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Items: 1 to 20 of 118

1.

The mAKAPbeta scaffold regulates cardiac myocyte hypertrophy via recruitment of activated calcineurin.

Li J, Negro A, Lopez J, Bauman AL, Henson E, Dodge-Kafka K, Kapiloff MS.

J Mol Cell Cardiol. 2010 Feb;48(2):387-94. doi: 10.1016/j.yjmcc.2009.10.023. Epub 2009 Oct 31.

2.

Muscle A-kinase-anchoring protein-β-bound calcineurin toggles active and repressive transcriptional complexes of myocyte enhancer factor 2D.

Li J, Aponte Paris S, Thakur H, Kapiloff MS, Dodge-Kafka KL.

J Biol Chem. 2019 Feb 15;294(7):2543-2554. doi: 10.1074/jbc.RA118.005465. Epub 2018 Dec 6.

PMID:
30523159
3.

The scaffold protein muscle A-kinase anchoring protein β orchestrates cardiac myocyte hypertrophic signaling required for the development of heart failure.

Kritzer MD, Li J, Passariello CL, Gayanilo M, Thakur H, Dayan J, Dodge-Kafka K, Kapiloff MS.

Circ Heart Fail. 2014 Jul;7(4):663-72. doi: 10.1161/CIRCHEARTFAILURE.114.001266. Epub 2014 May 8.

4.

CaMKII negatively regulates calcineurin-NFAT signaling in cardiac myocytes.

MacDonnell SM, Weisser-Thomas J, Kubo H, Hanscome M, Liu Q, Jaleel N, Berretta R, Chen X, Brown JH, Sabri AK, Molkentin JD, Houser SR.

Circ Res. 2009 Aug 14;105(4):316-25. doi: 10.1161/CIRCRESAHA.109.194035. Epub 2009 Jul 16.

5.

An adenylyl cyclase-mAKAPbeta signaling complex regulates cAMP levels in cardiac myocytes.

Kapiloff MS, Piggott LA, Sadana R, Li J, Heredia LA, Henson E, Efendiev R, Dessauer CW.

J Biol Chem. 2009 Aug 28;284(35):23540-6. doi: 10.1074/jbc.M109.030072. Epub 2009 Jul 1.

6.

PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling.

Jeong D, Kim JM, Cha H, Oh JG, Park J, Yun SH, Ju ES, Jeon ES, Hajjar RJ, Park WJ.

Circ Res. 2008 Mar 28;102(6):711-9. doi: 10.1161/CIRCRESAHA.107.165985. Epub 2008 Feb 7.

PMID:
18258855
7.

The mAKAP signalosome and cardiac myocyte hypertrophy.

Bauman AL, Michel JJ, Henson E, Dodge-Kafka KL, Kapiloff MS.

IUBMB Life. 2007 Mar;59(3):163-9. Review.

9.

Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes.

Fiedler B, Lohmann SM, Smolenski A, Linnemuller S, Pieske B, Schroder F, Molkentin JD, Drexler H, Wollert KC.

Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11363-8. Epub 2002 Aug 12.

10.

The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signaling.

Pare GC, Bauman AL, McHenry M, Michel JJ, Dodge-Kafka KL, Kapiloff MS.

J Cell Sci. 2005 Dec 1;118(Pt 23):5637-46.

11.

Bidirectional regulation of HDAC5 by mAKAPβ signalosomes in cardiac myocytes.

Dodge-Kafka KL, Gildart M, Li J, Thakur H, Kapiloff MS.

J Mol Cell Cardiol. 2018 May;118:13-25. doi: 10.1016/j.yjmcc.2018.03.001. Epub 2018 Mar 6.

12.

Regulation of MEF2 transcriptional activity by calcineurin/mAKAP complexes.

Li J, Vargas MA, Kapiloff MS, Dodge-Kafka KL.

Exp Cell Res. 2013 Feb 15;319(4):447-54. doi: 10.1016/j.yexcr.2012.12.016. Epub 2012 Dec 21.

13.

Phospholipase C epsilon scaffolds to muscle-specific A kinase anchoring protein (mAKAPbeta) and integrates multiple hypertrophic stimuli in cardiac myocytes.

Zhang L, Malik S, Kelley GG, Kapiloff MS, Smrcka AV.

J Biol Chem. 2011 Jul 1;286(26):23012-21. doi: 10.1074/jbc.M111.231993. Epub 2011 May 5.

14.

Activation of peroxisome proliferator-activated receptor gamma inhibits endothelin-1-induced cardiac hypertrophy via the calcineurin/NFAT signaling pathway.

Bao Y, Li R, Jiang J, Cai B, Gao J, Le K, Zhang F, Chen S, Liu P.

Mol Cell Biochem. 2008 Oct;317(1-2):189-96. doi: 10.1007/s11010-008-9848-8. Epub 2008 Jul 4.

PMID:
18600431
15.

mAKAP-a master scaffold for cardiac remodeling.

Passariello CL, Li J, Dodge-Kafka K, Kapiloff MS.

J Cardiovasc Pharmacol. 2015 Mar;65(3):218-25. doi: 10.1097/FJC.0000000000000206. Review.

16.

Polydatin attenuates cardiac hypertrophy through modulation of cardiac Ca2+ handling and calcineurin-NFAT signaling pathway.

Ding W, Dong M, Deng J, Yan D, Liu Y, Xu T, Liu J.

Am J Physiol Heart Circ Physiol. 2014 Sep 1;307(5):H792-802. doi: 10.1152/ajpheart.00017.2014. Epub 2014 Jul 11.

17.

Astragalus polysaccharide inhibits isoprenaline-induced cardiac hypertrophy via suppressing Ca²⁺-mediated calcineurin/NFATc3 and CaMKII signaling cascades.

Dai H, Jia G, Liu X, Liu Z, Wang H.

Environ Toxicol Pharmacol. 2014 Jul;38(1):263-71. doi: 10.1016/j.etap.2014.05.008. Epub 2014 Jun 13.

PMID:
24975447
18.

Anchored p90 ribosomal S6 kinase 3 is required for cardiac myocyte hypertrophy.

Li J, Kritzer MD, Michel JJ, Le A, Thakur H, Gayanilo M, Passariello CL, Negro A, Danial JB, Oskouei B, Sanders M, Hare JM, Hanauer A, Dodge-Kafka K, Kapiloff MS.

Circ Res. 2013 Jan 4;112(1):128-39. doi: 10.1161/CIRCRESAHA.112.276162. Epub 2012 Sep 20.

19.

The role of mAKAPβ in the process of cardiomyocyte hypertrophy induced by angiotensin II.

Guo H, Liu B, Hou L, The E, Li G, Wang D, Jie Q, Che W, Wei Y.

Int J Mol Med. 2015 May;35(5):1159-68. doi: 10.3892/ijmm.2015.2119. Epub 2015 Mar 2.

20.

Carvedilol reverses cardiac insufficiency in AKAP5 knockout mice by normalizing the activities of calcineurin and CaMKII.

Li X, Matta SM, Sullivan RD, Bahouth SW.

Cardiovasc Res. 2014 Nov 1;104(2):270-9. doi: 10.1093/cvr/cvu209. Epub 2014 Sep 15.

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