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Items: 1 to 20 of 93

1.

Trans-presentation: a novel mechanism regulating IL-15 delivery and responses.

Stonier SW, Schluns KS.

Immunol Lett. 2010 Jan 4;127(2):85-92. doi: 10.1016/j.imlet.2009.09.009. Epub 2009 Oct 7. Review.

2.

The roles of interleukin-15 receptor alpha: trans-presentation, receptor component, or both?

Schluns KS, Stoklasek T, Lefrançois L.

Int J Biochem Cell Biol. 2005 Aug;37(8):1567-71. Epub 2005 Mar 5. Review.

PMID:
15896666
3.

Different dynamics of IL-15R activation following IL-15 cis- or trans-presentation.

Perdreau H, Mortier E, Bouchaud G, Solé V, Boublik Y, Plet A, Jacques Y.

Eur Cytokine Netw. 2010 Dec;21(4):297-307. doi: 10.1684/ecn.2010.0207. Epub 2010 Nov 16.

4.

No requirement of trans presentations of IL-15 for human CD8 T cell proliferation.

Ota N, Takase M, Uchiyama H, Olsen SK, Kanagawa O.

J Immunol. 2010 Nov 15;185(10):6041-8. doi: 10.4049/jimmunol.0901834. Epub 2010 Oct 6.

5.

Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis.

Ma A, Koka R, Burkett P.

Annu Rev Immunol. 2006;24:657-79. Review.

PMID:
16551262
6.

Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo.

Kraynyak KA, Kutzler MA, Cisper NJ, Laddy DJ, Morrow MP, Waldmann TA, Weiner DB.

Hum Gene Ther. 2009 Oct;20(10):1143-56. doi: 10.1089/hum.2009.025.

7.
8.

IL-15.IL-15Rα complex shedding following trans-presentation is essential for the survival of IL-15 responding NK and T cells.

Tamzalit F, Barbieux I, Plet A, Heim J, Nedellec S, Morisseau S, Jacques Y, Mortier E.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8565-70. doi: 10.1073/pnas.1405514111. Epub 2014 May 27.

9.

Increasing the biological activity of IL-2 and IL-15 through complexing with anti-IL-2 mAbs and IL-15Rα-Fc chimera.

Votavova P, Tomala J, Kovar M.

Immunol Lett. 2014 May-Jun;159(1-2):1-10. doi: 10.1016/j.imlet.2014.01.017. Epub 2014 Feb 7. Review.

PMID:
24512738
10.

IL-15 can signal via IL-15Rα, JNK, and NF-κB to drive RANTES production by myeloid cells.

Chenoweth MJ, Mian MF, Barra NG, Alain T, Sonenberg N, Bramson J, Lichty BD, Richards CD, Ma A, Ashkar AA.

J Immunol. 2012 May 1;188(9):4149-57. doi: 10.4049/jimmunol.1101883. Epub 2012 Mar 23.

11.

Macrophage- and dendritic-cell-derived interleukin-15 receptor alpha supports homeostasis of distinct CD8+ T cell subsets.

Mortier E, Advincula R, Kim L, Chmura S, Barrera J, Reizis B, Malynn BA, Ma A.

Immunity. 2009 Nov 20;31(5):811-22. doi: 10.1016/j.immuni.2009.09.017. Epub 2009 Nov 12.

12.

Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis.

Burkett PR, Koka R, Chien M, Chai S, Boone DL, Ma A.

J Exp Med. 2004 Oct 4;200(7):825-34. Epub 2004 Sep 27.

13.

Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins.

Mortier E, Quéméner A, Vusio P, Lorenzen I, Boublik Y, Grötzinger J, Plet A, Jacques Y.

J Biol Chem. 2006 Jan 20;281(3):1612-9. Epub 2005 Nov 11.

14.

Distinct cell types control lymphoid subset development by means of IL-15 and IL-15 receptor alpha expression.

Schluns KS, Nowak EC, Cabrera-Hernandez A, Puddington L, Lefrançois L, Aguila HL.

Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5616-21. Epub 2004 Apr 1.

15.

[Biology and immunotherapy advance of interleukin 2 and interleukin 15-review].

Chen GH, Wu DP.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Aug;17(4):1088-92. Review. Chinese.

PMID:
19698267
16.

A programmed switch from IL-15- to IL-2-dependent activation in human NK cells.

Pillet AH, Bugault F, Thèze J, Chakrabarti LA, Rose T.

J Immunol. 2009 May 15;182(10):6267-77. doi: 10.4049/jimmunol.0801933.

17.

Interleukin-15 as a potential regulator of the innate immune response.

Carson W, Caligiuri MA.

Braz J Med Biol Res. 1998 Jan;31(1):1-9. Review.

PMID:
9686173
18.

Crystal Structure of the interleukin-15.interleukin-15 receptor alpha complex: insights into trans and cis presentation.

Olsen SK, Ota N, Kishishita S, Kukimoto-Niino M, Murayama K, Uchiyama H, Toyama M, Terada T, Shirouzu M, Kanagawa O, Yokoyama S.

J Biol Chem. 2007 Dec 21;282(51):37191-204. Epub 2007 Oct 18.

19.
20.

The IL-15 receptor {alpha} chain cytoplasmic domain is critical for normal IL-15Ralpha function but is not required for trans-presentation.

Wu Z, Xue HH, Bernard J, Zeng R, Issakov D, Bollenbacher-Reilley J, Belyakov IM, Oh S, Berzofsky JA, Leonard WJ.

Blood. 2008 Dec 1;112(12):4411-9. doi: 10.1182/blood-2007-03-080697. Epub 2008 Sep 16.

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