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Items: 1 to 20 of 147

1.

Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension.

Rajkumar R, Konishi K, Richards TJ, Ishizawar DC, Wiechert AC, Kaminski N, Ahmad F.

Am J Physiol Heart Circ Physiol. 2010 Apr;298(4):H1235-48. doi: 10.1152/ajpheart.00254.2009. Epub 2010 Jan 15.

2.

Macrophage bone morphogenic protein receptor 2 depletion in idiopathic pulmonary fibrosis and Group III pulmonary hypertension.

Chen NY, D Collum S, Luo F, Weng T, Le TT, M Hernandez A, Philip K, Molina JG, Garcia-Morales LJ, Cao Y, Ko TC, Amione-Guerra J, Al-Jabbari O, Bunge RR, Youker K, Bruckner BA, Hamid R, Davies J, Sinha N, Karmouty-Quintana H.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L238-54. doi: 10.1152/ajplung.00142.2016. Epub 2016 Jun 17.

3.

Impaired bone morphogenetic protein receptor II signaling in a transforming growth factor-β-dependent mouse model of pulmonary hypertension and in systemic sclerosis.

Gilbane AJ, Derrett-Smith E, Trinder SL, Good RB, Pearce A, Denton CP, Holmes AM.

Am J Respir Crit Care Med. 2015 Mar 15;191(6):665-77. doi: 10.1164/rccm.201408-1464OC.

PMID:
25606692
4.

Pulmonary arteriole gene expression signature in idiopathic pulmonary fibrosis.

Patel NM, Kawut SM, Jelic S, Arcasoy SM, Lederer DJ, Borczuk AC.

Eur Respir J. 2013 Jun;41(6):1324-30. doi: 10.1183/09031936.00084112.

5.

Mutations in bone morphogenetic protein type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: implications for familial pulmonary arterial hypertension.

Yang J, Davies RJ, Southwood M, Long L, Yang X, Sobolewski A, Upton PD, Trembath RC, Morrell NW.

Circ Res. 2008 May 23;102(10):1212-21. doi: 10.1161/CIRCRESAHA.108.173567. Epub 2008 Apr 24.

6.

Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance.

Flynn C, Zheng S, Yan L, Hedges L, Womack B, Fessel J, Cogan J, Austin E, Loyd J, West J, Zhao Z, Hamid R.

Am J Respir Cell Mol Biol. 2012 Jul;47(1):20-7. doi: 10.1165/rcmb.2011-0251OC. Epub 2012 Feb 3.

7.

Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia.

Trembath RC, Thomson JR, Machado RD, Morgan NV, Atkinson C, Winship I, Simonneau G, Galie N, Loyd JE, Humbert M, Nichols WC, Morrell NW, Berg J, Manes A, McGaughran J, Pauciulo M, Wheeler L.

N Engl J Med. 2001 Aug 2;345(5):325-34.

8.

Distinct differences in gene expression patterns in pulmonary arteries of patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis with pulmonary hypertension.

Hoffmann J, Wilhelm J, Marsh LM, Ghanim B, Klepetko W, Kovacs G, Olschewski H, Olschewski A, Kwapiszewska G.

Am J Respir Crit Care Med. 2014 Jul 1;190(1):98-111. doi: 10.1164/rccm.201401-0037OC.

PMID:
24918967
9.

Endothelin-Bone morphogenetic protein type 2 receptor interaction induces pulmonary artery smooth muscle cell hyperplasia in pulmonary arterial hypertension.

Maruyama H, Dewachter C, Belhaj A, Rondelet B, Sakai S, Remmelink M, Vachiery JL, Naeije R, Dewachter L.

J Heart Lung Transplant. 2015 Mar;34(3):468-78. doi: 10.1016/j.healun.2014.09.011. Epub 2014 Sep 28.

PMID:
25447587
10.
11.

Lung tissues in patients with systemic sclerosis have gene expression patterns unique to pulmonary fibrosis and pulmonary hypertension.

Hsu E, Shi H, Jordan RM, Lyons-Weiler J, Pilewski JM, Feghali-Bostwick CA.

Arthritis Rheum. 2011 Mar;63(3):783-94. doi: 10.1002/art.30159.

12.

Endothelial-to-mesenchymal transition in pulmonary hypertension.

Ranchoux B, Antigny F, Rucker-Martin C, Hautefort A, Péchoux C, Bogaard HJ, Dorfmüller P, Remy S, Lecerf F, Planté S, Chat S, Fadel E, Houssaini A, Anegon I, Adnot S, Simonneau G, Humbert M, Cohen-Kaminsky S, Perros F.

Circulation. 2015 Mar 17;131(11):1006-18. doi: 10.1161/CIRCULATIONAHA.114.008750. Epub 2015 Jan 15.

13.

Involvement of the bone morphogenetic protein system in endothelin- and aldosterone-induced cell proliferation of pulmonary arterial smooth muscle cells isolated from human patients with pulmonary arterial hypertension.

Yamanaka R, Otsuka F, Nakamura K, Yamashita M, Otani H, Takeda M, Matsumoto Y, Kusano KF, Ito H, Makino H.

Hypertens Res. 2010 May;33(5):435-45. doi: 10.1038/hr.2010.16. Epub 2010 Feb 26.

PMID:
20186146
14.

Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension.

Morty RE, Nejman B, Kwapiszewska G, Hecker M, Zakrzewicz A, Kouri FM, Peters DM, Dumitrascu R, Seeger W, Knaus P, Schermuly RT, Eickelberg O.

Arterioscler Thromb Vasc Biol. 2007 May;27(5):1072-8. Epub 2007 Mar 8.

15.
16.

Genetic basis of pulmonary arterial hypertension: current understanding and future directions.

Newman JH, Trembath RC, Morse JA, Grunig E, Loyd JE, Adnot S, Coccolo F, Ventura C, Phillips JA 3rd, Knowles JA, Janssen B, Eickelberg O, Eddahibi S, Herve P, Nichols WC, Elliott G.

J Am Coll Cardiol. 2004 Jun 16;43(12 Suppl S):33S-39S. Review.

17.

Receptor for activated C-kinase 1, a novel interaction partner of type II bone morphogenetic protein receptor, regulates smooth muscle cell proliferation in pulmonary arterial hypertension.

Zakrzewicz A, Hecker M, Marsh LM, Kwapiszewska G, Nejman B, Long L, Seeger W, Schermuly RT, Morrell NW, Morty RE, Eickelberg O.

Circulation. 2007 Jun 12;115(23):2957-68. Epub 2007 May 21.

18.

Loss of bone morphogenetic protein receptor 2 is associated with abnormal DNA repair in pulmonary arterial hypertension.

Li M, Vattulainen S, Aho J, Orcholski M, Rojas V, Yuan K, Helenius M, Taimen P, Myllykangas S, De Jesus Perez V, Koskenvuo JW, Alastalo TP.

Am J Respir Cell Mol Biol. 2014 Jun;50(6):1118-28. doi: 10.1165/rcmb.2013-0349OC.

PMID:
24433082
19.
20.

Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity.

Liu D, Wang J, Kinzel B, Müeller M, Mao X, Valdez R, Liu Y, Li E.

Blood. 2007 Sep 1;110(5):1502-10. Epub 2007 May 11.

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