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Items: 1 to 20 of 200

1.

Mechanisms of oxidative glutamate toxicity: the glutamate/cystine antiporter system xc- as a neuroprotective drug target.

Albrecht P, Lewerenz J, Dittmer S, Noack R, Maher P, Methner A.

CNS Neurol Disord Drug Targets. 2010 Jul;9(3):373-82. Review.

PMID:
20053169
2.
4.

Distribution of the cystine/glutamate antiporter system xc- in the brain, kidney, and duodenum.

Burdo J, Dargusch R, Schubert D.

J Histochem Cytochem. 2006 May;54(5):549-57. Epub 2006 Jan 6.

PMID:
16399997
5.

Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation.

Shih AY, Erb H, Sun X, Toda S, Kalivas PW, Murphy TH.

J Neurosci. 2006 Oct 11;26(41):10514-23.

6.

Oxidative glutamate toxicity can be a component of the excitotoxicity cascade.

Schubert D, Piasecki D.

J Neurosci. 2001 Oct 1;21(19):7455-62.

7.

The oxidative stress-inducible cystine/glutamate antiporter, system x (c) (-) : cystine supplier and beyond.

Conrad M, Sato H.

Amino Acids. 2012 Jan;42(1):231-46. doi: 10.1007/s00726-011-0867-5. Epub 2011 Mar 16. Review.

PMID:
21409388
8.

beta-N-methylamino-l-alanine induces oxidative stress and glutamate release through action on system Xc(-).

Liu X, Rush T, Zapata J, Lobner D.

Exp Neurol. 2009 Jun;217(2):429-33. doi: 10.1016/j.expneurol.2009.04.002. Epub 2009 Apr 15.

PMID:
19374900
9.

Distinct nuclear factor-kappaB/Rel proteins have opposing modulatory effects in glutamate-induced cell death in HT22 cells.

Ishige K, Tanaka M, Arakawa M, Saito H, Ito Y.

Neurochem Int. 2005 Dec;47(8):545-55. Epub 2005 Sep 22.

PMID:
16183169
10.

Expression and developmental regulation of the cystine/glutamate exchanger (xc-) in the rat.

La Bella V, Valentino F, Piccoli T, Piccoli F.

Neurochem Res. 2007 Jun;32(6):1081-90. Epub 2007 Mar 31.

PMID:
17401668
11.

Melatonin prevents glutamate-induced oxytosis in the HT22 mouse hippocampal cell line through an antioxidant effect specifically targeting mitochondria.

Herrera F, Martin V, García-Santos G, Rodriguez-Blanco J, Antolín I, Rodriguez C.

J Neurochem. 2007 Feb;100(3):736-46.

12.

Regulation of xCT expression and system x (c) (-) function in neuronal cells.

Lewerenz J, Maher P, Methner A.

Amino Acids. 2012 Jan;42(1):171-9. doi: 10.1007/s00726-011-0862-x. Epub 2011 Mar 3. Review.

PMID:
21369940
13.
14.

Oxytosis: A novel form of programmed cell death.

Tan S, Schubert D, Maher P.

Curr Top Med Chem. 2001 Dec;1(6):497-506. Review.

PMID:
11895126
15.

Reactive oxygen species involved in the glutamate toxicity of C6 glioma cells via xc antiporter system.

Mawatari K, Yasui Y, Sugitani K, Takadera T, Kato S.

Neuroscience. 1996 Jul;73(1):201-8.

PMID:
8783242
16.
17.

Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.

Massie A, Schallier A, Kim SW, Fernando R, Kobayashi S, Beck H, De Bundel D, Vermoesen K, Bannai S, Smolders I, Conrad M, Plesnila N, Sato H, Michotte Y.

FASEB J. 2011 Apr;25(4):1359-69. doi: 10.1096/fj.10-177212. Epub 2010 Dec 29.

PMID:
21191088
18.

Loss of system x(c)- does not induce oxidative stress but decreases extracellular glutamate in hippocampus and influences spatial working memory and limbic seizure susceptibility.

De Bundel D, Schallier A, Loyens E, Fernando R, Miyashita H, Van Liefferinge J, Vermoesen K, Bannai S, Sato H, Michotte Y, Smolders I, Massie A.

J Neurosci. 2011 Apr 13;31(15):5792-803. doi: 10.1523/JNEUROSCI.5465-10.2011.

19.

The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death.

Banjac A, Perisic T, Sato H, Seiler A, Bannai S, Weiss N, Kölle P, Tschoep K, Issels RD, Daniel PT, Conrad M, Bornkamm GW.

Oncogene. 2008 Mar 6;27(11):1618-28. Epub 2007 Sep 10.

PMID:
17828297
20.

Glutamate, excitatory amino acid transporters, Xc- antiporter, glutamine synthetase, and gamma-glutamyltranspeptidase in human corneal epithelium.

Langford MP, Redmond P, Chanis R, Misra RP, Redens TB.

Curr Eye Res. 2010 Mar;35(3):202-11. doi: 10.3109/02713680903461489.

PMID:
20373878

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