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Items: 1 to 20 of 73

1.

Role of muscle c-Jun NH2-terminal kinase 1 in obesity-induced insulin resistance.

Sabio G, Kennedy NJ, Cavanagh-Kyros J, Jung DY, Ko HJ, Ong H, Barrett T, Kim JK, Davis RJ.

Mol Cell Biol. 2010 Jan;30(1):106-15. doi: 10.1128/MCB.01162-09.

2.

Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance.

Singh R, Wang Y, Xiang Y, Tanaka KE, Gaarde WA, Czaja MJ.

Hepatology. 2009 Jan;49(1):87-96. doi: 10.1002/hep.22578.

3.
4.

Chronic blockade of nitric oxide synthesis reduces adiposity and improves insulin resistance in high fat-induced obese mice.

Tsuchiya K, Sakai H, Suzuki N, Iwashima F, Yoshimoto T, Shichiri M, Hirata Y.

Endocrinology. 2007 Oct;148(10):4548-56. Epub 2007 Jun 21.

PMID:
17584959
5.

A stress signaling pathway in adipose tissue regulates hepatic insulin resistance.

Sabio G, Das M, Mora A, Zhang Z, Jun JY, Ko HJ, Barrett T, Kim JK, Davis RJ.

Science. 2008 Dec 5;322(5907):1539-43. doi: 10.1126/science.1160794.

6.

Substance P (SP)-neurokinin-1 receptor (NK-1R) alters adipose tissue responses to high-fat diet and insulin action.

Karagiannides I, Stavrakis D, Bakirtzi K, Kokkotou E, Pirtskhalava T, Nayeb-Hashemi H, Bowe C, Bugni JM, Nuño M, Lu B, Gerard NP, Leeman SE, Kirkland JL, Pothoulakis C.

Endocrinology. 2011 Jun;152(6):2197-205. doi: 10.1210/en.2010-1345. Epub 2011 Apr 5.

7.

JNK1 ablation in mice confers long-term metabolic protection from diet-induced obesity at the cost of moderate skin oxidative damage.

Becattini B, Zani F, Breasson L, Sardi C, D'Agostino VG, Choo MK, Provenzani A, Park JM, Solinas G.

FASEB J. 2016 Sep;30(9):3124-32. doi: 10.1096/fj.201600393R. Epub 2016 May 26.

8.

cJun NH2-terminal kinase 1 (JNK1): roles in metabolic regulation of insulin resistance.

Sabio G, Davis RJ.

Trends Biochem Sci. 2010 Sep;35(9):490-6. doi: 10.1016/j.tibs.2010.04.004. Epub 2010 May 7. Review.

9.

AMPK-α2 is involved in exercise training-induced adaptations in insulin-stimulated metabolism in skeletal muscle following high-fat diet.

Abbott MJ, Turcotte LP.

J Appl Physiol (1985). 2014 Oct 15;117(8):869-79. doi: 10.1152/japplphysiol.01380.2013. Epub 2014 Aug 7.

10.

c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-kappaB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals.

Sourris KC, Lyons JG, de Courten MP, Dougherty SL, Henstridge DC, Cooper ME, Hage M, Dart A, Kingwell BA, Forbes JM, de Courten B.

Diabetes. 2009 Jun;58(6):1259-65. doi: 10.2337/db08-1725. Epub 2009 Mar 3.

11.

Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice.

Pal M, Wunderlich CM, Spohn G, Brönneke HS, Schmidt-Supprian M, Wunderlich FT.

PLoS One. 2013;8(1):e54247. doi: 10.1371/journal.pone.0054247. Epub 2013 Jan 17.

12.

Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart.

Park SY, Kim HJ, Wang S, Higashimori T, Dong J, Kim YJ, Cline G, Li H, Prentki M, Shulman GI, Mitchell GA, Kim JK.

Am J Physiol Endocrinol Metab. 2005 Jul;289(1):E30-9. Epub 2005 Feb 8.

13.

Inflammation is necessary for long-term but not short-term high-fat diet-induced insulin resistance.

Lee YS, Li P, Huh JY, Hwang IJ, Lu M, Kim JI, Ham M, Talukdar S, Chen A, Lu WJ, Bandyopadhyay GK, Schwendener R, Olefsky J, Kim JB.

Diabetes. 2011 Oct;60(10):2474-83. doi: 10.2337/db11-0194. Epub 2011 Sep 12.

14.

Novel roles for JNK1 in metabolism.

Belgardt BF, Mauer J, Brüning JC.

Aging (Albany NY). 2010 Sep;2(9):621-6.

15.

Attenuated adipose tissue and skeletal muscle inflammation in obese mice with combined CD4+ and CD8+ T cell deficiency.

Khan IM, Dai Perrard XY, Perrard JL, Mansoori A, Smith CW, Wu H, Ballantyne CM.

Atherosclerosis. 2014 Apr;233(2):419-28. doi: 10.1016/j.atherosclerosis.2014.01.011. Epub 2014 Jan 21.

16.

Disruption of CXC motif chemokine ligand-14 in mice ameliorates obesity-induced insulin resistance.

Nara N, Nakayama Y, Okamoto S, Tamura H, Kiyono M, Muraoka M, Tanaka K, Taya C, Shitara H, Ishii R, Yonekawa H, Minokoshi Y, Hara T.

J Biol Chem. 2007 Oct 19;282(42):30794-803. Epub 2007 Aug 27.

17.

12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice.

Sears DD, Miles PD, Chapman J, Ofrecio JM, Almazan F, Thapar D, Miller YI.

PLoS One. 2009 Sep 29;4(9):e7250. doi: 10.1371/journal.pone.0007250.

18.

Prevention of steatosis by hepatic JNK1.

Sabio G, Cavanagh-Kyros J, Ko HJ, Jung DY, Gray S, Jun JY, Barrett T, Mora A, Kim JK, Davis RJ.

Cell Metab. 2009 Dec;10(6):491-8. doi: 10.1016/j.cmet.2009.09.007.

19.

Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance.

Tuncman G, Hirosumi J, Solinas G, Chang L, Karin M, Hotamisligil GS.

Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10741-6. Epub 2006 Jul 3.

20.

Protein tyrosine phosphatase 1B and insulin resistance: role of endoplasmic reticulum stress/reactive oxygen species/nuclear factor kappa B axis.

Panzhinskiy E, Ren J, Nair S.

PLoS One. 2013 Oct 18;8(10):e77228. doi: 10.1371/journal.pone.0077228. eCollection 2013.

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