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Items: 1 to 20 of 209

1.

Inhibition of procarcinogen-bioactivating human CYP1A1, CYP1A2 and CYP1B1 enzymes by melatonin.

Chang TK, Chen J, Yang G, Yeung EY.

J Pineal Res. 2010 Jan;48(1):55-64. doi: 10.1111/j.1600-079X.2009.00724.x. Epub 2009 Nov 16.

PMID:
19919601
2.
4.

Inhibition of aryl hydrocarbon receptor transactivation and DNA adduct formation by CYP1 isoform-selective metabolic deactivation of benzo[a]pyrene.

Endo K, Uno S, Seki T, Ariga T, Kusumi Y, Mitsumata M, Yamada S, Makishima M.

Toxicol Appl Pharmacol. 2008 Jul 15;230(2):135-43. doi: 10.1016/j.taap.2008.02.009. Epub 2008 Feb 21.

PMID:
18372000
6.
7.

Oxidation of xenobiotics by recombinant human cytochrome P450 1B1.

Shimada T, Gillam EM, Sutter TR, Strickland PT, Guengerich FP, Yamazaki H.

Drug Metab Dispos. 1997 May;25(5):617-22.

8.

Potent inhibition of carcinogen-bioactivating cytochrome P450 1B1 by the p53 inhibitor pifithrin alpha.

Sparfel L, Van Grevenynghe J, Le Vee M, Aninat C, Fardel O.

Carcinogenesis. 2006 Mar;27(3):656-63. Epub 2005 Oct 29.

PMID:
16258175
9.

Modulation of CYP1B1 and CYP1A1 gene expression and activation of aryl hydrocarbon receptor by Ginkgo biloba extract in MCF-10A human mammary epithelial cells.

Rajaraman G, Yang G, Chen J, Chang TK.

Can J Physiol Pharmacol. 2009 Sep;87(9):674-83. doi: 10.1139/y09-061.

PMID:
19794518
10.
11.

Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.

Uno S, Dragin N, Miller ML, Dalton TP, Gonzalez FJ, Nebert DW.

Free Radic Biol Med. 2008 Feb 15;44(4):570-83. Epub 2007 Nov 12.

12.
13.

For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential.

Dragin N, Dalton TP, Miller ML, Shertzer HG, Nebert DW.

J Biol Chem. 2006 Jul 7;281(27):18591-600. Epub 2006 Apr 24.

14.

Further assessment of 17alpha-ethinyl estradiol as an inhibitor of different human cytochrome P450 forms in vitro.

Chang SY, Chen C, Yang Z, Rodrigues AD.

Drug Metab Dispos. 2009 Aug;37(8):1667-75. doi: 10.1124/dmd.109.026997. Epub 2009 May 19.

15.

Arylhydrocarbon receptor-dependent induction of liver and lung cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in genetically engineered C57BL/6J mice.

Shimada T, Inoue K, Suzuki Y, Kawai T, Azuma E, Nakajima T, Shindo M, Kurose K, Sugie A, Yamagishi Y, Fujii-Kuriyama Y, Hashimoto M.

Carcinogenesis. 2002 Jul;23(7):1199-207.

PMID:
12117779
16.

Real-time polymerase chain reaction analysis of CYP1B1 gene expression in human liver.

Chang TK, Chen J, Pillay V, Ho JY, Bandiera SM.

Toxicol Sci. 2003 Jan;71(1):11-9.

PMID:
12520071
17.

Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism.

Androutsopoulos V, Arroo RR, Hall JF, Surichan S, Potter GA.

Breast Cancer Res. 2008;10(3):R39. doi: 10.1186/bcr2090. Epub 2008 May 2.

18.

Oral benzo[a]pyrene: understanding pharmacokinetics, detoxication, and consequences--Cyp1 knockout mouse lines as a paradigm.

Nebert DW, Shi Z, Gálvez-Peralta M, Uno S, Dragin N.

Mol Pharmacol. 2013 Sep;84(3):304-13. doi: 10.1124/mol.113.086637. Epub 2013 Jun 12. Review.

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