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Items: 1 to 20 of 110

1.

Solution structure of a covalently bound pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole hybrid to a 10mer DNA duplex.

Rettig M, Weingarth M, Langel W, Kamal A, Kumar PP, Weisz K.

Biochemistry. 2009 Dec 29;48(51):12223-32. doi: 10.1021/bi901655t.

PMID:
19911838
3.

Inter- and intrastrand DNA crosslinks by 2-fluoro-substituted pyrrolobenzodiazepine dimers: stability, stereochemistry and drug orientation.

Seifert J, Pezeshki S, Kamal A, Weisz K.

Org Biomol Chem. 2012 Sep 14;10(34):6850-60. doi: 10.1039/c2ob25654a. Epub 2012 Jul 26.

PMID:
22837138
5.

NMR structural studies on the covalent DNA binding of a pyrrolobenzodiazepine-naphthalimide conjugate.

Rettig M, Langel W, Kamal A, Weisz K.

Org Biomol Chem. 2010 Jul 21;8(14):3179-87. doi: 10.1039/c001893g. Epub 2010 May 20.

PMID:
20490406
7.
8.

Solution structure of a 2:1 C2-(2-naphthyl) pyrrolo[2,1-c][1,4]benzodiazepine DNA adduct: molecular basis for unexpectedly high DNA helix stabilization.

Antonow D, Barata T, Jenkins TC, Parkinson GN, Howard PW, Thurston DE, Zloh M.

Biochemistry. 2008 Nov 11;47(45):11818-29. doi: 10.1021/bi801225q. Epub 2008 Oct 17.

PMID:
18925745
9.

Nuclear magnetic resonance solution structures of inter- and intrastrand adducts of DNA cross-linker SJG-136.

Hopton SR, Thompson AS.

Biochemistry. 2011 May 31;50(21):4720-32. doi: 10.1021/bi102017e. Epub 2011 May 3.

PMID:
21488658
10.
12.

Solution structure of an O6-[4-oxo-4-(3-pyridyl)butyl]guanine adduct in an 11 mer DNA duplex: evidence for formation of a base triplex.

Peterson LA, Vu C, Hingerty BE, Broyde S, Cosman M.

Biochemistry. 2003 Nov 18;42(45):13134-44.

PMID:
14609323
13.
14.

Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction.

Feng B, Gorin A, Hingerty BE, Geacintov NE, Broyde S, Patel DJ.

Biochemistry. 1997 Nov 11;36(45):13769-79.

PMID:
9374853
15.
16.

Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex.

Mao B, Gu Z, Gorin A, Chen J, Hingerty BE, Amin S, Broyde S, Geacintov NE, Patel DJ.

Biochemistry. 1999 Aug 17;38(33):10831-42.

PMID:
10451380
17.

Pyrrolo[1,4]benzodiazepine antitumor antibiotics: evidence for two forms of tomaymycin bound to DNA.

Barkley MD, Cheatham S, Thurston DE, Hurley LH.

Biochemistry. 1986 May 20;25(10):3021-31.

PMID:
3718937
19.

Spectroscopic and calorimetric studies on the DNA recognition of pyrrolo[2,1-c][1,4]benzodiazepine hybrids.

Rettig M, Kamal A, Ramu R, Mikolajczak J, Weisz K.

Bioorg Med Chem. 2009 Jan 15;17(2):919-28. doi: 10.1016/j.bmc.2008.11.033. Epub 2008 Nov 19.

PMID:
19056283
20.

Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine.

Cosman M, de los Santos C, Fiala R, Hingerty BE, Ibanez V, Luna E, Harvey R, Geacintov NE, Broyde S, Patel DJ.

Biochemistry. 1993 Apr 27;32(16):4145-55.

PMID:
8476845

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