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Items: 1 to 20 of 104

1.

Detoxication of sulfur half-mustards by nucleophilic scavengers: robust activity of thiopurines.

Liu J, Powell KL, Thames HD, MacLeod MC.

Chem Res Toxicol. 2010 Mar 15;23(3):488-96. doi: 10.1021/tx900190j.

2.

2,6-Dithiopurine blocks toxicity and mutagenesis in human skin cells exposed to sulfur mustard analogues, 2-chloroethyl ethyl sulfide and 2-chloroethyl methyl sulfide.

Powell KL, Boulware S, Thames H, Vasquez KM, MacLeod MC.

Chem Res Toxicol. 2010 Mar 15;23(3):497-503. doi: 10.1021/tx9001918.

3.

2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog.

Boulware S, Fields T, McIvor E, Powell KL, Abel EL, Vasquez KM, MacLeod MC.

Toxicol Appl Pharmacol. 2012 Sep 1;263(2):203-9. doi: 10.1016/j.taap.2012.06.010. Epub 2012 Jun 23.

4.

Sulfur, oxygen, and nitrogen mustards: stability and reactivity.

Wang QQ, Begum RA, Day VW, Bowman-James K.

Org Biomol Chem. 2012 Nov 28;10(44):8786-93. doi: 10.1039/c2ob26482j.

PMID:
23070251
5.

Direct binding of sulfur mustard and chloroethyl ethyl sulphide to human cell membrane-associated proteins; implications for sulfur mustard pathology.

Sayer NM, Whiting R, Green AC, Anderson K, Jenner J, Lindsay CD.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 May 15;878(17-18):1426-32. doi: 10.1016/j.jchromb.2009.11.030. Epub 2009 Nov 18.

PMID:
20004628
6.
7.

Modified immunoslotblot assay to detect hemi and sulfur mustard DNA adducts.

Kehe K, Schrettl V, Thiermann H, Steinritz D.

Chem Biol Interact. 2013 Dec 5;206(3):523-8. doi: 10.1016/j.cbi.2013.08.001. Epub 2013 Aug 8.

PMID:
23933409
8.

Sulforaphane induces phase II detoxication enzymes in mouse skin and prevents mutagenesis induced by a mustard gas analog.

Abel EL, Boulware S, Fields T, McIvor E, Powell KL, DiGiovanni J, Vasquez KM, MacLeod MC.

Toxicol Appl Pharmacol. 2013 Feb 1;266(3):439-42. doi: 10.1016/j.taap.2012.11.020. Epub 2012 Nov 30.

9.

Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences.

Mangerich A, Debiak M, Birtel M, Ponath V, Balszuweit F, Lex K, Martello R, Burckhardt-Boer W, Strobelt R, Siegert M, Thiermann H, Steinritz D, Schmidt A, Bürkle A.

Toxicol Lett. 2016 Feb 26;244:56-71. doi: 10.1016/j.toxlet.2015.09.010. Epub 2015 Sep 14.

PMID:
26383629
10.

Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway.

Abel EL, Bubel JD, Simper MS, Powell L, McClellan SA, Andreeff M, MacLeod MC, DiGiovanni J.

Toxicol Appl Pharmacol. 2011 Sep 1;255(2):176-83. doi: 10.1016/j.taap.2011.06.012. Epub 2011 Jun 23.

PMID:
21723306
13.

Toxicology and pharmacology of the chemical warfare agent sulfur mustard.

Dacre JC, Goldman M.

Pharmacol Rev. 1996 Jun;48(2):289-326. Review.

PMID:
8804107
14.

A simple and economical chemical neutralization method for the destruction of sulfur mustard and its analogues.

Gupta AK, Dubey DK, Kaushik MP.

J Hazard Mater. 2007 Jan 2;139(1):154-9. Epub 2006 Jun 10.

PMID:
16846683
15.

Applying human and pig hepatic in vitro experiments for sulfur mustard study: screening and identification of metabolites by liquid chromatography/tandem mass spectrometry.

Halme M, Pesonen M, Hakala U, Pasanen M, Vähäkangas K, Vanninen P.

Rapid Commun Mass Spectrom. 2015 Jul 30;29(14):1279-87. doi: 10.1002/rcm.7218.

PMID:
26405789
16.

Free radical production from the interaction of 2-chloroethyl vesicants (mustard gas) with pyridine nucleotide-driven flavoprotein electron transport systems.

Brimfield AA, Mancebo AM, Mason RP, Jiang JJ, Siraki AG, Novak MJ.

Toxicol Appl Pharmacol. 2009 Jan 1;234(1):128-34. doi: 10.1016/j.taap.2008.10.002. Epub 2008 Oct 15.

17.

Fungal cleavage of thioether bond found in Yperite.

Itoh N, Yoshida M, Miyamoto T, Ichinose H, Wariishi H, Tanaka H.

FEBS Lett. 1997 Jul 28;412(2):281-4.

18.

Detoxification of sulfur mustard by enzyme-catalyzed oxidation using chloroperoxidase.

Popiel S, Nawała J.

Enzyme Microb Technol. 2013 Oct 10;53(5):295-301. doi: 10.1016/j.enzmictec.2013.06.002. Epub 2013 Jul 5.

PMID:
24034427
19.

Mass spectral behavior of the hydrolysis products of sesqui- and oxy-mustard type chemical warfare agents in atmospheric pressure chemical ionization.

Lemire SW, Ash DH, Johnson RC, Barr JR.

J Am Soc Mass Spectrom. 2007 Aug;18(8):1364-74. Epub 2007 Apr 29.

20.

Screening hydrolysis products of sulfur mustard agents by high-performance liquid chromatography with inductively coupled plasma mass spectrometry detection.

Kroening KK, Richardson DD, Afton S, Caruso JA.

Anal Bioanal Chem. 2009 Apr;393(8):1949-56. doi: 10.1007/s00216-009-2642-y. Epub 2009 Feb 12.

PMID:
19214483

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