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Items: 1 to 20 of 140

1.

Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases.

Liu PQ, Chan EM, Cost GJ, Zhang L, Wang J, Miller JC, Guschin DY, Reik A, Holmes MC, Mott JE, Collingwood TN, Gregory PD.

Biotechnol Bioeng. 2010 May 1;106(1):97-105. doi: 10.1002/bit.22654.

PMID:
20047187
2.

Highly efficient deletion of FUT8 in CHO cell lines using zinc-finger nucleases yields cells that produce completely nonfucosylated antibodies.

Malphettes L, Freyvert Y, Chang J, Liu PQ, Chan E, Miller JC, Zhou Z, Nguyen T, Tsai C, Snowden AW, Collingwood TN, Gregory PD, Cost GJ.

Biotechnol Bioeng. 2010 Aug 1;106(5):774-83. doi: 10.1002/bit.22751.

PMID:
20564614
3.

Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases.

Watanabe M, Umeyama K, Matsunari H, Takayanagi S, Haruyama E, Nakano K, Fujiwara T, Ikezawa Y, Nakauchi H, Nagashima H.

Biochem Biophys Res Commun. 2010 Nov 5;402(1):14-8. doi: 10.1016/j.bbrc.2010.09.092. Epub 2010 Sep 26.

PMID:
20875794
4.

Design and testing of zinc finger nucleases for use in mammalian cells.

Porteus M.

Methods Mol Biol. 2008;435:47-61. doi: 10.1007/978-1-59745-232-8_4.

PMID:
18370067
5.

Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells.

Fan L, Kadura I, Krebs LE, Hatfield CC, Shaw MM, Frye CC.

Biotechnol Bioeng. 2012 Apr;109(4):1007-15. doi: 10.1002/bit.24365. Epub 2011 Nov 21.

PMID:
22068567
6.

Gene targeting using zinc finger nucleases.

Porteus MH, Carroll D.

Nat Biotechnol. 2005 Aug;23(8):967-73. Review.

PMID:
16082368
7.

Targeted genome editing in pluripotent stem cells using zinc-finger nucleases.

Bobis-Wozowicz S, Osiak A, Rahman SH, Cathomen T.

Methods. 2011 Apr;53(4):339-46. doi: 10.1016/j.ymeth.2010.12.019. Epub 2010 Dec 23.

PMID:
21185378
8.

Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.

Santiago Y, Chan E, Liu PQ, Orlando S, Zhang L, Urnov FD, Holmes MC, Guschin D, Waite A, Miller JC, Rebar EJ, Gregory PD, Klug A, Collingwood TN.

Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5809-14. doi: 10.1073/pnas.0800940105. Epub 2008 Mar 21.

9.

Creating zinc finger nucleases to manipulate the genome in a site-specific manner using a modular-assembly approach.

Porteus M.

Cold Spring Harb Protoc. 2010 Dec 1;2010(12):pdb.top93. doi: 10.1101/pdb.top93.

PMID:
21123434
10.

Generation of gene-specific mutated rats using zinc-finger nucleases.

Geurts AM, Cost GJ, Rémy S, Cui X, Tesson L, Usal C, Ménoret S, Jacob HJ, Anegon I, Buelow R.

Methods Mol Biol. 2010;597:211-25. doi: 10.1007/978-1-60327-389-3_15.

PMID:
20013236
11.

Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases.

Hauschild J, Petersen B, Santiago Y, Queisser AL, Carnwath JW, Lucas-Hahn A, Zhang L, Meng X, Gregory PD, Schwinzer R, Cost GJ, Niemann H.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12013-7. doi: 10.1073/pnas.1106422108. Epub 2011 Jul 5. Erratum in: Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):15010.

12.

Cellular responses to targeted genomic sequence modification using single-stranded oligonucleotides and zinc-finger nucleases.

Olsen PA, Solhaug A, Booth JA, Gelazauskaite M, Krauss S.

DNA Repair (Amst). 2009 Mar 1;8(3):298-308. doi: 10.1016/j.dnarep.2008.11.011. Epub 2008 Dec 30.

PMID:
19071233
13.

Genome editing with CompoZr custom zinc finger nucleases (ZFNs).

Hansen K, Coussens MJ, Sago J, Subramanian S, Gjoka M, Briner D.

J Vis Exp. 2012 Jun 14;(64):e3304. doi: 10.3791/3304.

14.

Creating zinc finger nucleases using a modular-assembly approach.

Porteus M.

Cold Spring Harb Protoc. 2010 Dec 1;2010(12):pdb.prot5530. doi: 10.1101/pdb.prot5530.

PMID:
21123417
15.

Efficient immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases.

Flisikowska T, Thorey IS, Offner S, Ros F, Lifke V, Zeitler B, Rottmann O, Vincent A, Zhang L, Jenkins S, Niersbach H, Kind AJ, Gregory PD, Schnieke AE, Platzer J.

PLoS One. 2011;6(6):e21045. doi: 10.1371/journal.pone.0021045. Epub 2011 Jun 13.

16.

Gene targeting in Drosophila and Caenorhabditis elegans with zinc-finger nucleases.

Carroll D, Beumer KJ, Morton JJ, Bozas A, Trautman JK.

Methods Mol Biol. 2008;435:63-77. doi: 10.1007/978-1-59745-232-8_5.

PMID:
18370068
17.

Biallelic knockout of the α-1,3 galactosyltransferase gene in porcine liver-derived cells using zinc finger nucleases.

Li P, Estrada JL, Burlak C, Tector AJ.

J Surg Res. 2013 May 1;181(1):e39-45. doi: 10.1016/j.jss.2012.06.035. Epub 2012 Jul 3.

PMID:
22795272
18.

Critical parameters for genome editing using zinc finger nucleases.

Camenisch TD, Brilliant MH, Segal DJ.

Mini Rev Med Chem. 2008 Jun;8(7):669-76. Review.

PMID:
18537722
19.

Selection-independent generation of gene knockout mouse embryonic stem cells using zinc-finger nucleases.

Osiak A, Radecke F, Guhl E, Radecke S, Dannemann N, Lütge F, Glage S, Rudolph C, Cantz T, Schwarz K, Heilbronn R, Cathomen T.

PLoS One. 2011;6(12):e28911. doi: 10.1371/journal.pone.0028911. Epub 2011 Dec 14.

20.

Testing a three-finger zinc finger nuclease using a GFP reporter system.

Porteus M.

Cold Spring Harb Protoc. 2010 Dec 1;2010(12):pdb.prot5531. doi: 10.1101/pdb.prot5531.

PMID:
21123418

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