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Items: 1 to 20 of 93


Toll-like receptors and ischemic brain injury.

Gesuete R, Kohama SG, Stenzel-Poore MP.

J Neuropathol Exp Neurol. 2014 May;73(5):378-86. doi: 10.1097/NEN.0000000000000068. Review.


Toll-like receptor tolerance as a mechanism for neuroprotection.

Vartanian K, Stenzel-Poore M.

Transl Stroke Res. 2010 Dec 1;1(4):252-260.


Function and mechanism of toll-like receptors in cerebral ischemic tolerance: from preconditioning to treatment.

Wang PF, Xiong XY, Chen J, Wang YC, Duan W, Yang QW.

J Neuroinflammation. 2015 Apr 28;12:80. doi: 10.1186/s12974-015-0301-0. Review.


LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury.

Vartanian KB, Stevens SL, Marsh BJ, Williams-Karnesky R, Lessov NS, Stenzel-Poore MP.

J Neuroinflammation. 2011 Oct 14;8:140. doi: 10.1186/1742-2094-8-140.


Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance.

Karikó K, Weissman D, Welsh FA.

J Cereb Blood Flow Metab. 2004 Nov;24(11):1288-304. Review.


Toll-like receptors and tolerance to ischaemic injury in the brain.

Stevens SL, Stenzel-Poore MP.

Biochem Soc Trans. 2006 Dec;34(Pt 6):1352-5.


Toll-like receptor signaling in endogenous neuroprotection and stroke.

Marsh BJ, Williams-Karnesky RL, Stenzel-Poore MP.

Neuroscience. 2009 Feb 6;158(3):1007-20. doi: 10.1016/j.neuroscience.2008.07.067. Review.


Multiple preconditioning paradigms converge on interferon regulatory factor-dependent signaling to promote tolerance to ischemic brain injury.

Stevens SL, Leung PY, Vartanian KB, Gopalan B, Yang T, Simon RP, Stenzel-Poore MP.

J Neurosci. 2011 Jun 8;31(23):8456-63. doi: 10.1523/JNEUROSCI.0821-11.2011.


Toll-like receptor 7 preconditioning induces robust neuroprotection against stroke by a novel type I interferon-mediated mechanism.

Leung PY, Stevens SL, Packard AE, Lessov NS, Yang T, Conrad VK, van den Dungen NN, Simon RP, Stenzel-Poore MP.

Stroke. 2012 May;43(5):1383-9. doi: 10.1161/STROKEAHA.111.641522.


Ischemic preconditioning in the brain.

Davis DP, Patel PM.

Curr Opin Anaesthesiol. 2003 Oct;16(5):447-52.


Ischemic preconditioning alters the epigenetic profile of the brain from ischemic intolerance to ischemic tolerance.

Thompson JW, Dave KR, Young JI, Perez-Pinzon MA.

Neurotherapeutics. 2013 Oct;10(4):789-97. doi: 10.1007/s13311-013-0202-9. Review.


Steps to translate preconditioning from basic research to the clinic.

Bahjat FR, Gesuete R, Stenzel-Poore MP.

Transl Stroke Res. 2013 Feb;4(1):89-103. doi: 10.1007/s12975-012-0223-4. Review.


Preconditioning with recombinant high-mobility group box 1 induces ischemic tolerance in a rat model of focal cerebral ischemia-reperfusion.

Wang C, Liu XX, Huang KB, Yin SB, Wei JJ, Hu YF, Gu Y, Zheng GQ.

J Neurochem. 2016 May;137(4):576-88. doi: 10.1111/jnc.13611.


Toll-like receptors: novel pharmacological targets for the treatment of neurological diseases.

Marsh BJ, Stenzel-Poore MP.

Curr Opin Pharmacol. 2008 Feb;8(1):8-13. Review.


CpG preconditioning regulates miRNA expression that modulates genomic reprogramming associated with neuroprotection against ischemic injury.

Vartanian KB, Mitchell HD, Stevens SL, Conrad VK, McDermott JE, Stenzel-Poore MP.

J Cereb Blood Flow Metab. 2015 Feb;35(2):257-66. doi: 10.1038/jcbfm.2014.193.


Toll-like receptors in cerebral ischemic inflammatory injury.

Wang YC, Lin S, Yang QW.

J Neuroinflammation. 2011 Oct 8;8:134. doi: 10.1186/1742-2094-8-134. Review.


Systemic lipopolysaccharide protects the brain from ischemic injury by reprogramming the response of the brain to stroke: a critical role for IRF3.

Marsh B, Stevens SL, Packard AE, Gopalan B, Hunter B, Leung PY, Harrington CA, Stenzel-Poore MP.

J Neurosci. 2009 Aug 5;29(31):9839-49. doi: 10.1523/JNEUROSCI.2496-09.2009.


Post-conditioning and reperfusion injury in the treatment of stroke.

Simon R.

Dose Response. 2014 Jul 7;12(4):590-9. doi: 10.2203/dose-response.14-026.Simon.

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