Similar articles for PMID: 20075161

Year	Number of Results
1993	1
1998	1
2000	1
2002	2
2007	4
2008	9
2009	5
2010	8
2011	6
2012	9
2013	4
2014	1
2015	4
2016	7
2017	7
2018	12
2019	11
2020	5
2021	6
2024	0

1

The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma.

Xu GW, Ali M, Wood TE, Wong D, Maclean N, Wang X, Gronda M, Skrtic M, Li X, Hurren R, Mao X, Venkatesan M, Beheshti Zavareh R, Ketela T, Reed JC, Rose D, Moffat J, Batey RA, Dhe-Paganon S, Schimmer AD. Xu GW, et al. Blood. 2010 Mar 18;115(11):2251-9. doi: 10.1182/blood-2009-07-231191. Epub 2010 Jan 14. Blood. 2010. PMID: 20075161 Free PMC article.

2

Design, synthesis, and biological evaluation of novel ubiquitin-activating enzyme inhibitors.

Itoh Y, Suzuki M. Itoh Y, et al. Bioorg Med Chem Lett. 2018 Sep 1;28(16):2723-2727. doi: 10.1016/j.bmcl.2018.03.004. Epub 2018 Mar 3. Bioorg Med Chem Lett. 2018. PMID: 29548576

3

Preclinical evaluation of the selective small-molecule UBA1 inhibitor, TAK-243, in acute myeloid leukemia.

Barghout SH, Patel PS, Wang X, Xu GW, Kavanagh S, Halgas O, Zarabi SF, Gronda M, Hurren R, Jeyaraju DV, MacLean N, Brennan S, Hyer ML, Berger A, Traore T, Milhollen M, Smith AC, Minden MD, Pai EF, Hakem R, Schimmer AD. Barghout SH, et al. Leukemia. 2019 Jan;33(1):37-51. doi: 10.1038/s41375-018-0167-0. Epub 2018 Jun 8. Leukemia. 2019. PMID: 29884901

4

Novel p97/VCP inhibitor induces endoplasmic reticulum stress and apoptosis in both bortezomib-sensitive and -resistant multiple myeloma cells.

Nishimura N, Radwan MO, Amano M, Endo S, Fujii E, Hayashi H, Ueno S, Ueno N, Tatetsu H, Hata H, Okamoto Y, Otsuka M, Mitsuya H, Matsuoka M, Okuno Y. Nishimura N, et al. Cancer Sci. 2019 Oct;110(10):3275-3287. doi: 10.1111/cas.14154. Epub 2019 Aug 14. Cancer Sci. 2019. PMID: 31368616 Free PMC article.

5

The ubiquitin-activating enzyme E1 as a novel therapeutic target for the treatment of restenosis.

Qin Z, Cui B, Jin J, Song M, Zhou B, Guo H, Qian D, He Y, Huang L. Qin Z, et al. Atherosclerosis. 2016 Apr;247:142-53. doi: 10.1016/j.atherosclerosis.2016.02.016. Epub 2016 Feb 13. Atherosclerosis. 2016. PMID: 26919560

6

Targeting the ubiquitin E1 as a novel anti-cancer strategy.

Xu W, Lukkarila JL, da Silva SR, Paiva SL, Gunning PT, Schimmer AD. Xu W, et al. Curr Pharm Des. 2013;19(18):3201-9. doi: 10.2174/1381612811319180004. Curr Pharm Des. 2013. PMID: 23151135 Review.

7

Identification and mechanistic studies of a novel ubiquitin E1 inhibitor.

Ungermannova D, Parker SJ, Nasveschuk CG, Chapnick DA, Phillips AJ, Kuchta RD, Liu X. Ungermannova D, et al. J Biomol Screen. 2012 Apr;17(4):421-34. doi: 10.1177/1087057111433843. Epub 2012 Jan 24. J Biomol Screen. 2012. PMID: 22274912 Free PMC article.

8

Ubiquitin-activating enzyme inhibition induces an unfolded protein response and overcomes drug resistance in myeloma.

Zhuang J, Shirazi F, Singh RK, Kuiatse I, Wang H, Lee HC, Berkova Z, Berger A, Hyer M, Chattopadhyay N, Syed S, Shi JQ, Yu J, Shinde V, Tirrell S, Jones RJ, Wang Z, Davis RE, Orlowski RZ. Zhuang J, et al. Blood. 2019 Apr 4;133(14):1572-1584. doi: 10.1182/blood-2018-06-859686. Epub 2019 Feb 8. Blood. 2019. PMID: 30737236 Free PMC article.

9

Nitric oxide prodrug JS-K inhibits ubiquitin E1 and kills tumor cells retaining wild-type p53.

Kitagaki J, Yang Y, Saavedra JE, Colburn NH, Keefer LK, Perantoni AO. Kitagaki J, et al. Oncogene. 2009 Jan 29;28(4):619-24. doi: 10.1038/onc.2008.401. Epub 2008 Nov 3. Oncogene. 2009. PMID: 18978812 Free PMC article.

10

Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme.

Li YJ, Du L, Wang J, Vega R, Lee TD, Miao Y, Aldana-Masangkay G, Samuels ER, Li B, Ouyang SX, Colayco SA, Bobkova EV, Divlianska DB, Sergienko E, Chung TDY, Fakih M, Chen Y. Li YJ, et al. Cell Chem Biol. 2019 Feb 21;26(2):278-288.e6. doi: 10.1016/j.chembiol.2018.10.026. Epub 2018 Dec 20. Cell Chem Biol. 2019. PMID: 30581133 Free PMC article.

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