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Items: 1 to 20 of 87

1.

Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25.

Bierut LJ.

Trends Pharmacol Sci. 2010 Jan;31(1):46-51. doi: 10.1016/j.tips.2009.10.004. Epub 2009 Nov 5. Review.

2.

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.

Saccone NL, Wang JC, Breslau N, Johnson EO, Hatsukami D, Saccone SF, Grucza RA, Sun L, Duan W, Budde J, Culverhouse RC, Fox L, Hinrichs AL, Steinbach JH, Wu M, Rice JP, Goate AM, Bierut LJ.

Cancer Res. 2009 Sep 1;69(17):6848-56. doi: 10.1158/0008-5472.CAN-09-0786. Epub 2009 Aug 25.

3.

The polymorphism of the CHRNA5 gene and the strength of nicotine addiction in lung cancer and COPD patients.

Wojas-Krawczyk K, Krawczyk P, Biernacka B, Grzybek M, Kołodziej P, Kucharczyk T, Mlak R, Milanowski J.

Eur J Cancer Prev. 2012 Mar;21(2):111-7. doi: 10.1097/CEJ.0b013e32834c9b40.

PMID:
21955800
4.

Nicotine dependence and genetic variation in the nicotinic receptors.

Bierut LJ.

Drug Alcohol Depend. 2009 Oct 1;104 Suppl 1:S64-9. doi: 10.1016/j.drugalcdep.2009.06.003. Epub 2009 Jul 10. Review.

5.

Contribution of Variants in CHRNA5/A3/B4 Gene Cluster on Chromosome 15 to Tobacco Smoking: From Genetic Association to Mechanism.

Wen L, Jiang K, Yuan W, Cui W, Li MD.

Mol Neurobiol. 2016 Jan;53(1):472-484. doi: 10.1007/s12035-014-8997-x. Epub 2014 Dec 5. Review.

PMID:
25471942
6.

The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer.

Spitz MR, Amos CI, Dong Q, Lin J, Wu X.

J Natl Cancer Inst. 2008 Nov 5;100(21):1552-6. doi: 10.1093/jnci/djn363. Epub 2008 Oct 28.

7.

Intermediacy and gene-environment interaction: the example of CHRNA5-A3 region, smoking, nicotine dependence, and lung cancer.

Wacholder S, Chatterjee N, Caporaso N.

J Natl Cancer Inst. 2008 Nov 5;100(21):1488-91. doi: 10.1093/jnci/djn380. Epub 2008 Oct 28. No abstract available.

8.

Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence.

Chen X, Chen J, Williamson VS, An SS, Hettema JM, Aggen SH, Neale MC, Kendler KS.

Am J Med Genet B Neuropsychiatr Genet. 2009 Oct 5;150B(7):926-33. doi: 10.1002/ajmg.b.30919.

9.

Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5-A3 genetic locus and lung cancer risk.

Wang J, Spitz MR, Amos CI, Wilkinson AV, Wu X, Shete S.

Cancer. 2010 Jul 15;116(14):3458-62. doi: 10.1002/cncr.25085.

10.

Nicotine dependence may link the 15q25 locus to lung cancer risk.

Galvan A, Dragani TA.

Carcinogenesis. 2010 Mar;31(3):331-3. doi: 10.1093/carcin/bgp282. Epub 2009 Nov 12.

PMID:
19910382
11.

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

Saccone NL, Culverhouse RC, Schwantes-An TH, Cannon DS, Chen X, Cichon S, Giegling I, Han S, Han Y, Keskitalo-Vuokko K, Kong X, Landi MT, Ma JZ, Short SE, Stephens SH, Stevens VL, Sun L, Wang Y, Wenzlaff AS, Aggen SH, Breslau N, Broderick P, Chatterjee N, Chen J, Heath AC, Heliövaara M, Hoft NR, Hunter DJ, Jensen MK, Martin NG, Montgomery GW, Niu T, Payne TJ, Peltonen L, Pergadia ML, Rice JP, Sherva R, Spitz MR, Sun J, Wang JC, Weiss RB, Wheeler W, Witt SH, Yang BZ, Caporaso NE, Ehringer MA, Eisen T, Gapstur SM, Gelernter J, Houlston R, Kaprio J, Kendler KS, Kraft P, Leppert MF, Li MD, Madden PA, Nöthen MM, Pillai S, Rietschel M, Rujescu D, Schwartz A, Amos CI, Bierut LJ.

PLoS Genet. 2010 Aug 5;6(8). pii: e1001053. doi: 10.1371/journal.pgen.1001053.

12.

Variants in nicotinic receptors and risk for nicotine dependence.

Bierut LJ, Stitzel JA, Wang JC, Hinrichs AL, Grucza RA, Xuei X, Saccone NL, Saccone SF, Bertelsen S, Fox L, Horton WJ, Breslau N, Budde J, Cloninger CR, Dick DM, Foroud T, Hatsukami D, Hesselbrock V, Johnson EO, Kramer J, Kuperman S, Madden PA, Mayo K, Nurnberger J Jr, Pomerleau O, Porjesz B, Reyes O, Schuckit M, Swan G, Tischfield JA, Edenberg HJ, Rice JP, Goate AM.

