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S100A8 and S100A9 inhibit neutrophil oxidative metabolism in-vitro: involvement of adenosine metabolites.

Sroussi HY, Lu Y, Zhang QL, Villines D, Marucha PT.

Free Radic Res. 2010 Apr;44(4):389-96. doi: 10.3109/10715760903431434.


Effect of human immunodeficiency virus infection on S100A8/A9 inhibition of peripheral neutrophils oxidative metabolism.

Schwartz R, Lu Y, Villines D, Sroussi HY.

Biomed Pharmacother. 2010 Oct;64(8):572-5. doi: 10.1016/j.biopha.2010.03.005.


The down regulation of neutrophil oxidative metabolism by S100A8 and S100A9: implication of the protease-activated receptor-2.

Sroussi HY, Lu Y, Villines D, Sun Y.

Mol Immunol. 2012 Feb;50(1-2):42-8. doi: 10.1016/j.molimm.2011.12.001.


Substitution of methionine 63 or 83 in S100A9 and cysteine 42 in S100A8 abrogate the antifungal activities of S100A8/A9: potential role for oxidative regulation.

Sroussi HY, Köhler GA, Agabian N, Villines D, Palefsky JM.

FEMS Immunol Med Microbiol. 2009 Jan;55(1):55-61. doi: 10.1111/j.1574-695X.2008.00498.x.


Blockade of S100A8 and S100A9 suppresses neutrophil migration in response to lipopolysaccharide.

Vandal K, Rouleau P, Boivin A, Ryckman C, Talbot M, Tessier PA.

J Immunol. 2003 Sep 1;171(5):2602-9.


Proinflammatory activities of S100: proteins S100A8, S100A9, and S100A8/A9 induce neutrophil chemotaxis and adhesion.

Ryckman C, Vandal K, Rouleau P, Talbot M, Tessier PA.

J Immunol. 2003 Mar 15;170(6):3233-42.


Molecular interface of S100A8 with cytochrome b558 and NADPH oxidase activation.

Berthier S, Nguyen MV, Baillet A, Hograindleur MA, Paclet MH, Polack B, Morel F.

PLoS One. 2012;7(7):e40277. doi: 10.1371/journal.pone.0040277.


Secretion of S100A8, S100A9, and S100A12 by Neutrophils Involves Reactive Oxygen Species and Potassium Efflux.

Tardif MR, Chapeton-Montes JA, Posvandzic A, Pagé N, Gilbert C, Tessier PA.

J Immunol Res. 2015;2015:296149. doi: 10.1155/2015/296149.


Monosodium urate monohydrate crystals induce the release of the proinflammatory protein S100A8/A9 from neutrophils.

Ryckman C, Gilbert C, de Médicis R, Lussier A, Vandal K, Tessier PA.

J Leukoc Biol. 2004 Aug;76(2):433-40.


S100a8/a9 released by CD11b+Gr1+ neutrophils activates cardiac fibroblasts to initiate angiotensin II-Induced cardiac inflammation and injury.

Wu Y, Li Y, Zhang C, A X, Wang Y, Cui W, Li H, Du J.

Hypertension. 2014 Jun;63(6):1241-50. doi: 10.1161/HYPERTENSIONAHA.113.02843.


S100A8 and S100A9 in human arterial wall. Implications for atherogenesis.

McCormick MM, Rahimi F, Bobryshev YV, Gaus K, Zreiqat H, Cai H, Lord RS, Geczy CL.

J Biol Chem. 2005 Dec 16;280(50):41521-9.


Oxidation of methionine 63 and 83 regulates the effect of S100A9 on the migration of neutrophils in vitro.

Sroussi HY, Berline J, Palefsky JM.

J Leukoc Biol. 2007 Mar;81(3):818-24.


iPLA2, a novel determinant in Ca2+- and phosphorylation-dependent S100A8/A9 regulated NOX2 activity.

Schenten V, Bréchard S, Plançon S, Melchior C, Frippiat JP, Tschirhart EJ.

Biochim Biophys Acta. 2010 Jul;1803(7):840-7. doi: 10.1016/j.bbamcr.2010.02.006. Erratum in: Biochim Biophys Acta. 2011 Dec;1813(12):2196.


S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity.

Nacken W, Roth J, Sorg C, Kerkhoff C.

Microsc Res Tech. 2003 Apr 15;60(6):569-80. Review.


S-glutathionylation regulates inflammatory activities of S100A9.

Lim SY, Raftery MJ, Goyette J, Geczy CL.

J Biol Chem. 2010 May 7;285(19):14377-88. doi: 10.1074/jbc.M109.075242.


S100A8 and S100A9 in inflammation and cancer.

Gebhardt C, Németh J, Angel P, Hess J.

Biochem Pharmacol. 2006 Nov 30;72(11):1622-31. Review.


S100A8 and S100A9 activate MAP kinase and NF-kappaB signaling pathways and trigger translocation of RAGE in human prostate cancer cells.

Hermani A, De Servi B, Medunjanin S, Tessier PA, Mayer D.

Exp Cell Res. 2006 Jan 15;312(2):184-97.


Plasma S100A8/A9 correlates with blood neutrophil counts, traditional risk factors, and cardiovascular disease in middle-aged healthy individuals.

Cotoi OS, Dunér P, Ko N, Hedblad B, Nilsson J, Björkbacka H, Schiopu A.

Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):202-10. doi: 10.1161/ATVBAHA.113.302432.


Role of S100A8 and S100A9 in neutrophil recruitment in response to monosodium urate monohydrate crystals in the air-pouch model of acute gouty arthritis.

Ryckman C, McColl SR, Vandal K, de Médicis R, Lussier A, Poubelle PE, Tessier PA.

Arthritis Rheum. 2003 Aug;48(8):2310-20.


Oxidative modifications of DAMPs suppress inflammation: the case for S100A8 and S100A9.

Lim SY, Raftery MJ, Geczy CL.

Antioxid Redox Signal. 2011 Oct 15;15(8):2235-48. doi: 10.1089/ars.2010.3641. Review.

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