Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 312

1.

Flux Design: In silico design of cell factories based on correlation of pathway fluxes to desired properties.

Melzer G, Esfandabadi ME, Franco-Lara E, Wittmann C.

BMC Syst Biol. 2009 Dec 25;3:120. doi: 10.1186/1752-0509-3-120.

2.

From zero to hero--design-based systems metabolic engineering of Corynebacterium glutamicum for L-lysine production.

Becker J, Zelder O, Häfner S, Schröder H, Wittmann C.

Metab Eng. 2011 Mar;13(2):159-68. doi: 10.1016/j.ymben.2011.01.003. Epub 2011 Jan 15.

PMID:
21241816
3.

Systems-wide metabolic pathway engineering in Corynebacterium glutamicum for bio-based production of diaminopentane.

Kind S, Jeong WK, Schröder H, Wittmann C.

Metab Eng. 2010 Jul;12(4):341-51. doi: 10.1016/j.ymben.2010.03.005. Epub 2010 Apr 8.

PMID:
20381632
4.

Systems metabolic engineering of xylose-utilizing Corynebacterium glutamicum for production of 1,5-diaminopentane.

Buschke N, Becker J, Schäfer R, Kiefer P, Biedendieck R, Wittmann C.

Biotechnol J. 2013 May;8(5):557-70. doi: 10.1002/biot.201200367. Epub 2013 Apr 16.

PMID:
23447448
5.

Integration of in vivo and in silico metabolic fluxes for improvement of recombinant protein production.

Driouch H, Melzer G, Wittmann C.

Metab Eng. 2012 Jan;14(1):47-58. doi: 10.1016/j.ymben.2011.11.002. Epub 2011 Nov 20.

PMID:
22115737
6.

Systems metabolic engineering: the creation of microbial cell factories by rational metabolic design and evolution.

Furusawa C, Horinouchi T, Hirasawa T, Shimizu H.

Adv Biochem Eng Biotechnol. 2013;131:1-23. doi: 10.1007/10_2012_137. Review.

PMID:
22736112
7.

Metabolic fluxes and beyond-systems biology understanding and engineering of microbial metabolism.

Kohlstedt M, Becker J, Wittmann C.

Appl Microbiol Biotechnol. 2010 Nov;88(5):1065-75. doi: 10.1007/s00253-010-2854-2. Epub 2010 Sep 7. Review.

PMID:
20821203
8.

Systems metabolic engineering of Corynebacterium glutamicum for the production of the carbon-5 platform chemicals 5-aminovalerate and glutarate.

Rohles CM, Gießelmann G, Kohlstedt M, Wittmann C, Becker J.

Microb Cell Fact. 2016 Sep 13;15(1):154. doi: 10.1186/s12934-016-0553-0.

9.

Comparison between elementary flux modes analysis and 13C-metabolic fluxes measured in bacterial and plant cells.

Beurton-Aimar M, Beauvoit B, Monier A, Vallée F, Dieuaide-Noubhani M, Colombié S.

BMC Syst Biol. 2011 Jun 20;5:95. doi: 10.1186/1752-0509-5-95.

10.

Identification and elimination of the competing N-acetyldiaminopentane pathway for improved production of diaminopentane by Corynebacterium glutamicum.

Kind S, Jeong WK, Schröder H, Zelder O, Wittmann C.

Appl Environ Microbiol. 2010 Aug;76(15):5175-80. doi: 10.1128/AEM.00834-10. Epub 2010 Jun 18.

11.

In silico genome-scale reconstruction and validation of the Corynebacterium glutamicum metabolic network.

Kjeldsen KR, Nielsen J.

Biotechnol Bioeng. 2009 Feb 1;102(2):583-97. doi: 10.1002/bit.22067.

PMID:
18985611
12.

A giant market and a powerful metabolism: L-lysine provided by Corynebacterium glutamicum.

Eggeling L, Bott M.

Appl Microbiol Biotechnol. 2015 Apr;99(8):3387-94. doi: 10.1007/s00253-015-6508-2. Epub 2015 Mar 13. Review.

PMID:
25761623
13.

Flux variability scanning based on enforced objective flux for identifying gene amplification targets.

Park JM, Park HM, Kim WJ, Kim HU, Kim TY, Lee SY.

BMC Syst Biol. 2012 Aug 21;6:106. doi: 10.1186/1752-0509-6-106.

14.

In silico identification of gene amplification targets for improvement of lycopene production.

Choi HS, Lee SY, Kim TY, Woo HM.

Appl Environ Microbiol. 2010 May;76(10):3097-105. doi: 10.1128/AEM.00115-10. Epub 2010 Mar 26.

15.
16.

Metabolic fluxes in Corynebacterium glutamicum during lysine production with sucrose as carbon source.

Wittmann C, Kiefer P, Zelder O.

Appl Environ Microbiol. 2004 Dec;70(12):7277-87.

17.

Strain improvement by metabolic engineering: lysine production as a case study for systems biology.

Koffas M, Stephanopoulos G.

Curr Opin Biotechnol. 2005 Jun;16(3):361-6. Review.

PMID:
15961038
19.

Metabolic engineering of Escherichia coli and Corynebacterium glutamicum for biotechnological production of organic acids and amino acids.

Wendisch VF, Bott M, Eikmanns BJ.

Curr Opin Microbiol. 2006 Jun;9(3):268-74. Epub 2006 Apr 17. Review.

PMID:
16617034
20.

Computing the shortest elementary flux modes in genome-scale metabolic networks.

de Figueiredo LF, Podhorski A, Rubio A, Kaleta C, Beasley JE, Schuster S, Planes FJ.

Bioinformatics. 2009 Dec 1;25(23):3158-65. doi: 10.1093/bioinformatics/btp564. Epub 2009 Sep 30.

PMID:
19793869

Supplemental Content

Support Center