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Items: 1 to 20 of 112

1.

Narrowing the boundaries of the genetic architecture of schizophrenia.

Wray NR, Visscher PM.

Schizophr Bull. 2010 Jan;36(1):14-23. doi: 10.1093/schbul/sbp137. Epub 2009 Dec 8. Review.

2.

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder.

International Schizophrenia Consortium, Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Sklar P.

Nature. 2009 Aug 6;460(7256):748-52. doi: 10.1038/nature08185. Epub 2009 Jul 1.

3.

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.

Lee SH, DeCandia TR, Ripke S, Yang J; Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ); International Schizophrenia Consortium (ISC); Molecular Genetics of Schizophrenia Collaboration (MGS), Sullivan PF, Goddard ME, Keller MC, Visscher PM, Wray NR.

Nat Genet. 2012 Feb 19;44(3):247-50. doi: 10.1038/ng.1108.

4.

Common alleles contribute to schizophrenia in CNV carriers.

Tansey KE, Rees E, Linden DE, Ripke S, Chambert KD, Moran JL, McCarroll SA, Holmans P, Kirov G, Walters J, Owen MJ, O'Donovan MC.

Mol Psychiatry. 2016 Aug;21(8):1085-9. doi: 10.1038/mp.2015.143. Epub 2015 Sep 22.

5.

Biological insights from 108 schizophrenia-associated genetic loci.

Schizophrenia Working Group of the Psychiatric Genomics Consortium.

Nature. 2014 Jul 24;511(7510):421-7. doi: 10.1038/nature13595. Epub 2014 Jul 22.

6.

Molecular validation of the schizophrenia spectrum.

Bigdeli TB, Bacanu SA, Webb BT, Walsh D, O'Neill FA, Fanous AH, Riley BP, Kendler KS.

Schizophr Bull. 2014 Jan;40(1):60-5. doi: 10.1093/schbul/sbt122. Epub 2013 Aug 22.

7.

Research review: Polygenic methods and their application to psychiatric traits.

Wray NR, Lee SH, Mehta D, Vinkhuyzen AA, Dudbridge F, Middeldorp CM.

J Child Psychol Psychiatry. 2014 Oct;55(10):1068-87. doi: 10.1111/jcpp.12295. Epub 2014 Aug 1. Review.

PMID:
25132410
8.

Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia.

Owen MJ, Craddock N, O'Donovan MC.

Arch Gen Psychiatry. 2010 Jul;67(7):667-73. doi: 10.1001/archgenpsychiatry.2010.69. Review. No abstract available.

PMID:
20603448
9.

Common variants in polygenic schizophrenia.

Glessner JT, Hakonarson H.

Genome Biol. 2009;10(9):236. doi: 10.1186/gb-2009-10-9-236. Epub 2009 Sep 29. Review.

10.

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis.

Loh PR, Bhatia G, Gusev A, Finucane HK, Bulik-Sullivan BK, Pollack SJ; Schizophrenia Working Group of Psychiatric Genomics Consortium, de Candia TR, Lee SH, Wray NR, Kendler KS, O'Donovan MC, Neale BM, Patterson N, Price AL.

Nat Genet. 2015 Dec;47(12):1385-92. doi: 10.1038/ng.3431. Epub 2015 Nov 2.

11.

Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses.

Visscher PM, Goddard ME, Derks EM, Wray NR.

Mol Psychiatry. 2012 May;17(5):474-85. doi: 10.1038/mp.2011.65. Epub 2011 Jun 14. Review.

PMID:
21670730
12.

Evaluating empirical bounds on complex disease genetic architecture.

Agarwala V, Flannick J, Sunyaev S; GoT2D Consortium, Altshuler D.

Nat Genet. 2013 Dec;45(12):1418-27. doi: 10.1038/ng.2804. Epub 2013 Oct 20.

13.

Genetics of psychiatric disorders in the GWAS era: an update on schizophrenia.

Schwab SG, Wildenauer DB.

Eur Arch Psychiatry Clin Neurosci. 2013 Nov;263 Suppl 2:S147-54. doi: 10.1007/s00406-013-0450-z. Epub 2013 Sep 27. Review.

PMID:
24071914
14.

Puzzling over schizophrenia: schizophrenia as a pathway disease.

Sullivan PF.

Nat Med. 2012 Feb 6;18(2):210-1. doi: 10.1038/nm.2670. No abstract available.

15.

Genome-wide burden of deleterious coding variants increased in schizophrenia.

Loohuis LM, Vorstman JA, Ori AP, Staats KA, Wang T, Richards AL, Leonenko G, Walters JT, DeYoung J; GROUP Consortium, Cantor RM, Ophoff RA.

Nat Commun. 2015 Jul 9;6:7501. doi: 10.1038/ncomms8501.

16.

Synthetic associations in the context of genome-wide association scan signals.

Orozco G, Barrett JC, Zeggini E.

Hum Mol Genet. 2010 Oct 15;19(R2):R137-44. doi: 10.1093/hmg/ddq368. Epub 2010 Aug 30. Review.

17.

Large-scale genomics unveils the genetic architecture of psychiatric disorders.

Gratten J, Wray NR, Keller MC, Visscher PM.

Nat Neurosci. 2014 Jun;17(6):782-90. doi: 10.1038/nn.3708. Epub 2014 May 27. Review.

18.

Genetics: finding genes for schizophrenia.

Flint J, Munafò MR.

Curr Biol. 2014 Aug 18;24(16):R755-7. doi: 10.1016/j.cub.2014.07.018.

19.
20.

No evidence that common genetic risk variation is shared between schizophrenia and autism.

Vorstman JA, Anney RJ, Derks EM, Gallagher L, Gill M, de Jonge MV, van Engeland H, Kahn RS, Ophoff RA; Autism Genome Project, the International Schizophrenia Consortium.

Am J Med Genet B Neuropsychiatr Genet. 2013 Jan;162B(1):55-60. doi: 10.1002/ajmg.b.32121. Epub 2012 Nov 28.

PMID:
23193033

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