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Items: 1 to 20 of 83

1.

Mesalamine inhibits epithelial beta-catenin activation in chronic ulcerative colitis.

Brown JB, Lee G, Managlia E, Grimm GR, Dirisina R, Goretsky T, Cheresh P, Blatner NR, Khazaie K, Yang GY, Li L, Barrett TA.

Gastroenterology. 2010 Feb;138(2):595-605, 605.e1-3. doi: 10.1053/j.gastro.2009.10.038. Epub 2009 Oct 29.

2.

Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis.

Lee G, Goretsky T, Managlia E, Dirisina R, Singh AP, Brown JB, May R, Yang GY, Ragheb JW, Evers BM, Weber CR, Turner JR, He XC, Katzman RB, Li L, Barrett TA.

Gastroenterology. 2010 Sep;139(3):869-81, 881.e1-9. doi: 10.1053/j.gastro.2010.05.037. Epub 2010 May 24.

3.

Antioxidant properties of mesalamine in colitis inhibit phosphoinositide 3-kinase signaling in progenitor cells.

Managlia E, Katzman RB, Brown JB, Barrett TA.

Inflamm Bowel Dis. 2013 Sep;19(10):2051-60. doi: 10.1097/MIB.0b013e318297d741.

PMID:
23867870
4.

Epithelial phosphatidylinositol-3-kinase signaling is required for β-catenin activation and host defense against Citrobacter rodentium infection.

Brown JB, Cheresh P, Goretsky T, Managlia E, Grimm GR, Ryu H, Zadeh M, Dirisina R, Barrett TA.

Infect Immun. 2011 May;79(5):1863-72. doi: 10.1128/IAI.01025-10. Epub 2011 Feb 22.

5.

Modulation of N-glycosylation by mesalamine facilitates membranous E-cadherin expression in colon epithelial cells.

Khare V, Lang M, Dammann K, Campregher C, Lyakhovich A, Gasche C.

Biochem Pharmacol. 2014 Jan 15;87(2):312-20. doi: 10.1016/j.bcp.2013.10.021. Epub 2013 Oct 30.

6.

IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice.

Thaker AI, Rao MS, Bishnupuri KS, Kerr TA, Foster L, Marinshaw JM, Newberry RD, Stenson WF, Ciorba MA.

Gastroenterology. 2013 Aug;145(2):416-25.e1-4. doi: 10.1053/j.gastro.2013.05.002. Epub 2013 May 10.

7.

Beta-catenin pathway in ulcerative colitis-associated colorectal cancer and therapeutic implication.

Chen J, Huang XF.

J Gastrointest Cancer. 2009;40(1-2):64-5. doi: 10.1007/s12029-009-9070-2. Epub 2009 Jun 10. No abstract available.

PMID:
19513862
8.

STAT6 activation in ulcerative colitis: a new target for prevention of IL-13-induced colon epithelial cell dysfunction.

Rosen MJ, Frey MR, Washington MK, Chaturvedi R, Kuhnhein LA, Matta P, Revetta FL, Wilson KT, Polk DB.

Inflamm Bowel Dis. 2011 Nov;17(11):2224-34. doi: 10.1002/ibd.21628. Epub 2011 Feb 9.

9.

The Wnt antagonist Dkk1 regulates intestinal epithelial homeostasis and wound repair.

Koch S, Nava P, Addis C, Kim W, Denning TL, Li L, Parkos CA, Nusrat A.

Gastroenterology. 2011 Jul;141(1):259-68, 268.e1-8. doi: 10.1053/j.gastro.2011.03.043. Epub 2011 Mar 25.

10.
11.

Ergosterol peroxide from Chaga mushroom (Inonotus obliquus) exhibits anti-cancer activity by down-regulation of the β-catenin pathway in colorectal cancer.

Kang JH, Jang JE, Mishra SK, Lee HJ, Nho CW, Shin D, Jin M, Kim MK, Choi C, Oh SH.

