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Carbon nanotubes elicit DNA damage and inflammatory response relative to their size and shape.

Yamashita K, Yoshioka Y, Higashisaka K, Morishita Y, Yoshida T, Fujimura M, Kayamuro H, Nabeshi H, Yamashita T, Nagano K, Abe Y, Kamada H, Kawai Y, Mayumi T, Yoshikawa T, Itoh N, Tsunoda S, Tsutsumi Y.

Inflammation. 2010 Aug;33(4):276-80. doi: 10.1007/s10753-010-9182-7.


Genotoxicity of short single-wall and multi-wall carbon nanotubes in human bronchial epithelial and mesothelial cells in vitro.

Lindberg HK, Falck GC, Singh R, Suhonen S, Järventaus H, Vanhala E, Catalán J, Farmer PB, Savolainen KM, Norppa H.

Toxicology. 2013 Nov 8;313(1):24-37. doi: 10.1016/j.tox.2012.12.008. Epub 2012 Dec 21.


Occupational nanosafety considerations for carbon nanotubes and carbon nanofibers.

Castranova V, Schulte PA, Zumwalde RD.

Acc Chem Res. 2013 Mar 19;46(3):642-9. doi: 10.1021/ar300004a. Epub 2012 Dec 5.


Pulmonary and pleural inflammation after intratracheal instillation of short single-walled and multi-walled carbon nanotubes.

Fujita K, Fukuda M, Endoh S, Maru J, Kato H, Nakamura A, Shinohara N, Uchino K, Honda K.

Toxicol Lett. 2016 Aug 22;257:23-37. doi: 10.1016/j.toxlet.2016.05.025. Epub 2016 May 31.


MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs.

Poulsen SS, Saber AT, Williams A, Andersen O, Købler C, Atluri R, Pozzebon ME, Mucelli SP, Simion M, Rickerby D, Mortensen A, Jackson P, Kyjovska ZO, Mølhave K, Jacobsen NR, Jensen KA, Yauk CL, Wallin H, Halappanavar S, Vogel U.

Toxicol Appl Pharmacol. 2015 Apr 1;284(1):16-32. doi: 10.1016/j.taap.2014.12.011. Epub 2014 Dec 29.


Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes.

Sargent LM, Porter DW, Staska LM, Hubbs AF, Lowry DT, Battelli L, Siegrist KJ, Kashon ML, Mercer RR, Bauer AK, Chen BT, Salisbury JL, Frazer D, McKinney W, Andrew M, Tsuruoka S, Endo M, Fluharty KL, Castranova V, Reynolds SH.

Part Fibre Toxicol. 2014 Jan 9;11:3. doi: 10.1186/1743-8977-11-3.


Carboxylated short single-walled carbon nanotubes but not plain and multi-walled short carbon nanotubes show in vitro genotoxicity.

Mrakovcic M, Meindl C, Leitinger G, Roblegg E, Fröhlich E.

Toxicol Sci. 2015 Mar;144(1):114-27. doi: 10.1093/toxsci/kfu260. Epub 2014 Dec 10.


The carcinogenic effect of various multi-walled carbon nanotubes (MWCNTs) after intraperitoneal injection in rats.

Rittinghausen S, Hackbarth A, Creutzenberg O, Ernst H, Heinrich U, Leonhardt A, Schaudien D.

Part Fibre Toxicol. 2014 Nov 20;11:59. doi: 10.1186/s12989-014-0059-z.


A review of carbon nanotube toxicity and assessment of potential occupational and environmental health risks.

Lam CW, James JT, McCluskey R, Arepalli S, Hunter RL.

Crit Rev Toxicol. 2006 Mar;36(3):189-217. Review.


Effects of single and multi walled carbon nanotubes on macrophages: cyto and genotoxicity and electron microscopy.

Di Giorgio ML, Di Bucchianico S, Ragnelli AM, Aimola P, Santucci S, Poma A.

Mutat Res. 2011 May 18;722(1):20-31. doi: 10.1016/j.mrgentox.2011.02.008. Epub 2011 Mar 4.


Mapping differential cellular protein response of mouse alveolar epithelial cells to multi-walled carbon nanotubes as a function of atomic layer deposition coating.

