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Items: 1 to 20 of 91

1.

Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy.

Wu JJ, Quijano C, Chen E, Liu H, Cao L, Fergusson MM, Rovira II, Gutkind S, Daniels MP, Komatsu M, Finkel T.

Aging (Albany NY). 2009 Apr 9;1(4):425-37.

2.

Role of autophagy in diabetes and mitochondria.

Jung HS, Lee MS.

Ann N Y Acad Sci. 2010 Jul;1201:79-83. doi: 10.1111/j.1749-6632.2010.05614.x. Review.

PMID:
20649543
3.

Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia.

Jung HS, Chung KW, Won Kim J, Kim J, Komatsu M, Tanaka K, Nguyen YH, Kang TM, Yoon KH, Kim JW, Jeong YT, Han MS, Lee MK, Kim KW, Shin J, Lee MS.

Cell Metab. 2008 Oct;8(4):318-24. doi: 10.1016/j.cmet.2008.08.013.

4.

Autophagy is not required to sustain exercise and PRKAA1/AMPK activity but is important to prevent mitochondrial damage during physical activity.

Lo Verso F, Carnio S, Vainshtein A, Sandri M.

Autophagy. 2014;10(11):1883-94. doi: 10.4161/auto.32154. Epub 2014 Oct 30.

5.

Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors.

Strohecker AM, Guo JY, Karsli-Uzunbas G, Price SM, Chen GJ, Mathew R, McMahon M, White E.

Cancer Discov. 2013 Nov;3(11):1272-85. doi: 10.1158/2159-8290.CD-13-0397. Epub 2013 Aug 21.

6.

ATP13A2 regulates mitochondrial bioenergetics through macroautophagy.

Gusdon AM, Zhu J, Van Houten B, Chu CT.

Neurobiol Dis. 2012 Mar;45(3):962-72. doi: 10.1016/j.nbd.2011.12.015. Epub 2011 Dec 13.

7.

β-cell autophagy: A novel mechanism regulating β-cell function and mass: Lessons from β-cell-specific Atg7-deficient mice.

Fujitani Y, Ebato C, Uchida T, Kawamori R, Watada H.

Islets. 2009 Sep-Oct;1(2):151-3. doi: 10.4161/isl.1.2.9057.

PMID:
21099263
8.

A "radical" mitochondrial view of autophagy-related pathology.

Raimundo N, Shadel GS.

Aging (Albany NY). 2009 Apr 8;1(4):354-6. No abstract available.

9.
10.

Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita(+/Ins2)-derived β-cells.

Mitchell T, Johnson MS, Ouyang X, Chacko BK, Mitra K, Lei X, Gai Y, Moore DR, Barnes S, Zhang J, Koizumi A, Ramanadham S, Darley-Usmar VM.

Am J Physiol Endocrinol Metab. 2013 Sep 1;305(5):E585-99. doi: 10.1152/ajpendo.00093.2013. Epub 2013 Jul 2.

11.

VAMP7 Regulates Autophagy to Maintain Mitochondrial Homeostasis and to Control Insulin Secretion in Pancreatic β-Cells.

Aoyagi K, Ohara-Imaizumi M, Itakura M, Torii S, Akimoto Y, Nishiwaki C, Nakamichi Y, Kishimoto T, Kawakami H, Harada A, Takahashi M, Nagamatsu S.

Diabetes. 2016 Jun;65(6):1648-59. doi: 10.2337/db15-1207. Epub 2016 Mar 7.

12.

Increased expression of ERp57/GRP58 is protective against pancreatic beta cell death caused by autophagic failure.

Yamamoto E, Uchida T, Abe H, Taka H, Fujimura T, Komiya K, Hara A, Ogihara T, Fujitani Y, Ueno T, Takeda S, Watada H.

Biochem Biophys Res Commun. 2014 Oct 10;453(1):19-24. doi: 10.1016/j.bbrc.2014.09.040. Epub 2014 Sep 19.

PMID:
25241190
13.

Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis.

Zhang Y, Goldman S, Baerga R, Zhao Y, Komatsu M, Jin S.

Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19860-5. doi: 10.1073/pnas.0906048106. Epub 2009 Nov 12.

14.

Mitochondrial Complexes I and II Are More Susceptible to Autophagy Deficiency in Mouse β-Cells.

Kim MJ, Choi OK, Chae KS, Kim MK, Kim JH, Komatsu M, Tanaka K, Lee H, Chung SS, Kwak SH, Cho YM, Park KS, Jung HS.

Endocrinol Metab (Seoul). 2015 Mar 27;30(1):65-70. doi: 10.3803/EnM.2015.30.1.65. Epub 2014 Jul 2.

15.

Deficient Autophagy Results in Mitochondrial Dysfunction and FSGS.

Kawakami T, Gomez IG, Ren S, Hudkins K, Roach A, Alpers CE, Shankland SJ, D'Agati VD, Duffield JS.

J Am Soc Nephrol. 2015 May;26(5):1040-52. doi: 10.1681/ASN.2013111202. Epub 2014 Nov 18.

16.

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo.

Mortensen M, Ferguson DJ, Edelmann M, Kessler B, Morten KJ, Komatsu M, Simon AK.

Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):832-7. doi: 10.1073/pnas.0913170107. Epub 2009 Dec 22.

17.

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.

Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS.

EMBO J. 2008 Jan 23;27(2):433-46. doi: 10.1038/sj.emboj.7601963. Epub 2008 Jan 17.

18.

Autophagy: a sweet process in diabetes.

Meijer AJ, Codogno P.

Cell Metab. 2008 Oct;8(4):275-6. doi: 10.1016/j.cmet.2008.09.001.

19.

Exendin-4 improves β-cell function in autophagy-deficient β-cells.

Abe H, Uchida T, Hara A, Mizukami H, Komiya K, Koike M, Shigihara N, Toyofuku Y, Ogihara T, Uchiyama Y, Yagihashi S, Fujitani Y, Watada H.

Endocrinology. 2013 Dec;154(12):4512-24. doi: 10.1210/en.2013-1578. Epub 2013 Oct 8.

PMID:
24105478
20.

Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic β-cells.

Quan W, Lim YM, Lee MS.

Exp Mol Med. 2012 Feb 29;44(2):81-8. doi: 10.3858/emm.2012.44.2.030. Review.

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