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IL-7 enhances thymic human T cell development in "human immune system" Rag2-/-IL-2Rgammac-/- mice without affecting peripheral T cell homeostasis.

van Lent AU, Dontje W, Nagasawa M, Siamari R, Bakker AQ, Pouw SM, Maijoor KA, Weijer K, Cornelissen JJ, Blom B, Di Santo JP, Spits H, Legrand N.

J Immunol. 2009 Dec 15;183(12):7645-55. doi: 10.4049/jimmunol.0902019.


Characterization in vitro and engraftment potential in vivo of human progenitor T cells generated from hematopoietic stem cells.

Awong G, Herer E, Surh CD, Dick JE, La Motte-Mohs RN, Zúñiga-Pflücker JC.

Blood. 2009 Jul 30;114(5):972-82. doi: 10.1182/blood-2008-10-187013. Epub 2009 Jun 2.


Homeostasis of naive and memory CD4+ T cells: IL-2 and IL-7 differentially regulate the balance between proliferation and Fas-mediated apoptosis.

Jaleco S, Swainson L, Dardalhon V, Burjanadze M, Kinet S, Taylor N.

J Immunol. 2003 Jul 1;171(1):61-8.


Stromal cell-derived factor 1/CXCR4 signaling is critical for early human T-cell development.

Hernández-López C, Varas A, Sacedón R, Jiménez E, Muñoz JJ, Zapata AG, Vicente A.

Blood. 2002 Jan 15;99(2):546-54.


The role of IL-7 in thymic and extrathymic development of TCR gamma delta cells.

Laky K, Lefrançois L, von Freeden-Jeffry U, Murray R, Puddington L.

J Immunol. 1998 Jul 15;161(2):707-13.


Inhibition of gamma delta T cell development and early thymocyte maturation in IL-7 -/- mice.

Moore TA, von Freeden-Jeffry U, Murray R, Zlotnik A.

J Immunol. 1996 Sep 15;157(6):2366-73.


Synergistic effect of IL-2, IL-12, and IL-18 on thymocyte apoptosis and Th1/Th2 cytokine expression.

Rodriguez-Galán MC, Bream JH, Farr A, Young HA.

J Immunol. 2005 Mar 1;174(5):2796-804.


Developmental and functional defects of thymic and epidermal V gamma 3 cells in IL-15-deficient and IFN regulatory factor-1-deficient mice.

De Creus A, Van Beneden K, Stevenaert F, Debacker V, Plum J, Leclercq G.

J Immunol. 2002 Jun 15;168(12):6486-93.


Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo.

Legrand N, Huntington ND, Nagasawa M, Bakker AQ, Schotte R, Strick-Marchand H, de Geus SJ, Pouw SM, Böhne M, Voordouw A, Weijer K, Di Santo JP, Spits H.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13224-9. doi: 10.1073/pnas.1101398108. Epub 2011 Jul 25.


Effects of IL-7 on early human thymocyte progenitor cells in vitro and in SCID-hu Thy/Liv mice.

Napolitano LA, Stoddart CA, Hanley MB, Wieder E, McCune JM.

J Immunol. 2003 Jul 15;171(2):645-54.


Distinct and overlapping patterns of cytokine regulation of thymic and bone marrow-derived NK cell development.

Cheng M, Charoudeh HN, Brodin P, Tang Y, Lakshmikanth T, Höglund P, Jacobsen SE, Sitnicka E.

J Immunol. 2009 Feb 1;182(3):1460-8.


Distinct requirements for IL-7 in development of TCR gamma delta cells during fetal and adult life.

Laky K, Lewis JM, Tigelaar RE, Puddington L.

J Immunol. 2003 Apr 15;170(8):4087-94.


Lineage divergence at the first TCR-dependent checkpoint: preferential γδ and impaired αβ T cell development in nonobese diabetic mice.

Feng N, Vegh P, Rothenberg EV, Yui MA.

J Immunol. 2011 Jan 15;186(2):826-37. doi: 10.4049/jimmunol.1002630. Epub 2010 Dec 10.


Critical roles of translationally controlled tumor protein in the homeostasis and TCR-mediated proliferation of peripheral T cells.

Wu PS, Yang CY, Yen JJ, Chou CH, Chen SH, Wang CK, Lai YG, Liao NS, Yang-Yen HF.

J Immunol. 2009 Aug 15;183(4):2373-81. doi: 10.4049/jimmunol.0900668. Epub 2009 Jul 15.


Morpholino antisense oligonucleotide-mediated gene knockdown during thymocyte development reveals role for Runx3 transcription factor in CD4 silencing during development of CD4-/CD8+ thymocytes.

Ehlers M, Laule-Kilian K, Petter M, Aldrian CJ, Grueter B, Würch A, Yoshida N, Watanabe T, Satake M, Steimle V.

J Immunol. 2003 Oct 1;171(7):3594-604.


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