Hilton GM, Taylor AJ, Hussain S, Dandley EC, Griffith EH, Garantziotis S, Parsons GN, Bonner JC, Bereman MS.

Nanotoxicology. 2017 Apr;11(3):313-326. doi: 10.1080/17435390.2017.1299888. Epub 2017 Mar 13.


Single-walled and multi-walled carbon nanotubes promote allergic immune responses in mice.

Nygaard UC, Hansen JS, Samuelsen M, Alberg T, Marioara CD, Løvik M.

Toxicol Sci. 2009 May;109(1):113-23. doi: 10.1093/toxsci/kfp057. Epub 2009 Mar 17.


Apoptotic, inflammatory, and fibrogenic effects of two different types of multi-walled carbon nanotubes in mouse lung.

van Berlo D, Wilhelmi V, Boots AW, Hullmann M, Kuhlbusch TA, Bast A, Schins RP, Albrecht C.

Arch Toxicol. 2014 Sep;88(9):1725-37. doi: 10.1007/s00204-014-1220-z. Epub 2014 Mar 25.


Biological responses according to the shape and size of carbon nanotubes in BEAS-2B and MESO-1 cells.

Haniu H, Saito N, Matsuda Y, Tsukahara T, Usui Y, Maruyama K, Takanashi S, Aoki K, Kobayashi S, Nomura H, Tanaka M, Okamoto M, Kato H.

Int J Nanomedicine. 2014 Apr 17;9:1979-90. doi: 10.2147/IJN.S58661. eCollection 2014.


Size effects of single-walled carbon nanotubes on in vivo and in vitro pulmonary toxicity.

Fujita K, Fukuda M, Endoh S, Maru J, Kato H, Nakamura A, Shinohara N, Uchino K, Honda K.

Inhal Toxicol. 2015 Mar;27(4):207-23. doi: 10.3109/08958378.2015.1026620. Epub 2015 Apr 13.


Systemic and immunotoxicity of pristine and PEGylated multi-walled carbon nanotubes in an intravenous 28 days repeated dose toxicity study.

Zhang T, Tang M, Zhang S, Hu Y, Li H, Zhang T, Xue Y, Pu Y.

Int J Nanomedicine. 2017 Feb 27;12:1539-1554. doi: 10.2147/IJN.S123345. eCollection 2017.


Exposure and emission measurements during production, purification, and functionalization of arc-discharge-produced multi-walled carbon nanotubes.

Hedmer M, Isaxon C, Nilsson PT, Ludvigsson L, Messing ME, Genberg J, Skaug V, Bohgard M, Tinnerberg H, Pagels JH.

Ann Occup Hyg. 2014 Apr;58(3):355-79. doi: 10.1093/annhyg/met072. Epub 2014 Jan 3.


Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice.

Christophersen DV, Jacobsen NR, Andersen MH, Connell SP, Barfod KK, Thomsen MB, Miller MR, Duffin R, Lykkesfeldt J, Vogel U, Wallin H, Loft S, Roursgaard M, Møller P.

Toxicology. 2016 Sep 14;371:29-40. doi: 10.1016/j.tox.2016.10.003. Epub 2016 Oct 8.


Persistent DNA damage measured by comet assay of Sprague Dawley rat lung cells after five days of inhalation exposure and 1 month post-exposure to dispersed multi-wall carbon nanotubes (MWCNTs) generated by new MWCNT aerosol generation system.

Kim JS, Sung JH, Song KS, Lee JH, Kim SM, Lee GH, Ahn KH, Lee JS, Shin JH, Park JD, Yu IJ.

Toxicol Sci. 2012 Aug;128(2):439-48. doi: 10.1093/toxsci/kfs161. Epub 2012 Apr 26.


Time-dependent subcellular distribution and effects of carbon nanotubes in lungs of mice.

Købler C, Poulsen SS, Saber AT, Jacobsen NR, Wallin H, Yauk CL, Halappanavar S, Vogel U, Qvortrup K, Mølhave K.

PLoS One. 2015 Jan 23;10(1):e0116481. doi: 10.1371/journal.pone.0116481. eCollection 2015.

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