dec;35(6):683-97.

PMID:
18186673
19.

Skin sensitisation: the Colipa strategy for developing and evaluating non-animal test methods for risk assessment.

Maxwell G, Aeby P, Ashikaga T, Bessou-Touya S, Diembeck W, Gerberick F, Kern P, Marrec-Fairley M, Ovigne JM, Sakaguchi H, Schroeder K, Tailhardat M, Teissier S, Winkler P.

ALTEX. 2011;28(1):50-5.

20.

Non-enzymatic glutathione reactivity and in vitro toxicity: a non-animal approach to skin sensitization.

Aptula AO, Patlewicz G, Roberts DW, Schultz TW.

Toxicol In Vitro. 2006 Mar;20(2):239-47. Epub 2005 Aug 19.

PMID:
16112535

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