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Items: 1 to 20 of 147

1.

Gene-gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis.

Dervieux T, Wessels JA, van der Straaten T, Penrod N, Moore JH, Guchelaar HJ, Kremer JM.

Pharmacogenet Genomics. 2009 Dec;19(12):935-44. doi: 10.1097/FPC.0b013e32833315d1.

PMID:
19858780
3.

Patterns of interaction between genetic and nongenetic attributes and methotrexate efficacy in rheumatoid arthritis.

Dervieux T, Wessels JA, Kremer JM, Padyukov L, Seddighzadeh M, Saevarsdottir S, van Vollenhoven RF, Klareskog L, Huizinga TW, Guchelaar HJ.

Pharmacogenet Genomics. 2012 Jan;22(1):1-9. doi: 10.1097/FPC.0b013e32834d3e0b.

PMID:
22044941
4.

Common polymorphisms in the folate pathway predict efficacy of combination regimens containing methotrexate and sulfasalazine in early rheumatoid arthritis.

James HM, Gillis D, Hissaria P, Lester S, Somogyi AA, Cleland LG, Proudman SM.

J Rheumatol. 2008 Apr;35(4):562-71. Epub 2008 Mar 1.

PMID:
18322994
5.

Reduced folate carrier-1 80G>A polymorphism affects methotrexate treatment outcome in rheumatoid arthritis.

Drozdzik M, Rudas T, Pawlik A, Gornik W, Kurzawski M, Herczynska M.

Pharmacogenomics J. 2007 Dec;7(6):404-7. Epub 2007 Feb 27.

PMID:
17325736
6.
7.

Homocysteine and folate status in methotrexate-treated patients with rheumatoid arthritis.

van Ede AE, Laan RF, Blom HJ, Boers GH, Haagsma CJ, Thomas CM, De Boo TM, van de Putte LB.

Rheumatology (Oxford). 2002 Jun;41(6):658-65.

PMID:
12048292
8.

Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis.

Weisman MH, Furst DE, Park GS, Kremer JM, Smith KM, Wallace DJ, Caldwell JR, Dervieux T.

Arthritis Rheum. 2006 Feb;54(2):607-12.

9.

Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.

Wessels JA, de Vries-Bouwstra JK, Heijmans BT, Slagboom PE, Goekoop-Ruiterman YP, Allaart CF, Kerstens PJ, van Zeben D, Breedveld FC, Dijkmans BA, Huizinga TW, Guchelaar HJ.

Arthritis Rheum. 2006 Apr;54(4):1087-95.

10.

2756GG genotype of methionine synthase reductase gene is more prevalent in rheumatoid arthritis patients treated with methotrexate and is associated with methotrexate-induced nodulosis.

Berkun Y, Abou Atta I, Rubinow A, Orbach H, Levartovsky D, Aamar S, Arbel O, Dresner-Pollak R, Friedman G, Ben-Yehuda A.

J Rheumatol. 2007 Aug;34(8):1664-9. Epub 2007 Jul 1.

PMID:
17611986
12.

Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis.

Wessels JA, Kooloos WM, De Jonge R, De Vries-Bouwstra JK, Allaart CF, Linssen A, Collee G, De Sonnaville P, Lindemans J, Huizinga TW, Guchelaar HJ.

Arthritis Rheum. 2006 Sep;54(9):2830-9.

14.

Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate.

Stamp LK, Chapman PT, O'Donnell JL, Zhang M, James J, Frampton C, Barclay ML, Kennedy MA, Roberts RL.

Pharmacogenet Genomics. 2010 Jun;20(6):367-76. doi: 10.1097/FPC.0b013e3283398a71.

PMID:
20386493
15.
16.
17.

Association of dihydrofolate reductase (DHFR) -317AA genotype with poor response to methotrexate in patients with rheumatoid arthritis.

Milic V, Jekic B, Lukovic L, Bunjevacki V, Milasin J, Novakovic I, Damnjanovic T, Popovic B, Maksimovic N, Damjanov N, Radunovic G, Pejnovic N, Krajinovic M.

Clin Exp Rheumatol. 2012 Mar-Apr;30(2):178-83. Epub 2012 Apr 13.

PMID:
22324981
18.

The C677T mutation in the methylenetetrahydrofolate reductase gene: a genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients.

van Ede AE, Laan RF, Blom HJ, Huizinga TW, Haagsma CJ, Giesendorf BA, de Boo TM, van de Putte LB.

Arthritis Rheum. 2001 Nov;44(11):2525-30.

PMID:
11710708
19.

The C677T polymorphism in the MTHFR gene is associated with the toxicity of methotrexate in a Spanish rheumatoid arthritis population.

Cáliz R, del Amo J, Balsa A, Blanco F, Silva L, Sanmarti R, Martínez FG, Collado MD, Ramirez Mdel C, Tejedor D, Artieda M, Pascual-Salcedo D, Oreiro N, Andreu JL, Graell E, Simon L, Martínez A, Mulero J.

Scand J Rheumatol. 2012 Feb;41(1):10-4. doi: 10.3109/03009742.2011.617312. Epub 2011 Nov 1.

PMID:
22044028
20.

Association of the TYMS 3G/3G genotype with poor response and GGH 354GG genotype with the bone marrow toxicity of the methotrexate in RA patients.

Jekic B, Lukovic L, Bunjevacki V, Milic V, Novakovic I, Damnjanovic T, Milasin J, Popovic B, Maksimovic N, Damjanov N, Radunovic G, Kovacevic L, Krajinovic M.

Eur J Clin Pharmacol. 2013 Mar;69(3):377-83. doi: 10.1007/s00228-012-1341-3. Epub 2012 Jul 5.

PMID:
22763757

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