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Items: 1 to 20 of 221

1.

Modeling kinetics of a large-scale fed-batch CHO cell culture by Markov chain Monte Carlo method.

Xing Z, Bishop N, Leister K, Li ZJ.

Biotechnol Prog. 2010 Jan-Feb;26(1):208-19. doi: 10.1002/btpr.284.

PMID:
19834967
2.

Feed development for fed-batch CHO production process by semisteady state analysis.

Khattak SF, Xing Z, Kenty B, Koyrakh I, Li ZJ.

Biotechnol Prog. 2010 May-Jun;26(3):797-804. doi: 10.1002/btpr.362.

PMID:
20014108
3.

Process model comparison and transferability across bioreactor scales and modes of operation for a mammalian cell bioprocess.

Craven S, Shirsat N, Whelan J, Glennon B.

Biotechnol Prog. 2013 Jan-Feb;29(1):186-96. doi: 10.1002/btpr.1664. Epub 2012 Dec 20.

PMID:
23143896
4.

Identifying inhibitory threshold values of repressing metabolites in CHO cell culture using multivariate analysis methods.

Xing Z, Li Z, Chow V, Lee SS.

Biotechnol Prog. 2008 May-Jun;24(3):675-83. doi: 10.1021/bp070466m. Epub 2008 Apr 19.

PMID:
18422365
5.

Low-glutamine fed-batch cultures of 293-HEK serum-free suspension cells for adenovirus production.

Lee YY, Yap MG, Hu WS, Wong KT.

Biotechnol Prog. 2003 Mar-Apr;19(2):501-9.

PMID:
12675594
6.

High-end pH-controlled delivery of glucose effectively suppresses lactate accumulation in CHO fed-batch cultures.

Gagnon M, Hiller G, Luan YT, Kittredge A, DeFelice J, Drapeau D.

Biotechnol Bioeng. 2011 Jun;108(6):1328-37. doi: 10.1002/bit.23072. Epub 2011 Feb 24.

PMID:
21328318
7.

Logistic equations effectively model Mammalian cell batch and fed-batch kinetics by logically constraining the fit.

Goudar CT, Joeris K, Konstantinov KB, Piret JM.

Biotechnol Prog. 2005 Jul-Aug;21(4):1109-18.

PMID:
16080690
8.

Growth behavior of Chinese hamster ovary cells in a compact loop bioreactor. 2. Effects of medium components and waste products.

Kurano N, Leist C, Messi F, Kurano S, Fiechter A.

J Biotechnol. 1990 Jul;15(1-2):113-28.

PMID:
1366684
9.

Human 293 cell metabolism in low glutamine-supplied culture: interpretation of metabolic changes through metabolic flux analysis.

Nadeau I, Sabatié J, Koehl M, Perrier M, Kamen A.

Metab Eng. 2000 Oct;2(4):277-92.

PMID:
11120640
10.

A single nutrient feed supports both chemically defined NS0 and CHO fed-batch processes: Improved productivity and lactate metabolism.

Ma N, Ellet J, Okediadi C, Hermes P, McCormick E, Casnocha S.

Biotechnol Prog. 2009 Sep-Oct;25(5):1353-63. doi: 10.1002/btpr.238.

PMID:
19637321
11.

Heuristic optimization of antibody production by Chinese hamster ovary cells.

Sandadi S, Ensari S, Kearns B.

Biotechnol Prog. 2005 Sep-Oct;21(5):1537-42.

PMID:
16209559
12.

Impact of dynamic online fed-batch strategies on metabolism, productivity and N-glycosylation quality in CHO cell cultures.

Chee Furng Wong D, Tin Kam Wong K, Tang Goh L, Kiat Heng C, Gek Sim Yap M.

Biotechnol Bioeng. 2005 Jan 20;89(2):164-77.

PMID:
15593097
13.

Robust parameter estimation during logistic modeling of batch and fed-batch culture kinetics.

Goudar CT, Konstantinov KB, Piret JM.

Biotechnol Prog. 2009 May-Jun;25(3):801-6. doi: 10.1002/btpr.154.

PMID:
19496143
14.

Development of a fed-batch culture process for enhanced production of recombinant human antithrombin by Chinese hamster ovary cells.

Kuwae S, Ohda T, Tamashima H, Miki H, Kobayashi K.

J Biosci Bioeng. 2005 Nov;100(5):502-10.

PMID:
16384788
15.

A novel control scheme for inducing angiostatin-human IgG fusion protein production using recombinant CHO cells in a oscillating bioreactor.

Wang IK, Hsieh SY, Chang KM, Wang YC, Chu A, Shaw SY, Ou JJ, Ho L.

J Biotechnol. 2006 Feb 10;121(3):418-28. Epub 2005 Sep 12.

PMID:
16162365
16.

Metabolic flux analysis in mammalian cell culture.

Quek LE, Dietmair S, Krömer JO, Nielsen LK.

Metab Eng. 2010 Mar;12(2):161-71. doi: 10.1016/j.ymben.2009.09.002. Epub 2009 Oct 13. Review.

PMID:
19833223
17.

Fed-batch CHO cell t-PA production and feed glutamine replacement to reduce ammonia production.

Kim DY, Chaudhry MA, Kennard ML, Jardon MA, Braasch K, Dionne B, Butler M, Piret JM.

Biotechnol Prog. 2013 Jan-Feb;29(1):165-75. doi: 10.1002/btpr.1658. Epub 2012 Dec 4.

PMID:
23125190
18.

Overexpression of taurine transporter in Chinese hamster ovary cells can enhance cell viability and product yield, while promoting glutamine consumption.

Tabuchi H, Sugiyama T, Tanaka S, Tainaka S.

Biotechnol Bioeng. 2010 Dec 15;107(6):998-1003. doi: 10.1002/bit.22880.

PMID:
20661907
19.

Metabolic shifts by nutrient manipulation in continuous cultures of BHK cells.

Cruz HJ, Moreira JL, Carrondo MJ.

Biotechnol Bioeng. 1999;66(2):104-13.

PMID:
10567068
20.

Metabolism of PER.C6 cells cultivated under fed-batch conditions at low glucose and glutamine levels.

Maranga L, Goochee CF.

Biotechnol Bioeng. 2006 May 5;94(1):139-50.

PMID:
16523524

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