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Items: 1 to 20 of 172

1.

Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP.

Fogarty S, Hawley SA, Green KA, Saner N, Mustard KJ, Hardie DG.

Biochem J. 2010 Jan 27;426(1):109-18. doi: 10.1042/BJ20091372.

2.

Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase.

Hawley SA, Pan DA, Mustard KJ, Ross L, Bain J, Edelman AM, Frenguelli BG, Hardie DG.

Cell Metab. 2005 Jul;2(1):9-19.

3.

CaMKKβ is involved in AMP-activated protein kinase activation by baicalin in LKB1 deficient cell lines.

Ma Y, Yang F, Wang Y, Du Z, Liu D, Guo H, Shen J, Peng H.

PLoS One. 2012;7(10):e47900. doi: 10.1371/journal.pone.0047900. Epub 2012 Oct 22.

4.

AMPK is a direct adenylate charge-regulated protein kinase.

Oakhill JS, Steel R, Chen ZP, Scott JW, Ling N, Tam S, Kemp BE.

Science. 2011 Jun 17;332(6036):1433-5. doi: 10.1126/science.1200094.

5.

Thyroid hormone activates adenosine 5'-monophosphate-activated protein kinase via intracellular calcium mobilization and activation of calcium/calmodulin-dependent protein kinase kinase-beta.

Yamauchi M, Kambe F, Cao X, Lu X, Kozaki Y, Oiso Y, Seo H.

Mol Endocrinol. 2008 Apr;22(4):893-903. doi: 10.1210/me.2007-0249. Epub 2008 Jan 10.

6.

Ca2+/calmodulin-dependent protein kinase kinase is involved in AMP-activated protein kinase activation by alpha-lipoic acid in C2C12 myotubes.

Shen QW, Zhu MJ, Tong J, Ren J, Du M.

Am J Physiol Cell Physiol. 2007 Oct;293(4):C1395-403. Epub 2007 Aug 8.

PMID:
17687000
8.

Regulation of AMP-activated protein kinase by LKB1 and CaMKK in adipocytes.

Gormand A, Henriksson E, Ström K, Jensen TE, Sakamoto K, Göransson O.

J Cell Biochem. 2011 May;112(5):1364-75. doi: 10.1002/jcb.23053.

PMID:
21312243
9.

Differential AMP-activated Protein Kinase (AMPK) Recognition Mechanism of Ca2+/Calmodulin-dependent Protein Kinase Kinase Isoforms.

Fujiwara Y, Kawaguchi Y, Fujimoto T, Kanayama N, Magari M, Tokumitsu H.

J Biol Chem. 2016 Jun 24;291(26):13802-8. doi: 10.1074/jbc.M116.727867. Epub 2016 May 5.

10.

AMP-activated protein kinase in metabolic control and insulin signaling.

Towler MC, Hardie DG.

Circ Res. 2007 Feb 16;100(3):328-41. Review.

11.

The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases.

Hurley RL, Anderson KA, Franzone JM, Kemp BE, Means AR, Witters LA.

J Biol Chem. 2005 Aug 12;280(32):29060-6. Epub 2005 Jun 24.

12.

Characterization of the CaMKKβ-AMPK signaling complex.

Green MF, Anderson KA, Means AR.

Cell Signal. 2011 Dec;23(12):2005-12. doi: 10.1016/j.cellsig.2011.07.014. Epub 2011 Jul 23.

13.

Phosphorylation of AMPK by upstream kinases is required for activity in mammalian cells.

Willows R, Sanders MJ, Xiao B, Patel BR, Martin SR, Read J, Wilson JR, Hubbard J, Gamblin SJ, Carling D.

Biochem J. 2017 Aug 22;474(17):3059-3073. doi: 10.1042/BCJ20170458.

14.

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

Woods A, Dickerson K, Heath R, Hong SP, Momcilovic M, Johnstone SR, Carlson M, Carling D.

Cell Metab. 2005 Jul;2(1):21-33.

15.

Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade.

Sanders MJ, Grondin PO, Hegarty BD, Snowden MA, Carling D.

Biochem J. 2007 Apr 1;403(1):139-48.

16.

The calcium/CaMKKalpha/beta and the cAMP/PKA pathways are essential upstream regulators of AMPK activity in boar spermatozoa.

Hurtado de Llera A, Martin-Hidalgo D, Gil MC, Garcia-Marin LJ, Bragado MJ.

Biol Reprod. 2014 Feb 13;90(2):29. doi: 10.1095/biolreprod.113.112797. Print 2014 Feb.

PMID:
24389872
17.

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.

Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Mäkelä TP, Alessi DR, Hardie DG.

J Biol. 2003;2(4):28. doi: 10.1186/1475-4924-2-28. Epub 2003 Sep 24.

18.
19.

AMP-activated protein kinase-mediated feedback phosphorylation controls the Ca2+/calmodulin (CaM) dependence of Ca2+/CaM-dependent protein kinase kinase β.

Nakanishi A, Hatano N, Fujiwara Y, Sha'ri A, Takabatake S, Akano H, Kanayama N, Magari M, Nozaki N, Tokumitsu H.

J Biol Chem. 2017 Dec 1;292(48):19804-19813. doi: 10.1074/jbc.M117.805085. Epub 2017 Oct 3.

PMID:
28974582
20.

AMPK Causes Cell Cycle Arrest in LKB1-Deficient Cells via Activation of CAMKK2.

Fogarty S, Ross FA, Vara Ciruelos D, Gray A, Gowans GJ, Hardie DG.

Mol Cancer Res. 2016 Aug;14(8):683-95. doi: 10.1158/1541-7786.MCR-15-0479. Epub 2016 May 2.

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