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Items: 1 to 20 of 111

1.

Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression.

Palakurthy RK, Wajapeyee N, Santra MK, Gazin C, Lin L, Gobeil S, Green MR.

Mol Cell. 2009 Oct 23;36(2):219-30. doi: 10.1016/j.molcel.2009.10.009.

2.

Mahanine restores RASSF1A expression by down-regulating DNMT1 and DNMT3B in prostate cancer cells.

Agarwal S, Amin KS, Jagadeesh S, Baishay G, Rao PG, Barua NC, Bhattacharya S, Banerjee PP.

Mol Cancer. 2013 Aug 30;12(1):99. doi: 10.1186/1476-4598-12-99.

3.

The intronic long noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, reducing the expression of RASSF1A and increasing cell proliferation.

Beckedorff FC, Ayupe AC, Crocci-Souza R, Amaral MS, Nakaya HI, Soltys DT, Menck CF, Reis EM, Verjovski-Almeida S.

PLoS Genet. 2013;9(8):e1003705. doi: 10.1371/journal.pgen.1003705. Epub 2013 Aug 22.

4.

Delta DNMT3B variants regulate DNA methylation in a promoter-specific manner.

Wang J, Bhutani M, Pathak AK, Lang W, Ren H, Jelinek J, He R, Shen L, Issa JP, Mao L.

Cancer Res. 2007 Nov 15;67(22):10647-52.

5.

The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix.

Cohen Y, Singer G, Lavie O, Dong SM, Beller U, Sidransky D.

Clin Cancer Res. 2003 Aug 1;9(8):2981-4.

6.

Critical role of deltaDNMT3B4/2 in regulating RASSF1A promoter-specific DNA methylation in non-small cell lung cancer.

Wang SH, Liu NH, Wang J, Bai H, Mao L.

Chin Med J (Engl). 2008 Sep 5;121(17):1712-21.

PMID:
19024105
7.

Mahanine reverses an epigenetically silenced tumor suppressor gene RASSF1A in human prostate cancer cells.

Jagadeesh S, Sinha S, Pal BC, Bhattacharya S, Banerjee PP.

Biochem Biophys Res Commun. 2007 Oct 12;362(1):212-7. Epub 2007 Aug 9.

PMID:
17698033
8.

Expression of RASSF1A, an epigenetically silenced tumor suppressor, overcomes resistance to apoptosis induction by interferons.

Reu FJ, Leaman DW, Maitra RR, Bae SI, Cherkassky L, Fox MW, Rempinski DR, Beaulieu N, MacLeod AR, Borden EC.

Cancer Res. 2006 Mar 1;66(5):2785-93.

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MYCN is recruited to the RASSF1A promoter but is not critical for DNA hypermethylation in neuroblastoma.

Charlet J, Szemes M, Malik KT, Brown KW.

Mol Carcinog. 2014 May;53(5):413-20. doi: 10.1002/mc.21994. Epub 2012 Dec 31.

PMID:
23280764
11.

Upregulation of DNMT1 mediated by HBx suppresses RASSF1A expression independent of DNA methylation.

Qiu X, Zhang L, Lu S, Song Y, Lao Y, Hu J, Fan H.

Oncol Rep. 2014 Jan;31(1):202-8. doi: 10.3892/or.2013.2848. Epub 2013 Nov 14.

PMID:
24247422
12.

Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer.

Ai L, Tao Q, Zhong S, Fields CR, Kim WJ, Lee MW, Cui Y, Brown KD, Robertson KD.

Carcinogenesis. 2006 Jul;27(7):1341-8. Epub 2006 Feb 25.

14.

Epigenetic inactivation of the RASSF1A 3p21.3 tumor suppressor gene in both clear cell and papillary renal cell carcinoma.

Morrissey C, Martinez A, Zatyka M, Agathanggelou A, Honorio S, Astuti D, Morgan NV, Moch H, Richards FM, Kishida T, Yao M, Schraml P, Latif F, Maher ER.

Cancer Res. 2001 Oct 1;61(19):7277-81.

15.

Epigenetic silencing of RASSF1A deregulates cytoskeleton and promotes malignant behavior of adrenocortical carcinoma.

Korah R, Healy JM, Kunstman JW, Fonseca AL, Ameri AH, Prasad ML, Carling T.

Mol Cancer. 2013 Aug 5;12:87. doi: 10.1186/1476-4598-12-87.

16.

Re-expression of RASSF1A by 5-Aza-CdR induced demethylation of the promoter region in human biliary tract carcinoma cells.

Zuo S, Chen Y, Xu L, Tang Q, Zou S.

J Huazhong Univ Sci Technolog Med Sci. 2007 Jun;27(3):281-4.

PMID:
17641842
17.

Global identification of genes targeted by DNMT3b for epigenetic silencing in lung cancer.

Teneng I, Tellez CS, Picchi MA, Klinge DM, Yingling CM, Snider AM, Liu Y, Belinsky SA.

Oncogene. 2015 Jan 29;34(5):621-30. doi: 10.1038/onc.2013.580. Epub 2014 Jan 27.

PMID:
24469050
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20.

Methylation associated inactivation of RASSF1A and its synergistic effect with activated K-Ras in nasopharyngeal carcinoma.

Wang T, Liu H, Chen Y, Liu W, Yu J, Wu G.

J Exp Clin Cancer Res. 2009 Dec 30;28:160. doi: 10.1186/1756-9966-28-160.

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