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Items: 1 to 20 of 106

1.

Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance.

Zorzet A, Pavlov MY, Nilsson AI, Ehrenberg M, Andersson DI.

Mol Microbiol. 2010 Mar;75(5):1299-313. doi: 10.1111/j.1365-2958.2010.07057.x. Epub 2010 Feb 3.

2.

Activation of initiation factor 2 by ligands and mutations for rapid docking of ribosomal subunits.

Pavlov MY, Zorzet A, Andersson DI, Ehrenberg M.

EMBO J. 2011 Jan 19;30(2):289-301. doi: 10.1038/emboj.2010.328. Epub 2010 Dec 10.

3.

Reducing the fitness cost of antibiotic resistance by amplification of initiator tRNA genes.

Nilsson AI, Zorzet A, Kanth A, Dahlström S, Berg OG, Andersson DI.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):6976-81. Epub 2006 Apr 24.

5.

The Pseudomonas aeruginosa initiation factor IF-2 is responsible for formylation-independent protein initiation in P. aeruginosa.

Steiner-Mosonyi M, Creuzenet C, Keates RA, Strub BR, Mangroo D.

J Biol Chem. 2004 Dec 10;279(50):52262-9. Epub 2004 Sep 22.

6.

Requirements for translation re-initiation in Escherichia coli: roles of initiator tRNA and initiation factors IF2 and IF3.

Yoo JH, RajBhandary UL.

Mol Microbiol. 2008 Mar;67(5):1012-26. doi: 10.1111/j.1365-2958.2008.06104.x. Epub 2008 Jan 21.

8.

Inhibition of bacterial IF2 binding to fMet-tRNA((fMet)) by aminoglycosides.

Evans JM, Turner BA, Bowen S, Ho AM, Sarver RW, Benson E, Parker CN.

Bioorg Med Chem Lett. 2003 Mar 24;13(6):993-6.

PMID:
12643896
9.

The ribosome-bound initiation factor 2 recruits initiator tRNA to the 30S initiation complex.

Milon P, Carotti M, Konevega AL, Wintermeyer W, Rodnina MV, Gualerzi CO.

EMBO Rep. 2010 Apr;11(4):312-6. doi: 10.1038/embor.2010.12. Epub 2010 Mar 12.

10.

Characterization of mutations in the GTP-binding domain of IF2 resulting in cold-sensitive growth of Escherichia coli.

Laursen BS, Siwanowicz I, Larigauderie G, Hedegaard J, Ito K, Nakamura Y, Kenney JM, Mortensen KK, Sperling-Petersen HU.

J Mol Biol. 2003 Feb 14;326(2):543-51.

PMID:
12559921
11.

Initiation of protein synthesis in Saccharomyces cerevisiae mitochondria without formylation of the initiator tRNA.

Li Y, Holmes WB, Appling DR, RajBhandary UL.

J Bacteriol. 2000 May;182(10):2886-92.

12.

Thermodynamic characterization of ppGpp binding to EF-G or IF2 and of initiator tRNA binding to free IF2 in the presence of GDP, GTP, or ppGpp.

Mitkevich VA, Ermakov A, Kulikova AA, Tankov S, Shyp V, Soosaar A, Tenson T, Makarov AA, Ehrenberg M, Hauryliuk V.

J Mol Biol. 2010 Oct 8;402(5):838-46. doi: 10.1016/j.jmb.2010.08.016. Epub 2010 Aug 14.

PMID:
20713063
13.

Structural dynamics of bacterial translation initiation factor IF2.

Wienk H, Tishchenko E, Belardinelli R, Tomaselli S, Dongre R, Spurio R, Folkers GE, Gualerzi CO, Boelens R.

J Biol Chem. 2012 Mar 30;287(14):10922-32. doi: 10.1074/jbc.M111.333393. Epub 2012 Feb 3.

14.

The translation initiation functions of IF2: targets for thiostrepton inhibition.

Brandi L, Marzi S, Fabbretti A, Fleischer C, Hill WE, Gualerzi CO, Stephen Lodmell J.

J Mol Biol. 2004 Jan 23;335(4):881-94.

PMID:
14698286
15.

Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor.

Simonetti A, Marzi S, Billas IM, Tsai A, Fabbretti A, Myasnikov AG, Roblin P, Vaiana AC, Hazemann I, Eiler D, Steitz TA, Puglisi JD, Gualerzi CO, Klaholz BP.

Proc Natl Acad Sci U S A. 2013 Sep 24;110(39):15656-61. doi: 10.1073/pnas.1309578110. Epub 2013 Sep 12.

16.

Mitochondrial initiation factor 2 of Trypanosoma brucei binds imported formylated elongator-type tRNA(Met).

Charrière F, Tan TH, Schneider A.

J Biol Chem. 2005 Apr 22;280(16):15659-65. Epub 2005 Feb 23.

17.

Mammalian mitochondrial initiation factor 2 supports yeast mitochondrial translation without formylated initiator tRNA.

Tibbetts AS, Oesterlin L, Chan SY, Kramer G, Hardesty B, Appling DR.

J Biol Chem. 2003 Aug 22;278(34):31774-80. Epub 2003 Jun 10.

18.
19.

Mapping the fMet-tRNA(f)(Met) binding site of initiation factor IF2.

Guenneugues M, Caserta E, Brandi L, Spurio R, Meunier S, Pon CL, Boelens R, Gualerzi CO.

EMBO J. 2000 Oct 2;19(19):5233-40.

20.

Structure of the 30S translation initiation complex.

Simonetti A, Marzi S, Myasnikov AG, Fabbretti A, Yusupov M, Gualerzi CO, Klaholz BP.

Nature. 2008 Sep 18;455(7211):416-20. doi: 10.1038/nature07192. Epub 2008 Aug 31.

PMID:
18758445

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