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Items: 1 to 20 of 99

2.

Quantitative dissection of the Notch:CSL interaction: insights into the Notch-mediated transcriptional switch.

Lubman OY, Ilagan MX, Kopan R, Barrick D.

J Mol Biol. 2007 Jan 19;365(3):577-89.

3.

Epstein-Barr virus nuclear protein 3C binds to the N-terminal (NTD) and beta trefoil domains (BTD) of RBP/CSL; only the NTD interaction is essential for lymphoblastoid cell growth.

Calderwood MA, Lee S, Holthaus AM, Blacklow SC, Kieff E, Johannsen E.

Virology. 2011 May 25;414(1):19-25. doi: 10.1016/j.virol.2011.02.018.

4.

Dissecting and circumventing the requirement for RAM in CSL-dependent Notch signaling.

Johnson SE, Barrick D.

PLoS One. 2012;7(8):e39093. doi: 10.1371/journal.pone.0039093.

5.

Epstein-Barr Virus Nuclear Antigen 3 (EBNA3) Proteins Regulate EBNA2 Binding to Distinct RBPJ Genomic Sites.

Wang A, Welch R, Zhao B, Ta T, Keleş S, Johannsen E.

J Virol. 2015 Dec 30;90(6):2906-19. doi: 10.1128/JVI.02737-15.

6.

Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 (vIRF4/K10) is a novel interaction partner of CSL/CBF1, the major downstream effector of Notch signaling.

Heinzelmann K, Scholz BA, Nowak A, Fossum E, Kremmer E, Haas J, Frank R, Kempkes B.

J Virol. 2010 Dec;84(23):12255-64. doi: 10.1128/JVI.01484-10.

7.

Counteracting effects of cellular Notch and Epstein-Barr virus EBNA2: implications for stromal effects on virus-host interactions.

Rowe M, Raithatha S, Shannon-Lowe C.

J Virol. 2014 Oct;88(20):12065-76. doi: 10.1128/JVI.01431-14.

8.

RAM-induced allostery facilitates assembly of a notch pathway active transcription complex.

Friedmann DR, Wilson JJ, Kovall RA.

J Biol Chem. 2008 May 23;283(21):14781-91. doi: 10.1074/jbc.M709501200.

9.

Transcriptional repression in the Notch pathway: thermodynamic characterization of CSL-MINT (Msx2-interacting nuclear target protein) complexes.

VanderWielen BD, Yuan Z, Friedmann DR, Kovall RA.

J Biol Chem. 2011 Apr 29;286(17):14892-902. doi: 10.1074/jbc.M110.181156.

10.

Thermodynamic binding analysis of Notch transcription complexes from Drosophila melanogaster.

Contreras AN, Yuan Z, Kovall RA.

Protein Sci. 2015 May;24(5):812-22. doi: 10.1002/pro.2652.

11.

The NP9 protein encoded by the human endogenous retrovirus HERV-K(HML-2) negatively regulates gene activation of the Epstein-Barr virus nuclear antigen 2 (EBNA2).

Gross H, Barth S, Pfuhl T, Willnecker V, Spurk A, Gurtsevitch V, Sauter M, Hu B, Noessner E, Mueller-Lantzsch N, Kremmer E, Grässer FA.

Int J Cancer. 2011 Sep 1;129(5):1105-15. doi: 10.1002/ijc.25760.

12.

EBNA2 and Notch signalling in Epstein-Barr virus mediated immortalization of B lymphocytes.

Zimber-Strobl U, Strobl LJ.

Semin Cancer Biol. 2001 Dec;11(6):423-34. Review.

PMID:
11669604
13.

Epstein-Barr virus nuclear antigen 2 trans-activates the cellular antiapoptotic bfl-1 gene by a CBF1/RBPJ kappa-dependent pathway.

Pegman PM, Smith SM, D'Souza BN, Loughran ST, Maier S, Kempkes B, Cahill PA, Simmons MJ, Gélinas C, Walls D.

J Virol. 2006 Aug;80(16):8133-44.

14.

Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA.

Kovall RA, Hendrickson WA.

EMBO J. 2004 Sep 1;23(17):3441-51.

15.

Effects of Linker Length and Transient Secondary Structure Elements in the Intrinsically Disordered Notch RAM Region on Notch Signaling.

Sherry KP, Johnson SE, Hatem CL, Majumdar A, Barrick D.

J Mol Biol. 2015 Nov 6;427(22):3587-97. doi: 10.1016/j.jmb.2015.09.001.

PMID:
26344835
16.

The effects of conformational heterogeneity on the binding of the Notch intracellular domain to effector proteins: a case of biologically tuned disorder.

Bertagna A, Toptygin D, Brand L, Barrick D.

Biochem Soc Trans. 2008 Apr;36(Pt 2):157-66. doi: 10.1042/BST0360157. Review.

PMID:
18363556
17.

Both Epstein-Barr viral nuclear antigen 2 (EBNA2) and activated Notch1 transactivate genes by interacting with the cellular protein RBP-J kappa.

Strobl LJ, Höfelmayr H, Stein C, Marschall G, Brielmeier M, Laux G, Bornkamm GW, Zimber-Strobl U.

Immunobiology. 1997 Dec;198(1-3):299-306. Review.

PMID:
9442401
18.

Kaposi's Sarcoma-associated herpesvirus lytic switch protein stimulates DNA binding of RBP-Jk/CSL to activate the Notch pathway.

Carroll KD, Bu W, Palmeri D, Spadavecchia S, Lynch SJ, Marras SA, Tyagi S, Lukac DM.

J Virol. 2006 Oct;80(19):9697-709.

19.

Structure and function of the CSL-KyoT2 corepressor complex: a negative regulator of Notch signaling.

Collins KJ, Yuan Z, Kovall RA.

Structure. 2014 Jan 7;22(1):70-81. doi: 10.1016/j.str.2013.10.010.

20.

EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding.

Portal D, Zhao B, Calderwood MA, Sommermann T, Johannsen E, Kieff E.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7808-13. doi: 10.1073/pnas.1104991108.

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