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Items: 1 to 20 of 268

1.

Interactions between TLR7 and TLR9 agonists and receptors regulate innate immune responses by astrocytes and microglia.

Butchi NB, Du M, Peterson KE.

Glia. 2010 Apr 15;58(6):650-64. doi: 10.1002/glia.20952.

2.

The early induction of suppressor of cytokine signaling 1 and the downregulation of toll-like receptors 7 and 9 induce tolerance in costimulated macrophages.

Lee HJ, Kim KC, Han JA, Choi SS, Jung YJ.

Mol Cells. 2015 Jan 31;38(1):26-32. doi: 10.14348/molcells.2015.2136. Epub 2014 Dec 15.

3.

IL-4 suppresses the responses to TLR7 and TLR9 stimulation and increases the permissiveness to retroviral infection of murine conventional dendritic cells.

Sriram U, Xu J, Chain RW, Varghese L, Chakhtoura M, Bennett HL, Zoltick PW, Gallucci S.

PLoS One. 2014 Jan 29;9(1):e87668. doi: 10.1371/journal.pone.0087668. eCollection 2014.

4.

Natural and synthetic TLR7 ligands inhibit CpG-A- and CpG-C-oligodeoxynucleotide-induced IFN-alpha production.

Berghöfer B, Haley G, Frommer T, Bein G, Hackstein H.

J Immunol. 2007 Apr 1;178(7):4072-9.

5.

Guanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cells.

Römmler F, Hammel M, Waldhuber A, Müller T, Jurk M, Uhlmann E, Wagner H, Vollmer J, Miethke T.

PLoS One. 2015 Feb 19;10(2):e0116703. doi: 10.1371/journal.pone.0116703. eCollection 2015.

6.

Bruton's tyrosine kinase regulates TLR9 but not TLR7 signaling in human plasmacytoid dendritic cells.

Wang J, Lau KY, Jung J, Ravindran P, Barrat FJ.

Eur J Immunol. 2014 Apr;44(4):1130-6. doi: 10.1002/eji.201344030. Epub 2014 Jan 20.

7.

Additive melanoma suppression with intralesional phospholipid-conjugated TLR7 agonists and systemic IL-2.

Hayashi T, Chan M, Norton JT, Wu CC, Yao S, Cottam HB, Tawatao RI, Corr M, Carson DA, Daniels GA.

Melanoma Res. 2011 Feb;21(1):66-75. doi: 10.1097/CMR.0b013e328340ce6c.

8.

TLR7 and TLR9 trigger distinct neuroinflammatory responses in the CNS.

Butchi NB, Woods T, Du M, Morgan TW, Peterson KE.

Am J Pathol. 2011 Aug;179(2):783-94. doi: 10.1016/j.ajpath.2011.04.011. Epub 2011 Jun 14.

9.

TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection.

Nazmi A, Mukherjee S, Kundu K, Dutta K, Mahadevan A, Shankar SK, Basu A.

Neurobiol Dis. 2014 Sep;69:235-47. doi: 10.1016/j.nbd.2014.05.036. Epub 2014 Jun 5.

PMID:
24909816
10.

A human microsatellite DNA-mimicking oligodeoxynucleotide with CCT repeats negatively regulates TLR7/9-mediated innate immune responses via selected TLR pathways.

Sun R, Sun L, Bao M, Zhang Y, Wang L, Wu X, Hu D, Liu Y, Yu Y, Wang L.

Clin Immunol. 2010 Mar;134(3):262-76. doi: 10.1016/j.clim.2009.11.009. Epub 2010 Jan 19.

PMID:
20034855
11.

TLR9 agonist, but not TLR7/8, functions as an adjuvant to diminish FI-RSV vaccine-enhanced disease, while either agonist used as therapy during primary RSV infection increases disease severity.

Johnson TR, Rao S, Seder RA, Chen M, Graham BS.

Vaccine. 2009 May 18;27(23):3045-52. doi: 10.1016/j.vaccine.2009.03.026. Epub 2009 Apr 3.

12.

Toll like receptor 9 antagonism modulates spinal cord neuronal function and survival: Direct versus astrocyte-mediated mechanisms.

Acioglu C, Mirabelli E, Baykal AT, Ni L, Ratnayake A, Heary RF, Elkabes S.

Brain Behav Immun. 2016 Aug;56:310-24. doi: 10.1016/j.bbi.2016.03.027. Epub 2016 Apr 1.

PMID:
27044334
13.

CpG oligodeoxynucleotides induce the expression of the antimicrobial peptide cathelicidin in glial cells.

Brandenburg LO, Jansen S, Albrecht LJ, Merres J, Gerber J, Pufe T, Tauber SC.

J Neuroimmunol. 2013 Feb 15;255(1-2):18-31. doi: 10.1016/j.jneuroim.2012.10.012. Epub 2012 Nov 8.

PMID:
23141747
14.

Comparison of human B cell activation by TLR7 and TLR9 agonists.

Hanten JA, Vasilakos JP, Riter CL, Neys L, Lipson KE, Alkan SS, Birmachu W.

BMC Immunol. 2008 Jul 24;9:39. doi: 10.1186/1471-2172-9-39.

15.

Negative regulation of TLR9-mediated IFN-alpha induction by a small-molecule, synthetic TLR7 ligand.

Marshall JD, Heeke DS, Gesner ML, Livingston B, Van Nest G.

J Leukoc Biol. 2007 Sep;82(3):497-508. Epub 2007 Jun 12.

PMID:
17565046
16.

Toll-like receptor 7 mediates early innate immune responses to malaria.

Baccarella A, Fontana MF, Chen EC, Kim CC.

Infect Immun. 2013 Dec;81(12):4431-42. doi: 10.1128/IAI.00923-13. Epub 2013 Sep 16.

17.

Microglia Induce Neurotoxic IL-17+ γδ T Cells Dependent on TLR2, TLR4, and TLR9 Activation.

Derkow K, Krüger C, Dembny P, Lehnardt S.

PLoS One. 2015 Aug 19;10(8):e0135898. doi: 10.1371/journal.pone.0135898. eCollection 2015.

18.

The dysfunctional innate immune response triggered by Toll-like receptor activation is restored by TLR7/TLR8 and TLR9 ligands in cutaneous lichen planus.

Domingues R, de Carvalho GC, da Silva Oliveira LM, Futata Taniguchi E, Zimbres JM, Aoki V, da Silva Duarte AJ, Sato MN.

Br J Dermatol. 2015 Jan;172(1):48-55. doi: 10.1111/bjd.13214. Epub 2014 Nov 20.

PMID:
24976336
19.

Effects of Toll-like receptor 7 and Toll-like receptor 9 signaling stimulators and inhibitors on chronic lymphocytic leukemia cells ex vivo and their interactions with cladribine.

Wolska A, Cebula-Obrzut B, Smolewski P, Robak T.

Leuk Lymphoma. 2013 Jun;54(6):1268-78. doi: 10.3109/10428194.2012.741233. Epub 2012 Nov 20.

PMID:
23078646
20.

Analysis of the neuroinflammatory response to TLR7 stimulation in the brain: comparison of multiple TLR7 and/or TLR8 agonists.

Butchi NB, Pourciau S, Du M, Morgan TW, Peterson KE.

J Immunol. 2008 Jun 1;180(11):7604-12.

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