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Items: 1 to 20 of 62

1.

The primary microcephaly 3 (MCPH3) interacting protein, p35 and its catalytic subunit, Cdk5, are centrosomal proteins.

Rosales JL, Rattner JB, Lee KY.

Cell Cycle. 2010 Feb 1;9(3):618-20. No abstract available.

PMID:
20081373
2.

Suppression of mutant Huntingtin aggregate formation by Cdk5/p35 through the effect on microtubule stability.

Kaminosono S, Saito T, Oyama F, Ohshima T, Asada A, Nagai Y, Nukina N, Hisanaga S.

J Neurosci. 2008 Aug 27;28(35):8747-55. doi: 10.1523/JNEUROSCI.0973-08.2008.

3.

Involvement of cyclin dependent kinase 5 and its activator p35 in staurosporine-induced apoptosis of cortical neurons.

Zhang BF, Peng FF, Zhang W, Shen H, Wu SB, Wu DC.

Acta Pharmacol Sin. 2004 Sep;25(9):1105-11.

4.

Identification of a novel, membrane-associated neuronal kinase, cyclin-dependent kinase 5/p35-regulated kinase.

Kesavapany S, Lau KF, Ackerley S, Banner SJ, Shemilt SJ, Cooper JD, Leigh PN, Shaw CE, McLoughlin DM, Miller CC.

J Neurosci. 2003 Jun 15;23(12):4975-83.

5.

Myristoylation of p39 and p35 is a determinant of cytoplasmic or nuclear localization of active cyclin-dependent kinase 5 complexes.

Asada A, Yamamoto N, Gohda M, Saito T, Hayashi N, Hisanaga S.

J Neurochem. 2008 Aug;106(3):1325-36. doi: 10.1111/j.1471-4159.2008.05500.x. Epub 2008 May 26.

6.

Enhanced activation of Ca2+/calmodulin-dependent protein kinase II upon downregulation of cyclin-dependent kinase 5-p35.

Hosokawa T, Saito T, Asada A, Ohshima T, Itakura M, Takahashi M, Fukunaga K, Hisanaga S.

J Neurosci Res. 2006 Sep;84(4):747-54.

PMID:
16802322
7.

Regulation of membrane association and kinase activity of Cdk5-p35 by phosphorylation of p35.

Sato K, Zhu YS, Saito T, Yotsumoto K, Asada A, Hasegawa M, Hisanaga S.

J Neurosci Res. 2007 Nov 1;85(14):3071-8.

PMID:
17671990
8.

Identifying novel substrates for mouse Cdk5 kinase using the yeast Saccharomyces cerevisiae.

Horiuchi Y, Asada A, Hisanaga S, Toh-e A, Nishizawa M.

Genes Cells. 2006 Dec;11(12):1393-404.

9.

Quantitative measurement of in vivo phosphorylation states of Cdk5 activator p35 by Phos-tag SDS-PAGE.

Hosokawa T, Saito T, Asada A, Fukunaga K, Hisanaga S.

Mol Cell Proteomics. 2010 Jun;9(6):1133-43. doi: 10.1074/mcp.M900578-MCP200. Epub 2010 Jan 23.

10.

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5.

Tsai LH, Delalle I, Caviness VS Jr, Chae T, Harlow E.

Nature. 1994 Sep 29;371(6496):419-23.

PMID:
8090221
11.

Protein kinase Czeta regulates Cdk5/p25 signaling during myogenesis.

de Thonel A, Ferraris SE, Pallari HM, Imanishi SY, Kochin V, Hosokawa T, Hisanaga S, Sahlgren C, Eriksson JE.

Mol Biol Cell. 2010 Apr 15;21(8):1423-34. doi: 10.1091/mbc.E09-10-0847. Epub 2010 Mar 3.

12.

The Notch signaling inhibitor DAPT down-regulates cdk5 activity and modulates the distribution of neuronal cytoskeletal proteins.

Kanungo J, Zheng YL, Amin ND, Pant HC.

J Neurochem. 2008 Sep;106(5):2236-48. doi: 10.1111/j.1471-4159.2008.05551.x. Epub 2008 Jul 4.

13.

Cyclin dependent kinase 5 and its interacting proteins in cell death induced in vivo by cyclophosphamide in developing mouse embryos.

Zhu Y, Lin L, Kim S, Quaglino D, Lockshin RA, Zakeri Z.

Cell Death Differ. 2002 Apr;9(4):421-30.

14.

p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway.

Patrick GN, Zhou P, Kwon YT, Howley PM, Tsai LH.

J Biol Chem. 1998 Sep 11;273(37):24057-64.

15.

Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex.

Zhang J, Li H, Yabut O, Fitzpatrick H, D'Arcangelo G, Herrup K.

J Neurosci. 2010 Apr 14;30(15):5219-28. doi: 10.1523/JNEUROSCI.5628-09.2010.

16.

Tumor necrosis factor-alpha regulates cyclin-dependent kinase 5 activity during pain signaling through transcriptional activation of p35.

Utreras E, Futatsugi A, Rudrabhatla P, Keller J, Iadarola MJ, Pant HC, Kulkarni AB.

J Biol Chem. 2009 Jan 23;284(4):2275-84. doi: 10.1074/jbc.M805052200. Epub 2008 Dec 2.

17.

p35/Cyclin-dependent kinase 5 is required for protection against beta-amyloid-induced cell death but not tau phosphorylation by ceramide.

Seyb KI, Ansar S, Li G, Bean J, Michaelis ML, Dobrowsky RT.

J Mol Neurosci. 2007;31(1):23-35.

PMID:
17416967
18.

CDK5 is present in sea urchin and starfish eggs and embryos and can interact with p35, cyclin E and cyclin B3.

Lozano JC, Schatt P, Vergé V, Gobinet J, Villey V, Peaucellier G.

Mol Reprod Dev. 2010 May;77(5):449-61. doi: 10.1002/mrd.21165.

PMID:
20198710
19.
20.

The protein SET binds the neuronal Cdk5 activator p35nck5a and modulates Cdk5/p35nck5a activity.

Qu D, Li Q, Lim HY, Cheung NS, Li R, Wang JH, Qi RZ.

J Biol Chem. 2002 Mar 1;277(9):7324-32. Epub 2001 Dec 10.

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