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Items: 1 to 20 of 121

1.

High-resolution imaging of brain 5-HT 1B receptors in the rhesus monkey using [11C]P943.

Nabulsi N, Huang Y, Weinzimmer D, Ropchan J, Frost JJ, McCarthy T, Carson RE, Ding YS.

Nucl Med Biol. 2010 Feb;37(2):205-14. doi: 10.1016/j.nucmedbio.2009.10.007. Epub 2009 Dec 1.

2.

Assessing the sensitivity of [¹¹C]p943, a novel 5-HT1B radioligand, to endogenous serotonin release.

Cosgrove KP, Kloczynski T, Nabulsi N, Weinzimmer D, Lin SF, Staley JK, Bhagwagar Z, Carson RE.

Synapse. 2011 Oct;65(10):1113-7. doi: 10.1002/syn.20942. Epub 2011 May 3.

3.

Kinetic modeling of the serotonin 5-HT(1B) receptor radioligand [(11)C]P943 in humans.

Gallezot JD, Nabulsi N, Neumeister A, Planeta-Wilson B, Williams WA, Singhal T, Kim S, Maguire RP, McCarthy T, Frost JJ, Huang Y, Ding YS, Carson RE.

J Cereb Blood Flow Metab. 2010 Jan;30(1):196-210. doi: 10.1038/jcbfm.2009.195. Epub 2009 Sep 23.

4.

Characterization of in vivo pharmacological properties and sensitivity to endogenous serotonin of [11C] P943: a positron emission tomography study in Papio anubis.

Ridler K, Plisson C, Rabiner EA, Gunn RN, Easwaramoorthy B, Abi-Dargham A, Laruelle M, Slifstein M.

Synapse. 2011 Nov;65(11):1119-27. doi: 10.1002/syn.20946. Epub 2011 May 19.

PMID:
21538549
5.

Serotonin 1B receptor imaging in alcohol dependence.

Hu J, Henry S, Gallezot JD, Ropchan J, Neumaier JF, Potenza MN, Sinha R, Krystal JH, Huang Y, Ding YS, Carson RE, Neumeister A.

Biol Psychiatry. 2010 May 1;67(9):800-3. doi: 10.1016/j.biopsych.2009.12.028. Epub 2010 Feb 20.

6.

Reduced ventral striatal/ventral pallidal serotonin1B receptor binding potential in major depressive disorder.

Murrough JW, Henry S, Hu J, Gallezot JD, Planeta-Wilson B, Neumaier JF, Neumeister A.

Psychopharmacology (Berl). 2011 Feb;213(2-3):547-53. doi: 10.1007/s00213-010-1881-0. Epub 2010 May 18.

7.

Age effects on serotonin receptor 1B as assessed by PET.

Matuskey D, Pittman B, Planeta-Wilson B, Walderhaug E, Henry S, Gallezot JD, Nabulsi N, Ding YS, Bhagwagar Z, Malison R, Carson RE, Neumeister A.

J Nucl Med. 2012 Sep;53(9):1411-4. doi: 10.2967/jnumed.112.103598. Epub 2012 Jul 31.

8.

[11C]AZ10419369: a selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain.

Pierson ME, Andersson J, Nyberg S, McCarthy DJ, Finnema SJ, Varnäs K, Takano A, Karlsson P, Gulyás B, Medd AM, Lee CM, Powell ME, Heys JR, Potts W, Seneca N, Mrzljak L, Farde L, Halldin C.

Neuroimage. 2008 Jul 1;41(3):1075-85. doi: 10.1016/j.neuroimage.2008.02.063. Epub 2008 Mar 14.

PMID:
18434202
9.

The effect of early trauma exposure on serotonin type 1B receptor expression revealed by reduced selective radioligand binding.

Murrough JW, Czermak C, Henry S, Nabulsi N, Gallezot JD, Gueorguieva R, Planeta-Wilson B, Krystal JH, Neumaier JF, Huang Y, Ding YS, Carson RE, Neumeister A.

Arch Gen Psychiatry. 2011 Sep;68(9):892-900. doi: 10.1001/archgenpsychiatry.2011.91.

10.

[N-methyl-3H3]AZ10419369 binding to the 5-HT1B receptor: in vitro characterization and in vivo receptor occupancy.

Maier DL, Sobotka-Briner C, Ding M, Powell ME, Jiang Q, Hill G, Heys JR, Elmore CS, Pierson ME, Mrzljak L.

