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Items: 1 to 20 of 90

1.

Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity.

Takata K, Arana ME, Seki M, Kunkel TA, Wood RD.

Nucleic Acids Res. 2010 Jun;38(10):3233-44. doi: 10.1093/nar/gkq048. Epub 2010 Feb 9.

2.

Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol.

Takata K, Shimizu T, Iwai S, Wood RD.

J Biol Chem. 2006 Aug 18;281(33):23445-55. Epub 2006 Jun 19. Erratum in: J Biol Chem. 2007 Apr 27;282(17):13139.

3.

Conserved overlapping gene arrangement, restricted expression, and biochemical activities of DNA polymerase ν (POLN).

Takata K, Tomida J, Reh S, Swanhart LM, Takata M, Hukriede NA, Wood RD.

J Biol Chem. 2015 Oct 2;290(40):24278-93. doi: 10.1074/jbc.M115.677419. Epub 2015 Aug 12.

4.

High-efficiency bypass of DNA damage by human DNA polymerase Q.

Seki M, Masutani C, Yang LW, Schuffert A, Iwai S, Bahar I, Wood RD.

EMBO J. 2004 Nov 10;23(22):4484-94. Epub 2004 Oct 21.

5.

Mutation of the little finger domain in human DNA polymerase η alters fidelity when copying undamaged DNA.

Beardslee RA, Suarez SC, Toffton SM, McCulloch SD.

Environ Mol Mutagen. 2013 Oct;54(8):638-51. doi: 10.1002/em.21807. Epub 2013 Aug 1.

6.

Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts.

Hogg M, Seki M, Wood RD, Doublié S, Wallace SS.

J Mol Biol. 2011 Jan 21;405(3):642-52. doi: 10.1016/j.jmb.2010.10.041. Epub 2010 Nov 2. Erratum in: J Mol Biol. 2011 Sep 16;412(2):316.

7.

Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta.

Glick E, Chau JS, Vigna KL, McCulloch SD, Adman ET, Kunkel TA, Loeb LA.

J Biol Chem. 2003 May 23;278(21):19341-6. Epub 2003 Mar 18.

8.
9.

A unique error signature for human DNA polymerase nu.

Arana ME, Takata K, Garcia-Diaz M, Wood RD, Kunkel TA.

DNA Repair (Amst). 2007 Feb 4;6(2):213-23. Epub 2006 Nov 21.

10.

Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7.

Rodriguez AC, Park HW, Mao C, Beese LS.

J Mol Biol. 2000 Jun 2;299(2):447-62.

PMID:
10860752
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14.

NMR mapping of PCNA interaction with translesion synthesis DNA polymerase Rev1 mediated by Rev1-BRCT domain.

Pustovalova Y, Maciejewski MW, Korzhnev DM.

J Mol Biol. 2013 Sep 9;425(17):3091-105. doi: 10.1016/j.jmb.2013.05.029. Epub 2013 Jun 7.

PMID:
23747975
15.

ø29 DNA polymerase residue Lys383, invariant at motif B of DNA-dependent polymerases, is involved in dNTP binding.

Saturno J, Lázaro JM, Esteban FJ, Blanco L, Salas M.

J Mol Biol. 1997 Jun 13;269(3):313-25.

PMID:
9199402
16.

phi 29 DNA polymerase residue Leu384, highly conserved in motif B of eukaryotic type DNA replicases, is involved in nucleotide insertion fidelity.

Truniger V, Lázaro JM, de Vega M, Blanco L, Salas M.

J Biol Chem. 2003 Aug 29;278(35):33482-91. Epub 2003 Jun 12.

17.

Biochemical evolution of DNA polymerase eta: properties of plant, human, and yeast proteins.

Hoffman PD, Curtis MJ, Iwai S, Hays JB.

Biochemistry. 2008 Apr 22;47(16):4583-96. doi: 10.1021/bi701781p. Epub 2008 Mar 27.

PMID:
18366182
18.

Roles of the active site residues and metal cofactors in noncanonical base-pairing during catalysis by human DNA polymerase iota.

Makarova AV, Ignatov A, Miropolskaya N, Kulbachinskiy A.

DNA Repair (Amst). 2014 Oct;22:67-76. doi: 10.1016/j.dnarep.2014.07.006. Epub 2014 Aug 9.

PMID:
25108837
19.

The efficiency and specificity of apurinic/apyrimidinic site bypass by human DNA polymerase eta and Sulfolobus solfataricus Dpo4.

Kokoska RJ, McCulloch SD, Kunkel TA.

J Biol Chem. 2003 Dec 12;278(50):50537-45. Epub 2003 Sep 30.

20.

Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function.

Prakash S, Johnson RE, Prakash L.

Annu Rev Biochem. 2005;74:317-53. Review.

PMID:
15952890

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