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Items: 1 to 20 of 93

1.

The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.

Krentz AD, Murphy MW, Kim S, Cook MS, Capel B, Zhu R, Matin A, Sarver AL, Parker KL, Griswold MD, Looijenga LH, Bardwell VJ, Zarkower D.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22323-8. doi: 10.1073/pnas.0905431106.

2.

Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line.

Krentz AD, Murphy MW, Zhang T, Sarver AL, Jain S, Griswold MD, Bardwell VJ, Zarkower D.

Dev Biol. 2013 May 1;377(1):67-78. doi: 10.1016/j.ydbio.2013.02.014.

3.

Testicular teratomas: an intersection of pluripotency, differentiation and cancer biology.

Bustamante-Marín X, Garness JA, Capel B.

Int J Dev Biol. 2013;57(2-4):201-10. doi: 10.1387/ijdb.130136bc. Review.

4.

Germ cell pluripotency, premature differentiation and susceptibility to testicular teratomas in mice.

Heaney JD, Anderson EL, Michelson MV, Zechel JL, Conrad PA, Page DC, Nadeau JH.

Development. 2012 May;139(9):1577-86. doi: 10.1242/dev.076851.

5.
6.

mRNA expression analysis and the molecular basis of neonatal testis defects in Dmrt1 mutant mice.

Fahrioglu U, Murphy MW, Zarkower D, Bardwell VJ.

Sex Dev. 2007;1(1):42-58. doi: 10.1159/000096238.

7.

Transcription factor TFAP2C regulates major programs required for murine fetal germ cell maintenance and haploinsufficiency predisposes to teratomas in male mice.

Schemmer J, Araúzo-Bravo MJ, Haas N, Schäfer S, Weber SN, Becker A, Eckert D, Zimmer A, Nettersheim D, Schorle H.

PLoS One. 2013 Aug 13;8(8):e71113. doi: 10.1371/journal.pone.0071113. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/579ac618-0ed0-4451-a4fc-10bad989024b.

8.

Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background.

Cook MS, Munger SC, Nadeau JH, Capel B.

Development. 2011 Jan;138(1):23-32. doi: 10.1242/dev.057000.

9.

Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis.

Murphy MW, Sarver AL, Rice D, Hatzi K, Ye K, Melnick A, Heckert LL, Zarkower D, Bardwell VJ.

Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13360-5. doi: 10.1073/pnas.1006243107.

11.

The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells.

Matson CK, Murphy MW, Griswold MD, Yoshida S, Bardwell VJ, Zarkower D.

Dev Cell. 2010 Oct 19;19(4):612-24. doi: 10.1016/j.devcel.2010.09.010.

12.

Dysregulation of the mitosis-meiosis switch in testicular carcinoma in situ.

Jørgensen A, Nielsen JE, Almstrup K, Toft BG, Petersen BL, Rajpert-De Meyts E.

J Pathol. 2013 Mar;229(4):588-98. doi: 10.1002/path.4154.

PMID:
23303528
13.

The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis.

Zhang T, Murphy MW, Gearhart MD, Bardwell VJ, Zarkower D.

Development. 2014 Oct;141(19):3662-71. doi: 10.1242/dev.113936.

14.

Loss of Etv5 decreases proliferation and RET levels in neonatal mouse testicular germ cells and causes an abnormal first wave of spermatogenesis.

Tyagi G, Carnes K, Morrow C, Kostereva NV, Ekman GC, Meling DD, Hostetler C, Griswold M, Murphy KM, Hess RA, Hofmann MC, Cooke PS.

Biol Reprod. 2009 Aug;81(2):258-66. doi: 10.1095/biolreprod.108.075200.

15.

An oncofetal and developmental perspective on testicular germ cell cancer.

Rijlaarsdam MA, Looijenga LH.

Semin Cancer Biol. 2014 Dec;29:59-74. doi: 10.1016/j.semcancer.2014.07.003. Review.

PMID:
25066859
16.

Identification and characterization of germ cell genes expressed in the F9 testicular teratoma stem cell line.

Kwon JT, Jin S, Choi H, Kim J, Jeong J, Kim J, Kim Y, Cho BN, Cho C.

PLoS One. 2014 Aug 25;9(8):e103837. doi: 10.1371/journal.pone.0103837.

17.

Regulation of pluripotency in male germline stem cells by Dmrt1.

Takashima S, Hirose M, Ogonuki N, Ebisuya M, Inoue K, Kanatsu-Shinohara M, Tanaka T, Nishida E, Ogura A, Shinohara T.

Genes Dev. 2013 Sep 15;27(18):1949-58. doi: 10.1101/gad.220194.113.

18.

Endogenous Nodal signaling regulates germ cell potency during mammalian testis development.

Spiller CM, Feng CW, Jackson A, Gillis AJ, Rolland AD, Looijenga LH, Koopman P, Bowles J.

Development. 2012 Nov;139(22):4123-32. doi: 10.1242/dev.083006.

19.

Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production.

Kimura T, Suzuki A, Fujita Y, Yomogida K, Lomeli H, Asada N, Ikeuchi M, Nagy A, Mak TW, Nakano T.

Development. 2003 Apr;130(8):1691-700.

20.

Vitamin D metabolism and effects on pluripotency genes and cell differentiation in testicular germ cell tumors in vitro and in vivo.

Blomberg Jensen M, Jørgensen A, Nielsen JE, Steinmeyer A, Leffers H, Juul A, Rajpert-De Meyts E.

Neoplasia. 2012 Oct;14(10):952-63.

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