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Items: 1 to 20 of 197

1.

SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression.

Mleczko-Sanecka K, Casanovas G, Ragab A, Breitkopf K, Müller A, Boutros M, Dooley S, Hentze MW, Muckenthaler MU.

Blood. 2010 Apr 1;115(13):2657-65. doi: 10.1182/blood-2009-09-238105. Epub 2009 Dec 29.

2.

STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation.

Verga Falzacappa MV, Vujic Spasic M, Kessler R, Stolte J, Hentze MW, Muckenthaler MU.

Blood. 2007 Jan 1;109(1):353-8. Epub 2006 Aug 31.

3.

Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD.

Casanovas G, Mleczko-Sanecka K, Altamura S, Hentze MW, Muckenthaler MU.

J Mol Med (Berl). 2009 May;87(5):471-80. doi: 10.1007/s00109-009-0447-2. Epub 2009 Feb 20.

PMID:
19229506
4.

A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells.

Verga Falzacappa MV, Casanovas G, Hentze MW, Muckenthaler MU.

J Mol Med (Berl). 2008 May;86(5):531-40. doi: 10.1007/s00109-008-0313-7. Epub 2008 Apr 18.

PMID:
18421430
5.
6.

Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6.

Truksa J, Gelbart T, Peng H, Beutler E, Beutler B, Lee P.

Br J Haematol. 2009 Nov;147(4):571-81. doi: 10.1111/j.1365-2141.2009.07873.x. Epub 2009 Sep 8.

PMID:
19751239
7.

Smad7 mediates inhibition of Saos2 osteosarcoma cell differentiation by NFkappaB.

Eliseev RA, Schwarz EM, Zuscik MJ, O'Keefe RJ, Drissi H, Rosier RN.

Exp Cell Res. 2006 Jan 1;312(1):40-50. Epub 2005 Nov 2.

PMID:
16259979
8.

Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation.

Zhang S, Fei T, Zhang L, Zhang R, Chen F, Ning Y, Han Y, Feng XH, Meng A, Chen YG.

Mol Cell Biol. 2007 Jun;27(12):4488-99. Epub 2007 Apr 16.

9.

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver.

Kautz L, Meynard D, Monnier A, Darnaud V, Bouvet R, Wang RH, Deng C, Vaulont S, Mosser J, Coppin H, Roth MP.

Blood. 2008 Aug 15;112(4):1503-9. doi: 10.1182/blood-2008-03-143354. Epub 2008 Jun 6.

10.

Interacting signals in the control of hepcidin expression.

Darshan D, Anderson GJ.

Biometals. 2009 Feb;22(1):77-87. doi: 10.1007/s10534-008-9187-y. Epub 2009 Jan 8.

PMID:
19130266
11.

Iron-induced expression of bone morphogenic protein 6 in intestinal cells is the main regulator of hepatic hepcidin expression in vivo.

Arndt S, Maegdefrau U, Dorn C, Schardt K, Hellerbrand C, Bosserhoff AK.

Gastroenterology. 2010 Jan;138(1):372-82. doi: 10.1053/j.gastro.2009.09.048. Epub 2009 Sep 26.

PMID:
19786029
12.
13.

Oncostatin M is a potent inducer of hepcidin, the iron regulatory hormone.

Chung B, Verdier F, Matak P, Deschemin JC, Mayeux P, Vaulont S.

FASEB J. 2010 Jun;24(6):2093-103. doi: 10.1096/fj.09-152561. Epub 2010 Feb 2.

PMID:
20124431
14.

Hemojuvelin: the hepcidin story continues.

Malyszko J.

Kidney Blood Press Res. 2009;32(2):71-6. doi: 10.1159/000208988. Epub 2009 Mar 14. Review.

15.

SnoN co-repressor binds and represses smad7 gene promoter.

Briones-Orta MA, Sosa-Garrocho M, Moreno-Alvarez P, Fonseca-Sánchez MA, Macías-Silva M.

Biochem Biophys Res Commun. 2006 Mar 17;341(3):889-94. Epub 2006 Jan 23.

PMID:
16442497
16.

Transcriptional regulation of Smad2 is required for enhancement of TGFbeta/Smad signaling by TGFbeta inducible early gene.

Johnsen SA, Subramaniam M, Katagiri T, Janknecht R, Spelsberg TC.

J Cell Biochem. 2002;87(2):233-41.

PMID:
12244575
17.

Regulation of TGF-beta signaling by Smad7.

Yan X, Liu Z, Chen Y.

Acta Biochim Biophys Sin (Shanghai). 2009 Apr;41(4):263-72. Review.

19.

Hepcidin, a key regulator of iron metabolism, is transcriptionally activated by p53.

Weizer-Stern O, Adamsky K, Margalit O, Ashur-Fabian O, Givol D, Amariglio N, Rechavi G.

Br J Haematol. 2007 Jul;138(2):253-62.

PMID:
17593032
20.

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