J Pharmacol Exp Ther. 2009 Jul;330(1):342-51. doi: 10.1124/jpet.109.150722. Epub 2009 Apr 28.

11.

Synthesis and initial evaluation of [11C](R)-RWAY in monkey-a new, simply labeled antagonist radioligand for imaging brain 5-HT1A receptors with PET.

McCarron JA, Zoghbi SS, Shetty HU, Vermeulen ES, Wikström HV, Ichise M, Yasuno F, Halldin C, Innis RB, Pike VW.

Eur J Nucl Med Mol Imaging. 2007 Oct;34(10):1670-82. Epub 2007 Jun 20.

PMID:
17579853
12.

Reductions in brain 5-HT1B receptor availability in primarily cocaine-dependent humans.

Matuskey D, Bhagwagar Z, Planeta B, Pittman B, Gallezot JD, Chen J, Wanyiri J, Najafzadeh S, Ropchan J, Geha P, Huang Y, Potenza MN, Neumeister A, Carson RE, Malison RT.

Biol Psychiatry. 2014 Nov 15;76(10):816-22. doi: 10.1016/j.biopsych.2013.11.022. Epub 2013 Nov 28.

13.

A PET Tracer for Brain α2C Adrenoceptors, (11)C-ORM-13070: Radiosynthesis and Preclinical Evaluation in Rats and Knockout Mice.

Arponen E, Helin S, Marjamäki P, Grönroos T, Holm P, Löyttyniemi E, Någren K, Scheinin M, Haaparanta-Solin M, Sallinen J, Solin O.

J Nucl Med. 2014 Jul;55(7):1171-7. doi: 10.2967/jnumed.113.135574. Epub 2014 May 5.

14.

Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain.

Nabulsi NB, Mercier J, Holden D, Carré S, Najafzadeh S, Vandergeten MC, Lin SF, Deo A, Price N, Wood M, Lara-Jaime T, Montel F, Laruelle M, Carson RE, Hannestad J, Huang Y.

J Nucl Med. 2016 May;57(5):777-84. doi: 10.2967/jnumed.115.168179. Epub 2016 Feb 4.

15.

Development of a PET radioligand for the central 5-HT1B receptor: radiosynthesis and characterization in cynomolgus monkeys of eight radiolabeled compounds.

Andersson JD, Pierson ME, Finnema SJ, Gulyás B, Heys R, Elmore CS, Farde L, Halldin C.

Nucl Med Biol. 2011 Feb;38(2):261-72. doi: 10.1016/j.nucmedbio.2010.08.006. Epub 2010 Dec 3.

PMID:
21315282
16.

Determination of in vivo Bmax and Kd for 11C-GR103545, an agonist PET tracer for κ-opioid receptors: a study in nonhuman primates.

Tomasi G, Nabulsi N, Zheng MQ, Weinzimmer D, Ropchan J, Blumberg L, Brown-Proctor C, Ding YS, Carson RE, Huang Y.

J Nucl Med. 2013 Apr;54(4):600-8. doi: 10.2967/jnumed.112.112672. Epub 2013 Feb 19.

17.

Test-retest reliability of the novel 5-HT1B receptor PET radioligand [11C]P943.

Saricicek A, Chen J, Planeta B, Ruf B, Subramanyam K, Maloney K, Matuskey D, Labaree D, Deserno L, Neumeister A, Krystal JH, Gallezot JD, Huang Y, Carson RE, Bhagwagar Z.

Eur J Nucl Med Mol Imaging. 2015 Mar;42(3):468-77. doi: 10.1007/s00259-014-2958-5. Epub 2014 Nov 27.

PMID:
25427881
18.

Synthesis and biologic evaluation of a novel serotonin 5-HT1A receptor radioligand, 18F-labeled mefway, in rodents and imaging by PET in a nonhuman primate.

Saigal N, Pichika R, Easwaramoorthy B, Collins D, Christian BT, Shi B, Narayanan TK, Potkin SG, Mukherjee J.

J Nucl Med. 2006 Oct;47(10):1697-706.

19.

Quantitative analysis of [11C]AZ10419369 binding to 5-HT1B receptors in human brain.

Varnäs K, Nyberg S, Halldin C, Varrone A, Takano A, Karlsson P, Andersson J, McCarthy D, Smith M, Pierson ME, Söderström J, Farde L.

J Cereb Blood Flow Metab. 2011 Jan;31(1):113-23. doi: 10.1038/jcbfm.2010.55. Epub 2010 Apr 28.

20.

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