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Dendritic cells activated by an anti-inflammatory agent induce CD4(+) T helper type 2 responses without impairing CD8(+) memory and effector cytotoxic T-lymphocyte responses.

Wang Y, Da'Dara AA, Thomas PG, Harn DA.

Immunology. 2010 Mar;129(3):406-17. doi: 10.1111/j.1365-2567.2009.03193.x. Epub 2009 Nov 16.


Ox40 costimulation enhances the development of T cell responses induced by dendritic cells in vivo.

De Smedt T, Smith J, Baum P, Fanslow W, Butz E, Maliszewski C.

J Immunol. 2002 Jan 15;168(2):661-70.


CD4+ Th-APC with acquired peptide/MHC class I and II complexes stimulate type 1 helper CD4+ and central memory CD8+ T cell responses.

Umeshappa CS, Huang H, Xie Y, Wei Y, Mulligan SJ, Deng Y, Xiang J.

J Immunol. 2009 Jan 1;182(1):193-206.


Active CD4+ helper T cells directly stimulate CD8+ cytotoxic T lymphocyte responses in wild-type and MHC II gene knockout C57BL/6 mice and transgenic RIP-mOVA mice expressing islet beta-cell ovalbumin antigen leading to diabetes.

Ye Z, Ahmed KA, Hao S, Zhang X, Xie Y, Munegowda MA, Meng Q, Chibbar R, Xiang J.

Autoimmunity. 2008 Nov;41(7):501-11. doi: 10.1080/08916930802069256.


A Neoglycoconjugate Containing the Human Milk Sugar LNFPIII Drives Anti-Inflammatory Activation of Antigen Presenting Cells in a CD14 Dependent Pathway.

Tundup S, Srivastava L, Norberg T, Watford W, Harn D.

PLoS One. 2015 Sep 4;10(9):e0137495. doi: 10.1371/journal.pone.0137495. eCollection 2015.


IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells.

Brown DM, Kamperschroer C, Dilzer AM, Roberts DM, Swain SL.

Cell Immunol. 2009;257(1-2):69-79. doi: 10.1016/j.cellimm.2009.03.002. Epub 2009 Mar 31.


Late dendritic cells are still able to evoke a potent alloreactive CTL response.

Repnik U, Bergant M, Wraber B, Jeras M.

Immunobiology. 2008;213(1):51-64. doi: 10.1016/j.imbio.2007.06.005. Epub 2007 Aug 6.


Memory CD8+ T cells protect dendritic cells from CTL killing.

Watchmaker PB, Urban JA, Berk E, Nakamura Y, Mailliard RB, Watkins SC, van Ham SM, Kalinski P.

J Immunol. 2008 Mar 15;180(6):3857-65.


CD4+ Th2 cells function alike effector Tr1 and Th1 cells through the deletion of a single cytokine IL-6 and IL-10 gene.

Ankathatti Munegowda M, Xu S, Freywald A, Xiang J.

Mol Immunol. 2012 Jun;51(2):143-9. doi: 10.1016/j.molimm.2012.02.120. Epub 2012 Mar 17.


Vitamin C treatment of mouse bone marrow-derived dendritic cells enhanced CD8(+) memory T cell production capacity of these cells in vivo.

Jeong YJ, Kim JH, Hong JM, Kang JS, Kim HR, Lee WJ, Hwang YI.

Immunobiology. 2014 Jul;219(7):554-64. doi: 10.1016/j.imbio.2014.03.006. Epub 2014 Mar 20.


Th1 and Th2 cells help CD8 T-cell responses.

Ekkens MJ, Shedlock DJ, Jung E, Troy A, Pearce EL, Shen H, Pearce EJ.

Infect Immun. 2007 May;75(5):2291-6. Epub 2007 Feb 26.


Administration of polysaccharides from Antrodia camphorata modulates dendritic cell function and alleviates allergen-induced T helper type 2 responses in a mouse model of asthma.

Liu KJ, Leu SJ, Su CH, Chiang BL, Chen YL, Lee YL.

Immunology. 2010 Mar;129(3):351-62. doi: 10.1111/j.1365-2567.2009.03175.x. Epub 2009 Nov 11.


Macrophage-derived dendritic cells have strong Th1-polarizing potential mediated by beta-chemokines rather than IL-12.

Zou W, Borvak J, Marches F, Wei S, Galanaud P, Emilie D, Curiel TJ.

J Immunol. 2000 Oct 15;165(8):4388-96.


Enhancement of effector CD8+ T-cell function by tumour-associated B7-H3 and modulation of its counter-receptor triggering receptor expressed on myeloid cell-like transcript 2 at tumour sites.

Kobori H, Hashiguchi M, Piao J, Kato M, Ritprajak P, Azuma M.

Immunology. 2010 Jul;130(3):363-73. doi: 10.1111/j.1365-2567.2009.03236.x. Epub 2010 Feb 5.


CD8 T cells inhibit IgE via dendritic cell IL-12 induction that promotes Th1 T cell counter-regulation.

Thomas MJ, Noble A, Sawicka E, Askenase PW, Kemeny DM.

J Immunol. 2002 Jan 1;168(1):216-23.


A helminth glycan induces APC maturation via alternative NF-kappa B activation independent of I kappa B alpha degradation.

Thomas PG, Carter MR, Da'dara AA, DeSimone TM, Harn DA.

J Immunol. 2005 Aug 15;175(4):2082-90.

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