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Tauroursodeoxycholic acid attenuates lipid accumulation in endoplasmic reticulum-stressed macrophages.

Hua Y, Kandadi MR, Zhu M, Ren J, Sreejayan N.

J Cardiovasc Pharmacol. 2010 Jan;55(1):49-55. doi: 10.1097/FJC.0b013e3181c37d86.


Ethanol extract of propolis protects macrophages from oxidized low density lipoprotein-induced apoptosis by inhibiting CD36 expression and endoplasmic reticulum stress-C/EBP homologous protein pathway.

Tian H, Sun HW, Zhang JJ, Zhang XW, Zhao L, Guo SD, Li YY, Jiao P, Wang H, Qin SC, Yao ST.

BMC Complement Altern Med. 2015 Jul 14;15:230. doi: 10.1186/s12906-015-0759-4.


Endoplasmic reticulum stress upregulates protein tyrosine phosphatase 1B and impairs glucose uptake in cultured myotubes.

Panzhinskiy E, Hua Y, Culver B, Ren J, Nair S.

Diabetologia. 2013 Mar;56(3):598-607. doi: 10.1007/s00125-012-2782-z. Epub 2012 Nov 24.


D4F alleviates macrophage-derived foam cell apoptosis by inhibiting CD36 expression and ER stress-CHOP pathway.

Yao S, Tian H, Miao C, Zhang DW, Zhao L, Li Y, Yang N, Jiao P, Sang H, Guo S, Wang Y, Qin S.

J Lipid Res. 2015 Apr;56(4):836-47. doi: 10.1194/jlr.M055400. Epub 2015 Jan 29.


Endoplasmic reticulum chaperon tauroursodeoxycholic acid alleviates obesity-induced myocardial contractile dysfunction.

Ceylan-Isik AF, Sreejayan N, Ren J.

J Mol Cell Cardiol. 2011 Jan;50(1):107-16. doi: 10.1016/j.yjmcc.2010.10.023. Epub 2010 Oct 28.


Chronic inhibition of endoplasmic reticulum stress and inflammation prevents ischaemia-induced vascular pathology in type II diabetic mice.

Amin A, Choi SK, Galan M, Kassan M, Partyka M, Kadowitz P, Henrion D, Trebak M, Belmadani S, Matrougui K.

J Pathol. 2012 Jun;227(2):165-74. doi: 10.1002/path.3960. Epub 2012 Feb 17.


Endoplasmic reticulum stress participates in aortic valve calcification in hypercholesterolemic animals.

Cai Z, Li F, Gong W, Liu W, Duan Q, Chen C, Ni L, Xia Y, Cianflone K, Dong N, Wang DW.

Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2345-54. doi: 10.1161/ATVBAHA.112.300226. Epub 2013 Aug 8.


Quercetin protects macrophages from oxidized low-density lipoprotein-induced apoptosis by inhibiting the endoplasmic reticulum stress-C/EBP homologous protein pathway.

Yao S, Sang H, Song G, Yang N, Liu Q, Zhang Y, Jiao P, Zong C, Qin S.

Exp Biol Med (Maywood). 2012 Jul;237(7):822-31. doi: 10.1258/ebm.2012.012027. Epub 2012 Jul 24. Erratum in: Exp Biol Med (Maywood). 2013 Jan 1;238(1):125.


FFA-induced adipocyte inflammation and insulin resistance: involvement of ER stress and IKKβ pathways.

Jiao P, Ma J, Feng B, Zhang H, Diehl JA, Chin YE, Yan W, Xu H.

Obesity (Silver Spring). 2011 Mar;19(3):483-91. doi: 10.1038/oby.2010.200. Epub 2010 Sep 9.


[Oxidized low density lipoprotein induces macrophage endoplasmic reticulum stress via CD36.].

Yao ST, Sang H, Yang NN, Kang L, Tian H, Zhang Y, Song GH, Qin SC.

Sheng Li Xue Bao. 2010 Oct 25;62(5):433-40. Chinese.


Tauroursodeoxycholic acid mitigates high fat diet-induced cardiomyocyte contractile and intracellular Ca2+ anomalies.

Turdi S, Hu N, Ren J.

PLoS One. 2013 May 7;8(5):e63615. doi: 10.1371/journal.pone.0063615. Print 2013. Erratum in: PLoS One. 2016;11(4):e0154907.


The role of tauroursodeoxycholic acid on adipogenesis of human adipose-derived stem cells by modulation of ER stress.

Cha BH, Kim JS, Ahn JC, Kim HC, Kim BS, Han DK, Park SG, Lee SH.

Biomaterials. 2014 Mar;35(9):2851-8. doi: 10.1016/j.biomaterials.2013.12.067. Epub 2014 Jan 11.


Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, acinar cell damage, and systemic inflammation in acute pancreatitis.

Seyhun E, Malo A, Schäfer C, Moskaluk CA, Hoffmann RT, Göke B, Kubisch CH.

Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G773-82. doi: 10.1152/ajpgi.00483.2010. Epub 2011 Jul 21.


Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure.

Vandewynckel YP, Laukens D, Devisscher L, Paridaens A, Bogaerts E, Verhelst X, Van den Bussche A, Raevens S, Van Steenkiste C, Van Troys M, Ampe C, Descamps B, Vanhove C, Govaere O, Geerts A, Van Vlierberghe H.

Oncotarget. 2015 Sep 29;6(29):28011-25. doi: 10.18632/oncotarget.4377.


Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, trypsin activation, and acinar cell apoptosis while increasing secretion in rat pancreatic acini.

Malo A, Krüger B, Seyhun E, Schäfer C, Hoffmann RT, Göke B, Kubisch CH.

Am J Physiol Gastrointest Liver Physiol. 2010 Oct;299(4):G877-86. doi: 10.1152/ajpgi.00423.2009. Epub 2010 Jul 29.


HDL inhibits endoplasmic reticulum stress by stimulating apoE and CETP secretion from lipid-loaded macrophages.

Niculescu LS, Sanda GM, Sima AV.

Biochem Biophys Res Commun. 2013 Apr 26;434(1):173-8. doi: 10.1016/j.bbrc.2013.03.050. Epub 2013 Mar 26.


Protein tyrosine phosphatase 1B and insulin resistance: role of endoplasmic reticulum stress/reactive oxygen species/nuclear factor kappa B axis.

Panzhinskiy E, Ren J, Nair S.

PLoS One. 2013 Oct 18;8(10):e77228. doi: 10.1371/journal.pone.0077228. eCollection 2013.


Structure-function analysis of the tertiary bile acid TUDCA for the resolution of endoplasmic reticulum stress in intestinal epithelial cells.

Berger E, Haller D.

Biochem Biophys Res Commun. 2011 Jun 17;409(4):610-5. doi: 10.1016/j.bbrc.2011.05.043. Epub 2011 May 14.


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