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Items: 1 to 20 of 118

1.

The effects of EPA, DHA, and aspirin ingestion on plasma lysophospholipids and autotaxin.

Block RC, Duff R, Lawrence P, Kakinami L, Brenna JT, Shearer GC, Meednu N, Mousa S, Friedman A, Harris WS, Larson M, Georas S.

Prostaglandins Leukot Essent Fatty Acids. 2010 Feb-Mar;82(2-3):87-95. doi: 10.1016/j.plefa.2009.12.005. Epub 2010 Jan 27.

2.

The combination of EPA+DHA and low-dose aspirin ingestion reduces platelet function acutely whereas each alone may not in healthy humans.

Block RC, Kakinami L, Jonovich M, Antonetti I, Lawrence P, Meednu N, CalderonArtero P, Mousa SA, Brenna JT, Georas S.

Prostaglandins Leukot Essent Fatty Acids. 2012 Oct-Nov;87(4-5):143-51. doi: 10.1016/j.plefa.2012.08.007. Epub 2012 Sep 25.

3.

[Clinical introduction of lysophosphatidic acid and autotaxin assays].

Yatomi Y.

Rinsho Byori. 2010 Jun;58(6):631-5. Review. Japanese.

PMID:
20662276
4.

Suppression of lysophosphatidic acid and lysophosphatidylcholine formation in the plasma in vitro: proposal of a plasma sample preparation method for laboratory testing of these lipids.

Nakamura K, Kishimoto T, Ohkawa R, Okubo S, Tozuka M, Yokota H, Ikeda H, Ohshima N, Mizuno K, Yatomi Y.

Anal Biochem. 2007 Aug 1;367(1):20-7. Epub 2007 May 6.

PMID:
17568554
5.

A novel autotaxin inhibitor reduces lysophosphatidic acid levels in plasma and the site of inflammation.

Gierse J, Thorarensen A, Beltey K, Bradshaw-Pierce E, Cortes-Burgos L, Hall T, Johnston A, Murphy M, Nemirovskiy O, Ogawa S, Pegg L, Pelc M, Prinsen M, Schnute M, Wendling J, Wene S, Weinberg R, Wittwer A, Zweifel B, Masferrer J.

J Pharmacol Exp Ther. 2010 Jul;334(1):310-7. doi: 10.1124/jpet.110.165845. Epub 2010 Apr 14.

6.

Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis.

Pamuklar Z, Federico L, Liu S, Umezu-Goto M, Dong A, Panchatcharam M, Fulkerson Z, Berdyshev E, Natarajan V, Fang X, van Meeteren LA, Moolenaar WH, Mills GB, Morris AJ, Smyth SS.

J Biol Chem. 2009 Mar 13;284(11):7385-94. doi: 10.1074/jbc.M807820200. Epub 2009 Jan 12. Erratum in: J Biol Chem. 2009 Jul 31;284(31):21100. Fulerson, Zachary [corrected to Fulkerson, Zachary].

7.

The effects of aspirin on platelet function and lysophosphatidic acids depend on plasma concentrations of EPA and DHA.

Block RC, Abdolahi A, Tu X, Georas SN, Brenna JT, Phipps RP, Lawrence P, Mousa SA.

Prostaglandins Leukot Essent Fatty Acids. 2015 May;96:17-24. doi: 10.1016/j.plefa.2014.12.005. Epub 2014 Dec 22.

8.

Both plasma lysophosphatidic acid and serum autotaxin levels are increased in chronic hepatitis C.

Watanabe N, Ikeda H, Nakamura K, Ohkawa R, Kume Y, Aoki J, Hama K, Okudaira S, Tanaka M, Tomiya T, Yanase M, Tejima K, Nishikawa T, Arai M, Arai H, Omata M, Fujiwara K, Yatomi Y.

J Clin Gastroenterol. 2007 Jul;41(6):616-23.

PMID:
17577119
9.

The effects of aspirin and fish oil consumption on lysophosphatidylcholines and lysophosphatidic acids and their correlates with platelet aggregation in adults with diabetes mellitus.