J Ethnopharmacol. 2015 Sep 15;173:303-12. doi: 10.1016/j.jep.2015.07.030. Epub 2015 Jul 22.

PMID:
26210065
12.

DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid.

MacFie TS, Poulsom R, Parker A, Warnes G, Boitsova T, Nijhuis A, Suraweera N, Poehlmann A, Szary J, Feakins R, Jeffery R, Harper RW, Jubb AM, Lindsay JO, Silver A.

Inflamm Bowel Dis. 2014 Mar;20(3):514-24. doi: 10.1097/01.MIB.0000442012.45038.0e. Erratum in: Inflamm Bowel Dis. 2014 Apr;20(4):775.

PMID:
24492313
13.

Overexpression of PAK1 promotes cell survival in inflammatory bowel diseases and colitis-associated cancer.

Khare V, Dammann K, Asboth M, Krnjic A, Jambrich M, Gasche C.

Inflamm Bowel Dis. 2015 Feb;21(2):287-96. doi: 10.1097/MIB.0000000000000281.

14.

The influence of 5-aminosalicylic acid on the progression of colorectal adenomas via the β-catenin signaling pathway.

Munding J, Ziebarth W, Pox CP, Ladigan S, Reiser M, Hüppe D, Brand L, Schmiegel W, Tannapfel A, Reinacher-Schick AC.

Carcinogenesis. 2012 Mar;33(3):637-43. doi: 10.1093/carcin/bgr306. Epub 2011 Dec 22.

PMID:
22198215
15.

Expression of interleukin-22/STAT3 signaling pathway in ulcerative colitis and related carcinogenesis.

Yu LZ, Wang HY, Yang SP, Yuan ZP, Xu FY, Sun C, Shi RH.

World J Gastroenterol. 2013 May 7;19(17):2638-49. doi: 10.3748/wjg.v19.i17.2638.

16.

Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1.

Khare V, Lyakhovich A, Dammann K, Lang M, Borgmann M, Tichy B, Pospisilova S, Luciani G, Campregher C, Evstatiev R, Pflueger M, Hundsberger H, Gasche C.

Biochem Pharmacol. 2013 Jan 15;85(2):234-44. doi: 10.1016/j.bcp.2012.10.026. Epub 2012 Nov 9.

17.

Immunohistochemical analysis of retinoblastoma and β-catenin as an assistant tool in the differential diagnosis between Crohn's disease and ulcerative colitis.

Soletti RC, Rodrigues NA, Biasoli D, Luiz RR, de Souza HS, Borges HL.

PLoS One. 2013 Aug 14;8(8):e70786. doi: 10.1371/journal.pone.0070786. eCollection 2013.

18.

Role of miR-150-targeting c-Myb in colonic epithelial disruption during dextran sulphate sodium-induced murine experimental colitis and human ulcerative colitis.

Bian Z, Li L, Cui J, Zhang H, Liu Y, Zhang CY, Zen K.

J Pathol. 2011 Dec;225(4):544-53. doi: 10.1002/path.2907. Epub 2011 May 18.

PMID:
21590770
19.

Effects of AVX-470, an Oral, Locally Acting Anti-Tumour Necrosis Factor Antibody, on Tissue Biomarkers in Patients with Active Ulcerative Colitis.

Hartman DS, Tracey DE, Lemos BR, Erlich EC, Burton RE, Keane DM, Patel R, Kim S, Bhol KC, Harris MS, Fox BS.

J Crohns Colitis. 2016 Jun;10(6):641-9. doi: 10.1093/ecco-jcc/jjw026. Epub 2016 Jan 22.

PMID:
26802087
20.

Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice.

Xiao H, Yin W, Khan MA, Gulen MF, Zhou H, Sham HP, Jacobson K, Vallance BA, Li X.

Gastroenterology. 2010 Aug;139(2):574-85. doi: 10.1053/j.gastro.2010.04.043. Epub 2010 Apr 21.

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