Am J Psychiatry. 2008 Sep;165(9):1163-71. doi: 10.1176/appi.ajp.2008.07111711. Epub 2008 Jun 2.

13.

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease.

Thorgeirsson TE, Geller F, Sulem P, Rafnar T, Wiste A, Magnusson KP, Manolescu A, Thorleifsson G, Stefansson H, Ingason A, Stacey SN, Bergthorsson JT, Thorlacius S, Gudmundsson J, Jonsson T, Jakobsdottir M, Saemundsdottir J, Olafsdottir O, Gudmundsson LJ, Bjornsdottir G, Kristjansson K, Skuladottir H, Isaksson HJ, Gudbjartsson T, Jones GT, Mueller T, Gottsäter A, Flex A, Aben KK, de Vegt F, Mulders PF, Isla D, Vidal MJ, Asin L, Saez B, Murillo L, Blondal T, Kolbeinsson H, Stefansson JG, Hansdottir I, Runarsdottir V, Pola R, Lindblad B, van Rij AM, Dieplinger B, Haltmayer M, Mayordomo JI, Kiemeney LA, Matthiasson SE, Oskarsson H, Tyrfingsson T, Gudbjartsson DF, Gulcher JR, Jonsson S, Thorsteinsdottir U, Kong A, Stefansson K.

Nature. 2008 Apr 3;452(7187):638-42. doi: 10.1038/nature06846.

14.

The nicotinic acetylcholine receptor CHRNA5/A3/B4 gene cluster: dual role in nicotine addiction and lung cancer.

Improgo MR, Scofield MD, Tapper AR, Gardner PD.

Prog Neurobiol. 2010 Oct;92(2):212-26. doi: 10.1016/j.pneurobio.2010.05.003. Epub 2010 Jun 4. Review.

15.

Association between a 15q25 gene variant, nicotine-related habits, lung cancer and COPD among 56,307 individuals from the HUNT study in Norway.

Gabrielsen ME, Romundstad P, Langhammer A, Krokan HE, Skorpen F.

Eur J Hum Genet. 2013 Nov;21(11):1293-9. doi: 10.1038/ejhg.2013.26. Epub 2013 Feb 27.

16.

The CHRNA5-A3-B4 gene cluster in nicotine addiction.

Berrettini WH, Doyle GA.

Mol Psychiatry. 2012 Sep;17(9):856-66. doi: 10.1038/mp.2011.122. Epub 2011 Oct 4. Review.

PMID:
21968931
17.

Nicotinic acetylcholine receptor genes on chromosome 15q25.1 are associated with nicotine and opioid dependence severity.

Erlich PM, Hoffman SN, Rukstalis M, Han JJ, Chu X, Linda Kao WH, Gerhard GS, Stewart WF, Boscarino JA.

Hum Genet. 2010 Nov;128(5):491-9. doi: 10.1007/s00439-010-0876-6. Epub 2010 Aug 20.

PMID:
20725741
18.

Peer smoking and the nicotinic receptor genes: an examination of genetic and environmental risks for nicotine dependence.

Johnson EO, Chen LS, Breslau N, Hatsukami D, Robbins T, Saccone NL, Grucza RA, Bierut LJ.

Addiction. 2010 Nov;105(11):2014-22. doi: 10.1111/j.1360-0443.2010.03074.x. Epub 2010 Sep 15.

19.

Role of nicotine dependence on the relationship between variants in the nicotinic receptor genes and risk of lung adenocarcinoma.

Tseng TS, Park JY, Zabaleta J, Moody-Thomas S, Sothern MS, Chen T, Evans DE, Lin HY.

PLoS One. 2014 Sep 18;9(9):e107268. doi: 10.1371/journal.pone.0107268. eCollection 2014.

20.

Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans.

Olfson E, Saccone NL, Johnson EO, Chen LS, Culverhouse R, Doheny K, Foltz SM, Fox L, Gogarten SM, Hartz S, Hetrick K, Laurie CC, Marosy B, Amin N, Arnett D, Barr RG, Bartz TM, Bertelsen S, Borecki IB, Brown MR, Chasman DI, van Duijn CM, Feitosa MF, Fox ER, Franceschini N, Franco OH, Grove ML, Guo X, Hofman A, Kardia SL, Morrison AC, Musani SK, Psaty BM, Rao DC, Reiner AP, Rice K, Ridker PM, Rose LM, Schick UM, Schwander K, Uitterlinden AG, Vojinovic D, Wang JC, Ware EB, Wilson G, Yao J, Zhao W, Breslau N, Hatsukami D, Stitzel JA, Rice J, Goate A, Bierut LJ.

Mol Psychiatry. 2016 May;21(5):601-7. doi: 10.1038/mp.2015.105. Epub 2015 Aug 4.

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