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Items: 1 to 20 of 150

1.

Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variability.

Ho RH, Leake BF, Kilkenny DM, Meyer Zu Schwabedissen HE, Glaeser H, Kroetz DL, Kim RB.

Pharmacogenet Genomics. 2010 Jan;20(1):45-57. doi: 10.1097/FPC.0b013e3283349eb0.

2.

Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing.

Byrne JA, Strautnieks SS, Ihrke G, Pagani F, Knisely AS, Linton KJ, Mieli-Vergani G, Thompson RJ.

Hepatology. 2009 Feb;49(2):553-67. doi: 10.1002/hep.22683.

PMID:
19101985
3.

A novel mutation within a transmembrane helix of the bile salt export pump (BSEP, ABCB11) with delayed development of cirrhosis.

Stindt J, Ellinger P, Weissenberger K, Dröge C, Herebian D, Mayatepek E, Homey B, Braun S, Schulte am Esch J, Horacek M, Canbay A, Schmitt L, Häussinger D, Kubitz R.

Liver Int. 2013 Nov;33(10):1527-35. doi: 10.1111/liv.12217. Epub 2013 Jun 12.

PMID:
23758865
4.

Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury.

Lang C, Meier Y, Stieger B, Beuers U, Lang T, Kerb R, Kullak-Ublick GA, Meier PJ, Pauli-Magnus C.

Pharmacogenet Genomics. 2007 Jan;17(1):47-60.

PMID:
17264802
5.

Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis.

Noe J, Kullak-Ublick GA, Jochum W, Stieger B, Kerb R, Haberl M, Müllhaupt B, Meier PJ, Pauli-Magnus C.

J Hepatol. 2005 Sep;43(3):536-43.

PMID:
16039748
6.

Short- and medium-chain fatty acids enhance the cell surface expression and transport capacity of the bile salt export pump (BSEP/ABCB11).

Kato T, Hayashi H, Sugiyama Y.

Biochim Biophys Acta. 2010 Sep;1801(9):1005-12. doi: 10.1016/j.bbalip.2010.04.002. Epub 2010 Apr 14.

PMID:
20398791
7.

Functional expression of the canalicular bile salt export pump of human liver.

Noé J, Stieger B, Meier PJ.

Gastroenterology. 2002 Nov;123(5):1659-66.

PMID:
12404240
8.

Genetic variability, haplotype structures, and ethnic diversity of hepatic transporters MDR3 (ABCB4) and bile salt export pump (ABCB11).

Lang T, Haberl M, Jung D, Drescher A, Schlagenhaufer R, Keil A, Mornhinweg E, Stieger B, Kullak-Ublick GA, Kerb R.

Drug Metab Dispos. 2006 Sep;34(9):1582-99. Epub 2006 Jun 8.

9.

Two N-linked glycans are required to maintain the transport activity of the bile salt export pump (ABCB11) in MDCK II cells.

Mochizuki K, Kagawa T, Numari A, Harris MJ, Itoh J, Watanabe N, Mine T, Arias IM.

Am J Physiol Gastrointest Liver Physiol. 2007 Mar;292(3):G818-28. Epub 2006 Nov 2.

10.

Interindividual variability of canalicular ATP-binding-cassette (ABC)-transporter expression in human liver.

Meier Y, Pauli-Magnus C, Zanger UM, Klein K, Schaeffeler E, Nussler AK, Nussler N, Eichelbaum M, Meier PJ, Stieger B.

Hepatology. 2006 Jul;44(1):62-74.

PMID:
16799996
11.

Recent advances in the exploration of the bile salt export pump (BSEP/ABCB11) function.

Telbisz Á, Homolya L.

Expert Opin Ther Targets. 2016;20(4):501-14. doi: 10.1517/14728222.2016.1102889. Epub 2015 Nov 17. Review.

PMID:
26573700
12.

Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver.

Stieger B, Fattinger K, Madon J, Kullak-Ublick GA, Meier PJ.

Gastroenterology. 2000 Feb;118(2):422-30.

PMID:
10648470
13.

Bile salt export pump (BSEP/ABCB11): trafficking and sorting disturbances.

Hayashi H, Sugiyama Y.

Curr Mol Pharmacol. 2013 Jul;6(2):95-103. Review.

PMID:
23876151
14.

Bile salt excretion in skate liver is mediated by a functional analog of Bsep/Spgp, the bile salt export pump.

Ballatori N, Rebbeor JF, Connolly GC, Seward DJ, Lenth BE, Henson JH, Sundaram P, Boyer JL.

Am J Physiol Gastrointest Liver Physiol. 2000 Jan;278(1):G57-63.

15.

Bile salt excretory pump: biology and pathobiology.

Suchy FJ, Ananthanarayanan M.

J Pediatr Gastroenterol Nutr. 2006 Jul;43 Suppl 1:S10-6. Review.

PMID:
16819395
16.
17.

Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis.

Jansen PL, Strautnieks SS, Jacquemin E, Hadchouel M, Sokal EM, Hooiveld GJ, Koning JH, De Jager-Krikken A, Kuipers F, Stellaard F, Bijleveld CM, Gouw A, Van Goor H, Thompson RJ, Müller M.

Gastroenterology. 1999 Dec;117(6):1370-9.

PMID:
10579978
18.

Biosynthesis and trafficking of the bile salt export pump, BSEP: therapeutic implications of BSEP mutations.

Soroka CJ, Boyer JL.

Mol Aspects Med. 2014 Jun;37:3-14. doi: 10.1016/j.mam.2013.05.001. Epub 2013 May 15. Review.

19.

Role of chemical structures and the 1331T>C bile salt export pump polymorphism in idiosyncratic drug-induced liver injury.

Ulzurrun E, Stephens C, Crespo E, Ruiz-Cabello F, Ruiz-Nuñez J, Saenz-López P, Moreno-Herrera I, Robles-Díaz M, Hallal H, Moreno-Planas JM, Cabello MR, Lucena MI, Andrade RJ.

Liver Int. 2013 Oct;33(9):1378-85. doi: 10.1111/liv.12193. Epub 2013 May 23.

PMID:
23701583
20.

Metabolic preconditioning protects BSEP/ABCB11-/- mice against cholestatic liver injury.

Fuchs CD, Paumgartner G, Wahlström A, Schwabl P, Reiberger T, Leditznig N, Stojakovic T, Rohr-Udilova N, Chiba P, Marschall HU, Trauner M.

J Hepatol. 2017 Jan;66(1):95-101. doi: 10.1016/j.jhep.2016.08.017. Epub 2016 Sep 1.

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