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Items: 1 to 20 of 110

1.

TILRR, a novel IL-1RI co-receptor, potentiates MyD88 recruitment to control Ras-dependent amplification of NF-kappaB.

Zhang X, Shephard F, Kim HB, Palmer IR, McHarg S, Fowler GJ, O'Neill LA, Kiss-Toth E, Qwarnstrom EE.

J Biol Chem. 2010 Mar 5;285(10):7222-32. doi: 10.1074/jbc.M109.073429. Epub 2009 Nov 25. Erratum in: J Biol Chem. 2010 Jun 4;285(23):18122.

2.

Distinct control of MyD88 adapter-dependent and Akt kinase-regulated responses by the interleukin (IL)-1RI co-receptor, TILRR.

Zhang X, Pino GM, Shephard F, Kiss-Toth E, Qwarnstrom EE.

J Biol Chem. 2012 Apr 6;287(15):12348-52. doi: 10.1074/jbc.C111.321711. Epub 2012 Jan 19.

3.

Computational Modelling of NF-κB Activation by IL-1RI and Its Co-Receptor TILRR, Predicts a Role for Cytoskeletal Sequestration of IκBα in Inflammatory Signalling.

Rhodes DM, Smith SA, Holcombe M, Qwarnstrom EE.

PLoS One. 2015 Jun 25;10(6):e0129888. doi: 10.1371/journal.pone.0129888. eCollection 2015.

4.

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor.

Burns K, Clatworthy J, Martin L, Martinon F, Plumpton C, Maschera B, Lewis A, Ray K, Tschopp J, Volpe F.

Nat Cell Biol. 2000 Jun;2(6):346-51.

PMID:
10854325
5.

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.

Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, Brint E, Dunne A, Gray P, Harte MT, McMurray D, Smith DE, Sims JE, Bird TA, O'Neill LA.

Nature. 2001 Sep 6;413(6851):78-83.

PMID:
11544529
6.

MyD88, an adapter protein involved in interleukin-1 signaling.

Burns K, Martinon F, Esslinger C, Pahl H, Schneider P, Bodmer JL, Di Marco F, French L, Tschopp J.

J Biol Chem. 1998 May 15;273(20):12203-9.

7.

Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP.

Andreakos E, Sacre SM, Smith C, Lundberg A, Kiriakidis S, Stonehouse T, Monaco C, Feldmann M, Foxwell BM.

Blood. 2004 Mar 15;103(6):2229-37. Epub 2003 Nov 20.

8.

T1/ST2 signaling establishes it as a member of an expanding interleukin-1 receptor family.

Mitcham JL, Parnet P, Bonnert TP, Garka KE, Gerhart MJ, Slack JL, Gayle MA, Dower SK, Sims JE.

J Biol Chem. 1996 Mar 8;271(10):5777-83.

9.

The TLR2 ligand FSL-1 and the TLR5 ligand Flagellin mediate pro-inflammatory and pro-labour response via MyD88/TRAF6/NF-κB-dependent signalling.

Lim R, Barker G, Lappas M.

Am J Reprod Immunol. 2014 May;71(5):401-17. doi: 10.1111/aji.12229. Epub 2014 Mar 17.

PMID:
24635133
10.

Interactive sites in the MyD88 Toll/interleukin (IL) 1 receptor domain responsible for coupling to the IL1beta signaling pathway.

Li C, Zienkiewicz J, Hawiger J.

J Biol Chem. 2005 Jul 15;280(28):26152-9. Epub 2005 Apr 22.

12.

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling.

Muzio M, Ni J, Feng P, Dixit VM.

Science. 1997 Nov 28;278(5343):1612-5.

13.

Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes.

Li Q, Harraz MM, Zhou W, Zhang LN, Ding W, Zhang Y, Eggleston T, Yeaman C, Banfi B, Engelhardt JF.

Mol Cell Biol. 2006 Jan;26(1):140-54.

14.
15.

Peptide-mediated interference of TIR domain dimerization in MyD88 inhibits interleukin-1-dependent activation of NF-{kappa}B.

Loiarro M, Sette C, Gallo G, Ciacci A, Fantò N, Mastroianni D, Carminati P, Ruggiero V.

J Biol Chem. 2005 Apr 22;280(16):15809-14. Epub 2005 Mar 8.

17.

A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses.

Bartfai T, Behrens MM, Gaidarova S, Pemberton J, Shivanyuk A, Rebek J Jr.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7971-6. Epub 2003 Jun 10.

18.

WDR34 is a novel TAK1-associated suppressor of the IL-1R/TLR3/TLR4-induced NF-kappaB activation pathway.

Gao D, Wang R, Li B, Yang Y, Zhai Z, Chen DY.

Cell Mol Life Sci. 2009 Aug;66(15):2573-84. doi: 10.1007/s00018-009-0059-6. Epub 2009 Jun 12.

PMID:
19521662
19.

Cellular differentiation causes a selective down-regulation of interleukin (IL)-1beta-mediated NF-kappaB activation and IL-8 gene expression in intestinal epithelial cells.

Böcker U, Schottelius A, Watson JM, Holt L, Licato LL, Brenner DA, Sartor RB, Jobin C.

J Biol Chem. 2000 Apr 21;275(16):12207-13.

20.

MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics.

Davis CN, Mann E, Behrens MM, Gaidarova S, Rebek M, Rebek J Jr, Bartfai T.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2953-8. Epub 2006 Feb 13.

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