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Items: 1 to 20 of 97

1.

Toxicology and risk assessment of coumarin: focus on human data.

Abraham K, Wöhrlin F, Lindtner O, Heinemeyer G, Lampen A.

Mol Nutr Food Res. 2010 Feb;54(2):228-39. doi: 10.1002/mnfr.200900281. Review.

PMID:
20024932
2.

Risk assessment of coumarin using the bench mark dose (BMD) approach: children in Norway which regularly eat oatmeal porridge with cinnamon may exceed the TDI for coumarin with several folds.

Fotland TØ, Paulsen JE, Sanner T, Alexander J, Husøy T.

Food Chem Toxicol. 2012 Mar;50(3-4):903-12. doi: 10.1016/j.fct.2011.12.005. Epub 2011 Dec 9.

PMID:
22178604
3.

Quantification of flavoring constituents in cinnamon: high variation of coumarin in cassia bark from the German retail market and in authentic samples from indonesia.

Woehrlin F, Fry H, Abraham K, Preiss-Weigert A.

J Agric Food Chem. 2010 Oct 13;58(19):10568-75. doi: 10.1021/jf102112p.

PMID:
20853872
4.

The Relation between Hepatotoxicity and the Total Coumarin Intake from Traditional Japanese Medicines Containing Cinnamon Bark.

Iwata N, Kainuma M, Kobayashi D, Kubota T, Sugawara N, Uchida A, Ozono S, Yamamuro Y, Furusyo N, Ueda K, Tahara E, Shimazoe T.

Front Pharmacol. 2016 Jun 20;7:174. doi: 10.3389/fphar.2016.00174. eCollection 2016.

5.

Species differences in the metabolism and hepatotoxicity of coumarin.

Fentem JH, Fry JR.

Comp Biochem Physiol C. 1993 Jan;104(1):1-8. Review.

PMID:
8097443
6.

Relative bioavailability of coumarin from cinnamon and cinnamon-containing foods compared to isolated coumarin: a four-way crossover study in human volunteers.

Abraham K, Pfister M, Wöhrlin F, Lampen A.

Mol Nutr Food Res. 2011 Apr;55(4):644-53. doi: 10.1002/mnfr.201000394. Epub 2010 Dec 20.

PMID:
21462332
7.

Coumarin metabolism, toxicity and carcinogenicity: relevance for human risk assessment.

Lake BG.

Food Chem Toxicol. 1999 Apr;37(4):423-53. Review.

PMID:
10418958
8.

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials..

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. doi: 10.1016/j.fct.2008.02.008. Epub 2008 Feb 13. Review.

PMID:
18328408
9.

Species-specific differences in coumarin-induced hepatotoxicity as an example toxicogenomics-based approach to assessing risk of toxicity to humans.

Uehara T, Kiyosawa N, Shimizu T, Omura K, Hirode M, Imazawa T, Mizukawa Y, Ono A, Miyagishima T, Nagao T, Urushidani T.

Hum Exp Toxicol. 2008 Jan;27(1):23-35. doi: 10.1177/0960327107087910.

PMID:
18480146
10.

A safety assessment of coumarin taking into account species-specificity of toxicokinetics.

Felter SP, Vassallo JD, Carlton BD, Daston GP.

Food Chem Toxicol. 2006 Apr;44(4):462-75. Epub 2005 Oct 3. Review.

PMID:
16203076
11.

NTP Toxicology and Carcinogenesis Studies of Coumarin (CAS No. 91-64-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies).

National Toxicology Program ..

Natl Toxicol Program Tech Rep Ser. 1993 Sep;422:1-340.

12.

In silico methods for physiologically based biokinetic models describing bioactivation and detoxification of coumarin and estragole: implications for risk assessment.

Rietjens IM, Punt A, Schilter B, Scholz G, Delatour T, van Bladeren PJ.

Mol Nutr Food Res. 2010 Feb;54(2):195-207. doi: 10.1002/mnfr.200900211. Review.

PMID:
19943261
13.

Metabolic detoxification determines species differences in coumarin-induced hepatotoxicity.

Vassallo JD, Hicks SM, Daston GP, Lehman-McKeeman LD.

Toxicol Sci. 2004 Aug;80(2):249-57. Epub 2004 May 12.

PMID:
15141102
14.
15.

Coumarin-induced hepatotoxicity.

Loprinzi CL, Sloan J, Kugler J.

J Clin Oncol. 1997 Sep;15(9):3167-8. No abstract available.

PMID:
9294482
16.
17.

The FEMA GRAS assessment of trans-anethole used as a flavouring substance. Flavour and Extract Manufacturer's Association.

Newberne P, Smith RL, Doull J, Goodman JI, Munro IC, Portoghese PS, Wagner BM, Weil CS, Woods LA, Adams TB, Lucas CD, Ford RA.

Food Chem Toxicol. 1999 Jul;37(7):789-811.

PMID:
10496381
18.

Lympidem (a coumarin derivative) induced reversible hepatotoxicity in an adult Sri Lankan.

Satarasinghe RL, Jayawardana MA.

Drug Metabol Drug Interact. 2009;24(1):89-94.

PMID:
19354003
19.

Pharmacogenomics: its role in re-establishing coumarin as treatment for lymphedema.

Farinola N, Piller N.

Lymphat Res Biol. 2005 Summer;3(2):81-6. Review.

PMID:
16000056
20.

Coumarin toxicity in different strains of mice.

Endell W, Seidel G.

Agents Actions. 1978 Apr;8(3):299-302.

PMID:
665441

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