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Items: 1 to 20 of 100

1.

Functional exploration of the adult ovarian granulosa cell tumor-associated somatic FOXL2 mutation p.Cys134Trp (c.402C>G).

Benayoun BA, Caburet S, Dipietromaria A, Georges A, D'Haene B, Pandaranayaka PJ, L'Hôte D, Todeschini AL, Krishnaswamy S, Fellous M, De Baere E, Veitia RA.

PLoS One. 2010 Jan 20;5(1):e8789. doi: 10.1371/journal.pone.0008789.

2.

Adult ovarian granulosa cell tumor transcriptomics: prevalence of FOXL2 target genes misregulation gives insights into the pathogenic mechanism of the p.Cys134Trp somatic mutation.

Benayoun BA, Anttonen M, L'Hôte D, Bailly-Bechet M, Andersson N, Heikinheimo M, Veitia RA.

Oncogene. 2013 May 30;32(22):2739-46. doi: 10.1038/onc.2012.298.

PMID:
22797072
3.

The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors.

Schrader KA, Gorbatcheva B, Senz J, Heravi-Moussavi A, Melnyk N, Salamanca C, Maines-Bandiera S, Cooke SL, Leung P, Brenton JD, Gilks CB, Monahan J, Huntsman DG.

PLoS One. 2009 Nov 24;4(11):e7988. doi: 10.1371/journal.pone.0007988.

4.

The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary.

Jamieson S, Butzow R, Andersson N, Alexiadis M, Unkila-Kallio L, Heikinheimo M, Fuller PJ, Anttonen M.

Mod Pathol. 2010 Nov;23(11):1477-85. doi: 10.1038/modpathol.2010.145.

5.

Differential apoptotic activities of wild-type FOXL2 and the adult-type granulosa cell tumor-associated mutant FOXL2 (C134W).

Kim JH, Yoon S, Park M, Park HO, Ko JJ, Lee K, Bae J.

Oncogene. 2011 Apr 7;30(14):1653-63. doi: 10.1038/onc.2010.541.

PMID:
21119601
6.

The FOXL2 mutation (c.402C>G) in adult-type ovarian granulosa cell tumors of three Japanese patients: clinical report and review of the literature.

Takahashi A, Kimura F, Yamanaka A, Takebayashi A, Kita N, Takahashi K, Murakami T.

Tohoku J Exp Med. 2013;231(4):243-50. Review.

7.

The transcriptional targets of mutant FOXL2 in granulosa cell tumours.

Rosario R, Araki H, Print CG, Shelling AN.

PLoS One. 2012;7(9):e46270. doi: 10.1371/journal.pone.0046270.

8.

Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter.

Fleming NI, Knower KC, Lazarus KA, Fuller PJ, Simpson ER, Clyne CD.

PLoS One. 2010 Dec 20;5(12):e14389. doi: 10.1371/journal.pone.0014389.

9.

Absence of a FOXL2 mutation (402C→G) in the blood of adult-type granulosa cell tumor patients possessing the FOXL2 mutation.

Lee S, Kim TH, Won M, Ko JJ, Rho J, Lee K, Bae J.

Int J Gynecol Cancer. 2010 Nov;20(8):1341-3. doi: 10.1111/IGC.0b013e3181ff3e73.

PMID:
21051974
10.

Mutation of FOXL2 in granulosa-cell tumors of the ovary.

Shah SP, Köbel M, Senz J, Morin RD, Clarke BA, Wiegand KC, Leung G, Zayed A, Mehl E, Kalloger SE, Sun M, Giuliany R, Yorida E, Jones S, Varhol R, Swenerton KD, Miller D, Clement PB, Crane C, Madore J, Provencher D, Leung P, DeFazio A, Khattra J, Turashvili G, Zhao Y, Zeng T, Glover JN, Vanderhyden B, Zhao C, Parkinson CA, Jimenez-Linan M, Bowtell DD, Mes-Masson AM, Brenton JD, Aparicio SA, Boyd N, Hirst M, Gilks CB, Marra M, Huntsman DG.

N Engl J Med. 2009 Jun 25;360(26):2719-29. doi: 10.1056/NEJMoa0902542.

11.

Mutational analysis (c.402C>G) of the FOXL2 gene and immunohistochemical expression of the FOXL2 protein in testicular adult type granulosa cell tumors and incompletely differentiated sex cord stromal tumors.

Hes O, Vaněček T, Petersson F, Grossmann P, Hora M, Perez Montiel DM, Steiner P, Dvořák M, Michal M.

Appl Immunohistochem Mol Morphol. 2011 Jul;19(4):347-51. doi: 10.1097/PAI.0b013e3182039ef2.

PMID:
21293260
12.

Ovarian cellular fibromas lack FOXL2 mutations: a useful diagnostic adjunct in the distinction from diffuse adult granulosa cell tumor.

McCluggage WG, Singh N, Kommoss S, Huntsman DG, Gilks CB.

Am J Surg Pathol. 2013 Sep;37(9):1450-5. doi: 10.1097/PAS.0b013e31828e4f55.

PMID:
23774170
13.

FOXL2 molecular testing in ovarian neoplasms: diagnostic approach and procedural guidelines.

Kommoss S, Anglesio MS, Mackenzie R, Yang W, Senz J, Ho J, Bell L, Lee S, Lorette J, Huntsman DG, Blake Gilks C.

Mod Pathol. 2013 Jun;26(6):860-7. doi: 10.1038/modpathol.2012.226.

14.
15.

A current perspective on the pathological assessment of FOXL2 in adult-type granulosa cell tumours of the ovary.

Kommoss S, Gilks CB, Penzel R, Herpel E, Mackenzie R, Huntsman D, Schirmacher P, Anglesio M, Schmidt D, Kommoss F.

Histopathology. 2014 Feb;64(3):380-8. doi: 10.1111/his.12253.

PMID:
24192202
16.

Molecular pathogenesis in granulosa cell tumor is not only due to somatic FOXL2 mutation.

Wang WC, Lai YC.

J Ovarian Res. 2014 Sep 6;7:88. doi: 10.1186/s13048-014-0088-0.

17.

FOXL2 mutations in granulosa cell tumors occurring in males.

Lima JF, Jin L, de Araujo AR, Erikson-Johnson MR, Oliveira AM, Sebo TJ, Keeney GL, Medeiros F.

Arch Pathol Lab Med. 2012 Jul;136(7):825-8. doi: 10.5858/arpa.2011-0355-OA.

PMID:
22742556
18.

Prognostic significance of FOXL2 mutation and mRNA expression in adult and juvenile granulosa cell tumors of the ovary.

D'Angelo E, Mozos A, Nakayama D, Espinosa I, Catasus L, Muñoz J, Prat J.

Mod Pathol. 2011 Oct;24(10):1360-7. doi: 10.1038/modpathol.2011.95.

19.

The role of FOXL2 in the pathogenesis of adult ovarian granulosa cell tumours.

Rosario R, Cohen PA, Shelling AN.

Gynecol Oncol. 2014 May;133(2):382-7. doi: 10.1016/j.ygyno.2013.12.012. Review.

PMID:
24342437
20.

FOXL2 mutation and large-scale genomic imbalances in adult granulosa cell tumors of the ovary.

Geiersbach KB, Jarboe EA, Jahromi MS, Baker CL, Paxton CN, Tripp SR, Schiffman JD.

Cancer Genet. 2011 Nov;204(11):596-602. doi: 10.1016/j.cancergen.2011.10.002.

PMID:
22200085
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