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Items: 1 to 20 of 54


Modulation of canine cardiac sodium current by Apelin.

Chamberland C, Barajas-Martinez H, Haufe V, Fecteau MH, Delabre JF, Burashnikov A, Antzelevitch C, Lesur O, Chraibi A, Sarret P, Dumaine R.

J Mol Cell Cardiol. 2010 Apr;48(4):694-701. doi: 10.1016/j.yjmcc.2009.12.011. Epub 2009 Dec 28.


Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility.

Szokodi I, Tavi P, Földes G, Voutilainen-Myllylä S, Ilves M, Tokola H, Pikkarainen S, Piuhola J, Rysä J, Tóth M, Ruskoaho H.

Circ Res. 2002 Sep 6;91(5):434-40.


Larger dispersion of INa in female dog ventricle as a mechanism for gender-specific incidence of cardiac arrhythmias.

Barajas-Martinez H, Haufe V, Chamberland C, Roy MJ, Fecteau MH, Cordeiro JM, Dumaine R.

Cardiovasc Res. 2009 Jan 1;81(1):82-9. doi: 10.1093/cvr/cvn255. Epub 2008 Sep 18.


Re-evaluation of the action potential upstroke velocity as a measure of the Na+ current in cardiac myocytes at physiological conditions.

Berecki G, Wilders R, de Jonge B, van Ginneken AC, Verkerk AO.

PLoS One. 2010 Dec 31;5(12):e15772. doi: 10.1371/journal.pone.0015772.


Direct effects of apelin on cardiomyocyte contractility and electrophysiology.

Farkasfalvi K, Stagg MA, Coppen SR, Siedlecka U, Lee J, Soppa GK, Marczin N, Szokodi I, Yacoub MH, Terracciano CM.

Biochem Biophys Res Commun. 2007 Jun 15;357(4):889-95. Epub 2007 Apr 12.


Cardiac resynchronization therapy improves altered Na channel gating in canine model of dyssynchronous heart failure.

Aiba T, Barth AS, Hesketh GG, Hashambhoy YL, Chakir K, Tunin RS, Greenstein JL, Winslow RL, Kass DA, Tomaselli GF.

Circ Arrhythm Electrophysiol. 2013 Jun;6(3):546-54. doi: 10.1161/CIRCEP.113.000400. Epub 2013 May 6.


Actions of pyrethroid insecticides on sodium currents, action potentials, and contractile rhythm in isolated mammalian ventricular myocytes and perfused hearts.

Spencer CI, Yuill KH, Borg JJ, Hancox JC, Kozlowski RZ.

J Pharmacol Exp Ther. 2001 Sep;298(3):1067-82. Erratum in: J Pharmacol Exp Ther 2001 Oct;299(1):399.


Na-Ca exchange tail current indicates voltage dependence of the Cai transient in rabbit ventricular myocytes.

Hancox JC, Levi AJ.

J Cardiovasc Electrophysiol. 1995 Jun;6(6):455-70.


Assessing use-dependent inhibition of the cardiac Na(+/-) current (I(Na)) in the PatchXpress automated patch clamp.

Penniman JR, Kim DC, Salata JJ, Imredy JP.

J Pharmacol Toxicol Methods. 2010 Sep-Oct;62(2):107-18. doi: 10.1016/j.vascn.2010.06.007. Epub 2010 Jun 22.


Modulation of late sodium current by Ca2+, calmodulin, and CaMKII in normal and failing dog cardiomyocytes: similarities and differences.

Maltsev VA, Reznikov V, Undrovinas NA, Sabbah HN, Undrovinas A.

Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1597-608. doi: 10.1152/ajpheart.00484.2007. Epub 2008 Jan 18.


Electrophysiological effects of protopine in cardiac myocytes: inhibition of multiple cation channel currents.

Song LS, Ren GJ, Chen ZL, Chen ZH, Zhou ZN, Cheng H.

Br J Pharmacol. 2000 Mar;129(5):893-900.


About half of the late sodium current in cardiac myocytes from dog ventricle is due to non-cardiac-type Na(+) channels.

Biet M, Barajas-Martínez H, Ton AT, Delabre JF, Morin N, Dumaine R.

J Mol Cell Cardiol. 2012 Nov;53(5):593-8. doi: 10.1016/j.yjmcc.2012.06.012. Epub 2012 Jun 30.


Functionally distinct sodium channels in ventricular epicardial and endocardial cells contribute to a greater sensitivity of the epicardium to electrical depression.

Cordeiro JM, Mazza M, Goodrow R, Ulahannan N, Antzelevitch C, Di Diego JM.

Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H154-62. doi: 10.1152/ajpheart.01327.2007. Epub 2008 May 2.


Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.

Yuan L, Koivumäki JT, Liang B, Lorentzen LG, Tang C, Andersen MN, Svendsen JH, Tfelt-Hansen J, Maleckar M, Schmitt N, Olesen MS, Jespersen T.

Am J Physiol Heart Circ Physiol. 2014 Apr 15;306(8):H1204-12. doi: 10.1152/ajpheart.00405.2013. Epub 2014 Feb 21.


14-3-3 is a regulator of the cardiac voltage-gated sodium channel Nav1.5.

Allouis M, Le Bouffant F, Wilders R, Péroz D, Schott JJ, Noireaud J, Le Marec H, Mérot J, Escande D, Baró I.

Circ Res. 2006 Jun 23;98(12):1538-46. Epub 2006 May 25.


The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo.

Ashley EA, Powers J, Chen M, Kundu R, Finsterbach T, Caffarelli A, Deng A, Eichhorn J, Mahajan R, Agrawal R, Greve J, Robbins R, Patterson AJ, Bernstein D, Quertermous T.

Cardiovasc Res. 2005 Jan 1;65(1):73-82.


Rapid onset of lysophosphatidylcholine-induced modification of whole cell cardiac sodium current kinetics.

Shander GS, Undrovinas AI, Makielski JC.

J Mol Cell Cardiol. 1996 Apr;28(4):743-53.


The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium.

Remme CA, Verkerk AO, Hoogaars WM, Aanhaanen WT, Scicluna BP, Annink C, van den Hoff MJ, Wilde AA, van Veen TA, Veldkamp MW, de Bakker JM, Christoffels VM, Bezzina CR.

Basic Res Cardiol. 2009 Sep;104(5):511-22. doi: 10.1007/s00395-009-0012-8. Epub 2009 Mar 3.


[Effects of BmKIM on sodium current of isolated cardiomyocytes, transmembrane action potential and aconitine induced arrhythmia in vivo in rabbits].

Wang T, Huang CX, Jiang H, Tang QZ, Yang B, Li GS.

Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Feb;37(2):102-7. Chinese.


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