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Items: 1 to 20 of 125

1.

A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds.

Thanh GL, Abbenante G, Adamson G, Becker B, Clark C, Condie G, Falzun T, Grathwohl M, Gupta P, Hanson M, Huynh N, Katavic P, Kuipers K, Lam A, Liu L, Mann M, Mason J, McKeveney D, Muldoon C, Pearson A, Rajaratnam P, Ryan S, Tometzki G, Verquin G, Waanders J, West M, Wilcox N, Wimmer N, Yau A, Zuegg J, Meutermans W.

J Org Chem. 2010 Jan 1;75(1):197-203. doi: 10.1021/jo9021919.

PMID:
19961235
3.

Glycosamino acids: building blocks for combinatorial synthesis-implications for drug discovery.

Schweizer F.

Angew Chem Int Ed Engl. 2002 Jan 18;41(2):231-53. Review.

PMID:
12491402
4.

Molecular diversity through sugar scaffolds.

Le GT, Abbenante G, Becker B, Grathwohl M, Halliday J, Tometzki G, Zuegg J, Meutermans W.

Drug Discov Today. 2003 Aug 1;8(15):701-9. Review.

PMID:
12927513
5.
6.

Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold.

Abbenante G, Becker B, Blanc S, Clark C, Condie G, Fraser G, Grathwohl M, Halliday J, Henderson S, Lam A, Liu L, Mann M, Muldoon C, Pearson A, Premraj R, Ramsdale T, Rossetti T, Schafer K, Le Thanh G, Tometzki G, Vari F, Verquin G, Waanders J, West M, Wimmer N, Yau A, Zuegg J, Meutermans W.

J Med Chem. 2010 Aug 12;53(15):5576-86. doi: 10.1021/jm1002777.

PMID:
20684600
7.

Solid-phase synthetic route to multiple derivatives of a fundamental peptide unit.

Scott WL, Zhou Z, Zajdel P, Pawłowski M, O'Donnell MJ.

Molecules. 2010 Jul 20;15(7):4961-83. doi: 10.3390/molecules15074961.

8.

Molecular scaffold-based design and comparison of combinatorial libraries focused on the ATP-binding site of protein kinases.

Stahura FL, Xue L, Godden JW, Bajorath J.

J Mol Graph Model. 1999 Feb;17(1):1-9, 51-2.

PMID:
10660905
9.

Design of bioactive and structurally well-defined peptides from conformationally restricted libraries.

Pastor MT, Mora P, Ferrer-Montiel A, Pérez-Payá E.

Biopolymers. 2004;76(4):357-65.

PMID:
15386263
10.

Carbohydrates in peptide and protein design.

Jensen KJ, Brask J.

Biopolymers. 2005;80(6):747-61. Review.

PMID:
15929028
11.

Design, docking, and evaluation of multiple libraries against multiple targets.

Lamb ML, Burdick KW, Toba S, Young MM, Skillman AG, Zou X, Arnold JR, Kuntz ID.

Proteins. 2001 Feb 15;42(3):296-318.

PMID:
11151003
12.

General inverse solid-phase synthesis method for C-terminally modified peptide mimetics.

Sasubilli R, Gutheil WG.

J Comb Chem. 2004 Nov-Dec;6(6):911-5.

PMID:
15530118
13.

A versatile synthetic approach to peptidyl privileged structures using a "safety-catch" linker.

Horton DA, Severinsen R, Kofod-Hansen M, Bourne GT, Smythe ML.

J Comb Chem. 2005 May-Jun;7(3):421-35.

PMID:
15877471
14.

Assessing the scaffold diversity of screening libraries.

Krier M, Bret G, Rognan D.

J Chem Inf Model. 2006 Mar-Apr;46(2):512-24.

PMID:
16562979
15.
16.

Solid phase synthesis of biohybrid block copolymers.

Reynhout IC, Löwik DW, van Hest JC, Cornelissen JJ, Nolte RJ.

Chem Commun (Camb). 2005 Feb 7;(5):602-4. Epub 2004 Dec 8.

PMID:
15672149
17.

Combinatorial chemistry: libraries from libraries, the art of the diversity-oriented transformation of resin-bound peptides and chiral polyamides to low molecular weight acyclic and heterocyclic compounds.

Nefzi A, Ostresh JM, Yu Y, Houghten RA.

J Org Chem. 2004 May 28;69(11):3603-9. Erratum in: J Org Chem. 2004 Aug 6;69(16):5516. Yu, Jongping [corrected to Yu, Yongping].

PMID:
15152987
18.

"Libraries from libraries": chemical transformation of combinatorial libraries to extend the range and repertoire of chemical diversity.

Ostresh JM, Husar GM, Blondelle SE, Dörner B, Weber PA, Houghten RA.

Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):11138-42.

19.

A novel method to highly versatile monomeric PNA building blocks by multi component reactions.

Dömling A, Chi KZ, Barrère M.

Bioorg Med Chem Lett. 1999 Oct 4;9(19):2871-4.

PMID:
10522709
20.

Structural requirements for the biosynthesis of backbone cyclic peptide libraries.

Scott CP, Abel-Santos E, Jones AD, Benkovic SJ.

Chem Biol. 2001 Aug;8(8):801-15.

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