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Items: 1 to 20 of 118

1.

Loss of hepatocyte nuclear factor 1alpha function in human hepatocellular adenomas leads to aberrant activation of signaling pathways involved in tumorigenesis.

Pelletier L, Rebouissou S, Paris A, Rathahao-Paris E, Perdu E, Bioulac-Sage P, Imbeaud S, Zucman-Rossi J.

Hepatology. 2010 Feb;51(2):557-66. doi: 10.1002/hep.23362.

PMID:
20041408
2.

HNF1α inhibition triggers epithelial-mesenchymal transition in human liver cancer cell lines.

Pelletier L, Rebouissou S, Vignjevic D, Bioulac-Sage P, Zucman-Rossi J.

BMC Cancer. 2011 Oct 5;11:427. doi: 10.1186/1471-2407-11-427.

3.

HNF1alpha inactivation promotes lipogenesis in human hepatocellular adenoma independently of SREBP-1 and carbohydrate-response element-binding protein (ChREBP) activation.

Rebouissou S, Imbeaud S, Balabaud C, Boulanger V, Bertrand-Michel J, Tercé F, Auffray C, Bioulac-Sage P, Zucman-Rossi J.

J Biol Chem. 2007 May 11;282(19):14437-46. Epub 2007 Mar 22.

4.

Association of CYP1B1 germ line mutations with hepatocyte nuclear factor 1alpha-mutated hepatocellular adenoma.

Jeannot E, Poussin K, Chiche L, Bacq Y, Sturm N, Scoazec JY, Buffet C, Van Nhieu JT, Bellanné-Chantelot C, de Toma C, Laurent-Puig P, Bioulac-Sage P, Zucman-Rossi J.

Cancer Res. 2007 Mar 15;67(6):2611-6.

5.

Molecular characterization of hepatocellular adenomas developed in patients with glycogen storage disease type I.

Calderaro J, Labrune P, Morcrette G, Rebouissou S, Franco D, Prévot S, Quaglia A, Bedossa P, Libbrecht L, Terracciano L, Smit GP, Bioulac-Sage P, Zucman-Rossi J.

J Hepatol. 2013 Feb;58(2):350-7. doi: 10.1016/j.jhep.2012.09.030. Epub 2012 Oct 6.

PMID:
23046672
6.

MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations.

Ladeiro Y, Couchy G, Balabaud C, Bioulac-Sage P, Pelletier L, Rebouissou S, Zucman-Rossi J.

Hepatology. 2008 Jun;47(6):1955-63. doi: 10.1002/hep.22256.

7.

Subtype classification of hepatocellular adenoma.

Bioulac-Sage P, Balabaud C, Zucman-Rossi J.

Dig Surg. 2010;27(1):39-45. doi: 10.1159/000268406. Epub 2010 Apr 1.

8.

Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry.

Bioulac-Sage P, Rebouissou S, Thomas C, Blanc JF, Saric J, Sa Cunha A, Rullier A, Cubel G, Couchy G, Imbeaud S, Balabaud C, Zucman-Rossi J.

Hepatology. 2007 Sep;46(3):740-8.

PMID:
17663417
9.

Hepatocellular adenoma management and phenotypic classification: the Bordeaux experience.

Bioulac-Sage P, Laumonier H, Couchy G, Le Bail B, Sa Cunha A, Rullier A, Laurent C, Blanc JF, Cubel G, Trillaud H, Zucman-Rossi J, Balabaud C, Saric J.

Hepatology. 2009 Aug;50(2):481-9. doi: 10.1002/hep.22995.

PMID:
19585623
10.

Chromosomal and genetic alterations in human hepatocellular adenomas associated with type Ia glycogen storage disease.

Kishnani PS, Chuang TP, Bali D, Koeberl D, Austin S, Weinstein DA, Murphy E, Chen YT, Boyette K, Liu CH, Chen YT, Li LH.

Hum Mol Genet. 2009 Dec 15;18(24):4781-90. doi: 10.1093/hmg/ddp441. Epub 2009 Sep 16.

PMID:
19762333
11.

Spectrum of HNF1A somatic mutations in hepatocellular adenoma differs from that in patients with MODY3 and suggests genotoxic damage.

