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Items: 1 to 20 of 98

1.

A Combined Approach Using Patch-Clamp Study and Computer Simulation Study for Understanding Long QT Syndrome and TdP in Women.

Furukawa T, Kurokawa J, Clancy CE.

Curr Cardiol Rev. 2008 Nov;4(4):244-50. doi: 10.2174/157340308786349507.

2.

Progesterone regulates cardiac repolarization through a nongenomic pathway: an in vitro patch-clamp and computational modeling study.

Nakamura H, Kurokawa J, Bai CX, Asada K, Xu J, Oren RV, Zhu ZI, Clancy CE, Isobe M, Furukawa T.

Circulation. 2007 Dec 18;116(25):2913-22. Epub 2007 Dec 3.

3.

A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal-induced arrhythmias.

Yang PC, Perissinotti LL, López-Redondo F, Wang Y, DeMarco KR, Jeng MT, Vorobyov I, Harvey RD, Kurokawa J, Noskov SY, Clancy CE.

J Physiol. 2017 Jul 15;595(14):4695-4723. doi: 10.1113/JP273142. Epub 2017 Jun 14.

4.

Non-genomic action of sex steroid hormones and cardiac repolarization.

Kurokawa J, Furukawa T.

Biol Pharm Bull. 2013;36(1):8-12. Review.

5.

Antiarrhythmic properties of a rapid delayed-rectifier current activator in rabbit models of acquired long QT syndrome.

Diness TG, Yeh YH, Qi XY, Chartier D, Tsuji Y, Hansen RS, Olesen SP, Grunnet M, Nattel S.

Cardiovasc Res. 2008 Jul 1;79(1):61-9. doi: 10.1093/cvr/cvn075. Epub 2008 Mar 26.

PMID:
18367457
6.

Sex hormonal regulation of cardiac ion channels in drug-induced QT syndromes.

Kurokawa J, Kodama M, Clancy CE, Furukawa T.

Pharmacol Ther. 2016 Dec;168:23-28. doi: 10.1016/j.pharmthera.2016.09.004. Epub 2016 Sep 4. Review.

PMID:
27595633
7.

The morphology of the QT interval predicts torsade de pointes during acquired bradyarrhythmias.

Topilski I, Rogowski O, Rosso R, Justo D, Copperman Y, Glikson M, Belhassen B, Hochenberg M, Viskin S.

J Am Coll Cardiol. 2007 Jan 23;49(3):320-8. Epub 2007 Jan 4.

8.

Persistent atrial fibrillation is associated with reduced risk of torsades de pointes in patients with drug-induced long QT syndrome.

Darbar D, Kimbrough J, Jawaid A, McCray R, Ritchie MD, Roden DM.

J Am Coll Cardiol. 2008 Feb 26;51(8):836-42. doi: 10.1016/j.jacc.2007.09.066.

9.

Arrhythmia phenotype during fetal life suggests long-QT syndrome genotype: risk stratification of perinatal long-QT syndrome.

Cuneo BF, Etheridge SP, Horigome H, Sallee D, Moon-Grady A, Weng HY, Ackerman MJ, Benson DW.

Circ Arrhythm Electrophysiol. 2013 Oct;6(5):946-51. doi: 10.1161/CIRCEP.113.000618. Epub 2013 Aug 30.

10.

Cellular and ionic mechanism for drug-induced long QT syndrome and effectiveness of verapamil.

Aiba T, Shimizu W, Inagaki M, Noda T, Miyoshi S, Ding WG, Zankov DP, Toyoda F, Matsuura H, Horie M, Sunagawa K.

J Am Coll Cardiol. 2005 Jan 18;45(2):300-7.

11.
12.

Giant T-U waves precede torsades de pointes in long QT syndrome: a systematic electrocardiographic analysis in patients with acquired and congenital QT prolongation.

Kirchhof P, Franz MR, Bardai A, Wilde AM.

J Am Coll Cardiol. 2009 Jul 7;54(2):143-9. doi: 10.1016/j.jacc.2009.03.043.

13.

Sex differences in ventricular repolarization: from cardiac electrophysiology to Torsades de Pointes.

Abi-Gerges N, Philp K, Pollard C, Wakefield I, Hammond TG, Valentin JP.

Fundam Clin Pharmacol. 2004 Apr;18(2):139-51. Review.

PMID:
15066127
14.

Epidemiology of symptomatic drug-induced long QT syndrome and Torsade de Pointes in Germany.

Sarganas G, Garbe E, Klimpel A, Hering RC, Bronder E, Haverkamp W.

Europace. 2014 Jan;16(1):101-8. doi: 10.1093/europace/eut214. Epub 2013 Jul 5.

PMID:
23833046
15.

A new biomarker--index of cardiac electrophysiological balance (iCEB)--plays an important role in drug-induced cardiac arrhythmias: beyond QT-prolongation and Torsades de Pointes (TdPs).

Lu HR, Yan GX, Gallacher DJ.

J Pharmacol Toxicol Methods. 2013 Sep-Oct;68(2):250-9. doi: 10.1016/j.vascn.2013.01.003. Epub 2013 Jan 19.

PMID:
23337247
16.

Molecular predictors of drug-induced prolongation of the QT interval.

Dilaveris PE.

Curr Med Chem Cardiovasc Hematol Agents. 2005 Apr;3(2):105-18. Review.

PMID:
15853698
17.

The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT.

Mechakra A, Vincent Y, Chevalier P, Millat G, Ficker E, Jastrzebski M, Poulin H, Pouliot V, Chahine M, Christé G.

Gene. 2014 Feb 25;536(2):348-56. doi: 10.1016/j.gene.2013.11.072. Epub 2013 Dec 12.

PMID:
24334129
18.

Determinants of torsades de pointes in older patients with drug-associated long QT syndrome: a case-control study.

Goutelle S, Sidolle E, Ducher M, Caron J, Timour Q, Nony P, Gouraud A.

Drugs Aging. 2014 Aug;31(8):601-9. doi: 10.1007/s40266-014-0188-y.

PMID:
24923384
20.

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