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A neutralizing human monoclonal antibody protects against lethal disease in a new ferret model of acute nipah virus infection.

Bossart KN, Zhu Z, Middleton D, Klippel J, Crameri G, Bingham J, McEachern JA, Green D, Hancock TJ, Chan YP, Hickey AC, Dimitrov DS, Wang LF, Broder CC.

PLoS Pathog. 2009 Oct;5(10):e1000642. doi: 10.1371/journal.ppat.1000642. Epub 2009 Oct 30.


Therapeutic treatment of Nipah virus infection in nonhuman primates with a neutralizing human monoclonal antibody.

Geisbert TW, Mire CE, Geisbert JB, Chan YP, Agans KN, Feldmann F, Fenton KA, Zhu Z, Dimitrov DS, Scott DP, Bossart KN, Feldmann H, Broder CC.

Sci Transl Med. 2014 Jun 25;6(242):242ra82. doi: 10.1126/scitranslmed.3008929.


Vaccination of ferrets with a recombinant G glycoprotein subunit vaccine provides protection against Nipah virus disease for over 12 months.

Pallister JA, Klein R, Arkinstall R, Haining J, Long F, White JR, Payne J, Feng YR, Wang LF, Broder CC, Middleton D.

Virol J. 2013 Jul 16;10:237. doi: 10.1186/1743-422X-10-237.


Single-dose live-attenuated vesicular stomatitis virus-based vaccine protects African green monkeys from Nipah virus disease.

Prescott J, DeBuysscher BL, Feldmann F, Gardner DJ, Haddock E, Martellaro C, Scott D, Feldmann H.

Vaccine. 2015 Jun 4;33(24):2823-9. doi: 10.1016/j.vaccine.2015.03.089. Epub 2015 Apr 10.


Nipah virus: vaccination and passive protection studies in a hamster model.

Guillaume V, Contamin H, Loth P, Georges-Courbot MC, Lefeuvre A, Marianneau P, Chua KB, Lam SK, Buckland R, Deubel V, Wild TF.

J Virol. 2004 Jan;78(2):834-40.


Single injection recombinant vesicular stomatitis virus vaccines protect ferrets against lethal Nipah virus disease.

Mire CE, Versteeg KM, Cross RW, Agans KN, Fenton KA, Whitt MA, Geisbert TW.

Virol J. 2013 Dec 13;10:353. doi: 10.1186/1743-422X-10-353.


Immunization strategies against henipaviruses.

Broder CC, Geisbert TW, Xu K, Nikolov DB, Wang LF, Middleton D, Pallister J, Bossart KN.

Curr Top Microbiol Immunol. 2012;359:197-223. doi: 10.1007/82_2012_213. Review.


Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets.

Satterfield BA, Cross RW, Fenton KA, Borisevich V, Agans KN, Deer DJ, Graber J, Basler CF, Geisbert TW, Mire CE.

J Virol. 2016 Jun 24;90(14):6326-6343. doi: 10.1128/JVI.00215-16. Print 2016 Jul 15.


A recombinant Hendra virus G glycoprotein-based subunit vaccine protects ferrets from lethal Hendra virus challenge.

Pallister J, Middleton D, Wang LF, Klein R, Haining J, Robinson R, Yamada M, White J, Payne J, Feng YR, Chan YP, Broder CC.

Vaccine. 2011 Aug 5;29(34):5623-30. doi: 10.1016/j.vaccine.2011.06.015. Epub 2011 Jul 1.


Recombinant measles virus vaccine expressing the Nipah virus glycoprotein protects against lethal Nipah virus challenge.

Yoneda M, Georges-Courbot MC, Ikeda F, Ishii M, Nagata N, Jacquot F, Raoul H, Sato H, Kai C.

PLoS One. 2013;8(3):e58414. doi: 10.1371/journal.pone.0058414. Epub 2013 Mar 14.


Single-dose live-attenuated Nipah virus vaccines confer complete protection by eliciting antibodies directed against surface glycoproteins.

DeBuysscher BL, Scott D, Marzi A, Prescott J, Feldmann H.

Vaccine. 2014 May 7;32(22):2637-44. doi: 10.1016/j.vaccine.2014.02.087. Epub 2014 Mar 12.


A neutralizing human monoclonal antibody protects african green monkeys from hendra virus challenge.

Bossart KN, Geisbert TW, Feldmann H, Zhu Z, Feldmann F, Geisbert JB, Yan L, Feng YR, Brining D, Scott D, Wang Y, Dimitrov AS, Callison J, Chan YP, Hickey AC, Dimitrov DS, Broder CC, Rockx B.

Sci Transl Med. 2011 Oct 19;3(105):105ra103. doi: 10.1126/scitranslmed.3002901.


Henipavirus pathogenesis and antiviral approaches.

Mathieu C, Horvat B.

Expert Rev Anti Infect Ther. 2015 Mar;13(3):343-54. doi: 10.1586/14787210.2015.1001838. Epub 2015 Jan 29. Review.


Type I interferon signaling protects mice from lethal henipavirus infection.

Dhondt KP, Mathieu C, Chalons M, Reynaud JM, Vallve A, Raoul H, Horvat B.

J Infect Dis. 2013 Jan 1;207(1):142-51. doi: 10.1093/infdis/jis653. Epub 2012 Oct 22.


Acute Hendra virus infection: Analysis of the pathogenesis and passive antibody protection in the hamster model.

Guillaume V, Wong KT, Looi RY, Georges-Courbot MC, Barrot L, Buckland R, Wild TF, Horvat B.

Virology. 2009 May 10;387(2):459-65. doi: 10.1016/j.virol.2009.03.001. Epub 2009 Mar 28.


A treatment for and vaccine against the deadly Hendra and Nipah viruses.

Broder CC, Xu K, Nikolov DB, Zhu Z, Dimitrov DS, Middleton D, Pallister J, Geisbert TW, Bossart KN, Wang LF.

Antiviral Res. 2013 Oct;100(1):8-13. doi: 10.1016/j.antiviral.2013.06.012. Epub 2013 Jul 6. Review.


Chloroquine administration does not prevent Nipah virus infection and disease in ferrets.

Pallister J, Middleton D, Crameri G, Yamada M, Klein R, Hancock TJ, Foord A, Shiell B, Michalski W, Broder CC, Wang LF.

J Virol. 2009 Nov;83(22):11979-82. doi: 10.1128/JVI.01847-09. Epub 2009 Sep 16.


A Hendra virus G glycoprotein subunit vaccine protects African green monkeys from Nipah virus challenge.

Bossart KN, Rockx B, Feldmann F, Brining D, Scott D, LaCasse R, Geisbert JB, Feng YR, Chan YP, Hickey AC, Broder CC, Feldmann H, Geisbert TW.

Sci Transl Med. 2012 Aug 8;4(146):146ra107. doi: 10.1126/scitranslmed.3004241.


Development of an acute and highly pathogenic nonhuman primate model of Nipah virus infection.

Geisbert TW, Daddario-DiCaprio KM, Hickey AC, Smith MA, Chan YP, Wang LF, Mattapallil JJ, Geisbert JB, Bossart KN, Broder CC.

PLoS One. 2010 May 18;5(5):e10690. doi: 10.1371/journal.pone.0010690.


Exceptionally potent cross-reactive neutralization of Nipah and Hendra viruses by a human monoclonal antibody.

Zhu Z, Bossart KN, Bishop KA, Crameri G, Dimitrov AS, McEachern JA, Feng Y, Middleton D, Wang LF, Broder CC, Dimitrov DS.

J Infect Dis. 2008 Mar 15;197(6):846-53. doi: 10.1086/528801.


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