Jeannot E, Mellottee L, Bioulac-Sage P, Balabaud C, Scoazec JY, Tran Van Nhieu J, Bacq Y, Michalak S, Buob D; Groupe d'étude Génétique des Tumeurs Hépatiques (INSERM Network), Laurent-Puig P, Rusyn I, Zucman-Rossi J.

Diabetes. 2010 Jul;59(7):1836-44. doi: 10.2337/db09-1819. Epub 2010 Apr 14.

12.

Unique genetic alterations and clinicopathological features of hepatocellular adenoma in Chinese population.

Liu HP, Zhao Q, Jin GZ, Qian YW, Gu YJ, Dong H, Lu XY, Cong WM, Wu MC.

Pathol Res Pract. 2015 Dec;211(12):918-24. doi: 10.1016/j.prp.2015.09.003. Epub 2015 Sep 7.

PMID:
26608415
13.

Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation.

Nault JC, Couchy G, Balabaud C, Morcrette G, Caruso S, Blanc JF, Bacq Y, Calderaro J, Paradis V, Ramos J, Scoazec JY, Gnemmi V, Sturm N, Guettier C, Fabre M, Savier E, Chiche L, Labrune P, Selves J, Wendum D, Pilati C, Laurent A, De Muret A, Le Bail B, Rebouissou S, Imbeaud S; GENTHEP Investigators, Bioulac-Sage P, Letouzé E, Zucman-Rossi J.

Gastroenterology. 2017 Mar;152(4):880-894.e6. doi: 10.1053/j.gastro.2016.11.042. Epub 2016 Dec 7.

PMID:
27939373
14.

Genotype-phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC.

Zucman-Rossi J, Jeannot E, Nhieu JT, Scoazec JY, Guettier C, Rebouissou S, Bacq Y, Leteurtre E, Paradis V, Michalak S, Wendum D, Chiche L, Fabre M, Mellottee L, Laurent C, Partensky C, Castaing D, Zafrani ES, Laurent-Puig P, Balabaud C, Bioulac-Sage P.

Hepatology. 2006 Mar;43(3):515-24.

PMID:
16496320
15.

New monoallelic (partial tandem duplication) mutation of HNF1a gene in steatotic hepatocellular adenoma.

Sakellariou S, Morgan Y, Heaton N, Portmann B, Quaglia A, Tobal K.

Eur J Gastroenterol Hepatol. 2011 Jul;23(7):623-7. doi: 10.1097/MEG.0b013e328347964d.

PMID:
21566527
16.

Primary hepatocellular neoplasms in a MODY3 family with a novel HNF1A germline mutation.

Willson JS, Godwin TD, Wiggins GA, Guilford PJ, McCall JL.

J Hepatol. 2013 Oct;59(4):904-7. doi: 10.1016/j.jhep.2013.05.024. Epub 2013 May 23.

17.

Mutation of TCF1 encoding hepatocyte nuclear factor 1alpha in gynecological cancer.

Rebouissou S, Rosty C, Lecuru F, Boisselier S, Bui H, Le Frere-Belfa MA, Sastre X, Laurent-Puig P, Zucman-Rossi J.

Oncogene. 2004 Sep 30;23(45):7588-92.

PMID:
15326484
18.

Germline hepatocyte nuclear factor 1alpha and 1beta mutations in renal cell carcinomas.

Rebouissou S, Vasiliu V, Thomas C, Bellanné-Chantelot C, Bui H, Chrétien Y, Timsit J, Rosty C, Laurent-Puig P, Chauveau D, Zucman-Rossi J.

Hum Mol Genet. 2005 Mar 1;14(5):603-14. Epub 2005 Jan 13.

PMID:
15649945
19.

Coexistence of inflammatory hepatocellular adenomas with HNF1α-inactivated adenomas: is there an association?

Castain C, Sempoux C, Brunt EM, Causse O, Heitzmann A, Hernandez-Prera JC, Le Bail B, Schirmacher P, Thung SN, Balabaud C, Bioulac-Sage P.

Histopathology. 2014 May;64(6):890-5. doi: 10.1111/his.12326. Epub 2014 Jan 24.

PMID:
24236804
20.

Molecular pathogenesis of focal nodular hyperplasia and hepatocellular adenoma.

Rebouissou S, Bioulac-Sage P, Zucman-Rossi J.

J Hepatol. 2008 Jan;48(1):163-70. Epub 2007 Oct 30. Review.

PMID:
17997499

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