Abdolahi A, Georas SN, Brenna JT, Cai X, Thevenet-Morrison K, Phipps RP, Lawrence P, Mousa SA, Block RC.

Prostaglandins Leukot Essent Fatty Acids. 2014 Feb-Mar;90(2-3):61-8. doi: 10.1016/j.plefa.2013.12.004. Epub 2013 Dec 18.

10.
11.

Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid.

Inoue M, Xie W, Matsushita Y, Chun J, Aoki J, Ueda H.

Neuroscience. 2008 Mar 18;152(2):296-8. doi: 10.1016/j.neuroscience.2007.12.041. Epub 2008 Jan 9.

PMID:
18280050
12.

Measurement of lysophospholipase D/autotaxin activity in human serum samples.

Nakamura K, Ohkawa R, Okubo S, Tozuka M, Okada M, Aoki S, Aoki J, Arai H, Ikeda H, Yatomi Y.

Clin Biochem. 2007 Feb;40(3-4):274-7. Epub 2006 Oct 19.

PMID:
17222397
13.

Mediators of pruritus during cholestasis.

Oude Elferink RP, Kremer AE, Beuers U.

Curr Opin Gastroenterol. 2011 May;27(3):289-93. doi: 10.1097/MOG.0b013e32834575e8. Review.

PMID:
21451412
14.

Lysophosphatidic acid is a potential mediator of cholestatic pruritus.

Kremer AE, Martens JJ, Kulik W, Ruëff F, Kuiper EM, van Buuren HR, van Erpecum KJ, Kondrackiene J, Prieto J, Rust C, Geenes VL, Williamson C, Moolenaar WH, Beuers U, Oude Elferink RP.

Gastroenterology. 2010 Sep;139(3):1008-18, 1018.e1. doi: 10.1053/j.gastro.2010.05.009. Epub 2010 Jun 19.

PMID:
20546739
15.

Synthesis and biological evaluation of phosphonate derivatives as autotaxin (ATX) inhibitors.

Cui P, Tomsig JL, McCalmont WF, Lee S, Becker CJ, Lynch KR, Macdonald TL.

Bioorg Med Chem Lett. 2007 Mar 15;17(6):1634-40. Epub 2007 Jan 13.

16.

Kinetic analysis of autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution.

Saunders LP, Cao W, Chang WC, Albright RA, Braddock DT, De La Cruz EM.

J Biol Chem. 2011 Aug 26;286(34):30130-41. doi: 10.1074/jbc.M111.246884. Epub 2011 Jun 30.

17.

Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid.

Kishi Y, Okudaira S, Tanaka M, Hama K, Shida D, Kitayama J, Yamori T, Aoki J, Fujimaki T, Arai H.

J Biol Chem. 2006 Jun 23;281(25):17492-500. Epub 2006 Apr 19.

18.

Lysophosphatidylmethanol is a pan lysophosphatidic acid receptor agonist and is produced by autotaxin in blood.

Endo T, Kano K, Motoki R, Hama K, Okudaira S, Ishida M, Ogiso H, Tanaka M, Matsuki N, Taguchi R, Kanai M, Shibasaki M, Arai H, Aoki J.

J Biochem. 2009 Aug;146(2):283-93. doi: 10.1093/jb/mvp068. Epub 2009 May 4.

PMID:
19416959
19.

Autotaxin structure-activity relationships revealed through lysophosphatidylcholine analogs.

North EJ, Osborne DA, Bridson PK, Baker DL, Parrill AL.

Bioorg Med Chem. 2009 May 1;17(9):3433-42. doi: 10.1016/j.bmc.2009.03.030. Epub 2009 Mar 21.

20.

Evaluation of inhibitory actions of flavonols and related substances on lysophospholipase d activity of serum autotaxin by a convenient assay using a chromogenic substrate.

Ueda K, Yoshihara M, Nakao M, Tanaka T, Sano S, Fukuzawa K, Tokumura A.

J Agric Food Chem. 2010 May 26;58(10):6053-63. doi: 10.1021/jf904155a.

PMID:
20415488

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