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Membrane type-1 matrix metalloproteinase activity is regulated by the endocytic collagen receptor Endo180.

Messaritou G, East L, Roghi C, Isacke CM, Yarwood H.

J Cell Sci. 2009 Nov 15;122(Pt 22):4042-8. doi: 10.1242/jcs.044305. Epub 2009 Oct 27.


Endo180 expression with cofunctional partners MT1-MMP and uPAR-uPA is correlated with prostate cancer progression.

Kogianni G, Walker MM, Waxman J, Sturge J.

Eur J Cancer. 2009 Mar;45(4):685-93. doi: 10.1016/j.ejca.2008.11.023. Epub 2008 Dec 26.


Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation.

Madsen DH, Engelholm LH, Ingvarsen S, Hillig T, Wagenaar-Miller RA, Kjøller L, Gårdsvoll H, Høyer-Hansen G, Holmbeck K, Bugge TH, Behrendt N.

J Biol Chem. 2007 Sep 14;282(37):27037-45. Epub 2007 Jul 9.


uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion.

Engelholm LH, List K, Netzel-Arnett S, Cukierman E, Mitola DJ, Aaronson H, Kjøller L, Larsen JK, Yamada KM, Strickland DK, Holmbeck K, Danø K, Birkedal-Hansen H, Behrendt N, Bugge TH.

J Cell Biol. 2003 Mar 31;160(7):1009-15.


CD44 enhances invasion of basal-like breast cancer cells by upregulating serine protease and collagen-degrading enzymatic expression and activity.

Montgomery N, Hill A, McFarlane S, Neisen J, O'Grady A, Conlon S, Jirstrom K, Kay EW, Waugh DJ.

Breast Cancer Res. 2012 May 23;14(3):R84.


LRP1 regulates remodeling of the extracellular matrix by fibroblasts.

Gaultier A, Hollister M, Reynolds I, Hsieh EH, Gonias SL.

Matrix Biol. 2010 Jan;29(1):22-30. doi: 10.1016/j.matbio.2009.08.003. Epub 2009 Aug 20.


Claudin promotes activation of pro-matrix metalloproteinase-2 mediated by membrane-type matrix metalloproteinases.

Miyamori H, Takino T, Kobayashi Y, Tokai H, Itoh Y, Seiki M, Sato H.

J Biol Chem. 2001 Jul 27;276(30):28204-11. Epub 2001 May 29.


The urokinase plasminogen activator receptor-associated protein/endo180 is coexpressed with its interaction partners urokinase plasminogen activator receptor and matrix metalloprotease-13 during osteogenesis.

Engelholm LH, Nielsen BS, Netzel-Arnett S, Solberg H, Chen XD, Lopez Garcia JM, Lopez-Otin C, Young MF, Birkedal-Hansen H, Danø K, Lund LR, Behrendt N, Bugge TH.

Lab Invest. 2001 Oct;81(10):1403-14.


Molecular dissection of the structural machinery underlying the tissue-invasive activity of membrane type-1 matrix metalloproteinase.

Li XY, Ota I, Yana I, Sabeh F, Weiss SJ.

Mol Biol Cell. 2008 Aug;19(8):3221-33. doi: 10.1091/mbc.E08-01-0016. Epub 2008 May 21.


Estrogen improves TIMP-MMP balance and collagen distribution in volume-overloaded hearts of ovariectomized females.

Voloshenyuk TG, Gardner JD.

Am J Physiol Regul Integr Comp Physiol. 2010 Aug;299(2):R683-93. doi: 10.1152/ajpregu.00162.2010. Epub 2010 May 26.


Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis.

Jiang A, Lehti K, Wang X, Weiss SJ, Keski-Oja J, Pei D.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13693-8. Epub 2001 Nov 6.


Membrane type I-matrix metalloproteinase-mediated degradation of type I collagen by oral squamous cell carcinoma cells.

Aznavoorian S, Moore BA, Alexander-Lister LD, Hallit SL, Windsor LJ, Engler JA.

Cancer Res. 2001 Aug 15;61(16):6264-75.


MT1-MMP releases latent TGF-beta1 from endothelial cell extracellular matrix via proteolytic processing of LTBP-1.

Tatti O, Vehviläinen P, Lehti K, Keski-Oja J.

Exp Cell Res. 2008 Aug 1;314(13):2501-14. doi: 10.1016/j.yexcr.2008.05.018. Epub 2008 Jun 6.


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