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Items: 1 to 20 of 176

1.

Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes.

Patrick MS, Oda H, Hayakawa K, Sato Y, Eshima K, Kirikae T, Iemura S, Shirai M, Abe T, Natsume T, Sasazuki T, Suzuki H.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16345-50. doi: 10.1073/pnas.0908593106.

3.

RasGRP1 transmits prodifferentiation TCR signaling that is crucial for CD4 T cell development.

Priatel JJ, Chen X, Dhanji S, Abraham N, Teh HS.

J Immunol. 2006 Aug 1;177(3):1470-80.

4.

Thymocyte-specific truncation of the deubiquitinating domain of CYLD impairs positive selection in a NF-kappaB essential modulator-dependent manner.

Tsagaratou A, Trompouki E, Grammenoudi S, Kontoyiannis DL, Mosialos G.

J Immunol. 2010 Aug 15;185(4):2032-43. doi: 10.4049/jimmunol.0903919.

5.

Expression of 4-1BB and 4-1BBL in thymocytes during thymus regeneration.

Kim YM, Kim HK, Kim HJ, Lee HW, Ju SA, Choi BK, Kwon BS, Kim BS, Kim JB, Lim YT, Yoon S.

Exp Mol Med. 2009 Dec 31;41(12):896-911. doi: 10.3858/emm.2009.41.12.095.

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Thymocyte-intrinsic genetic factors influence CD8 T cell lineage commitment and affect selection of a tumor-reactive TCR.

Shanker A, Auphan-Anezin N, Chomez P, Giraudo L, Van den Eynde B, Schmitt-Verhulst AM.

J Immunol. 2004 Apr 15;172(8):5069-77.

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Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength.

Izon DJ, Punt JA, Xu L, Karnell FG, Allman D, Myung PS, Boerth NJ, Pui JC, Koretzky GA, Pear WS.

Immunity. 2001 Mar;14(3):253-64.

13.

Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling.

Wang D, Zheng M, Lei L, Ji J, Yao Y, Qiu Y, Ma L, Lou J, Ouyang C, Zhang X, He Y, Chi J, Wang L, Kuang Y, Wang J, Cao X, Lu L.

Nat Immunol. 2012 May 6;13(6):560-8. doi: 10.1038/ni.2301.

PMID:
22561606
14.

The quantity of TCR signal determines positive selection and lineage commitment of T cells.

Watanabe N, Arase H, Onodera M, Ohashi PS, Saito T.

J Immunol. 2000 Dec 1;165(11):6252-61.

15.

Early growth response (Egr)-1 gene induction in the thymus in response to TCR ligation during early steps in positive selection is not required for CD8 lineage commitment.

Basson MA, Wilson TJ, Legname GA, Sarner N, Tomlinson PD, Tybulewicz VL, Zamoyska R.

J Immunol. 2000 Sep 1;165(5):2444-50.

16.

Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells.

Grueter B, Petter M, Egawa T, Laule-Kilian K, Aldrian CJ, Wuerch A, Ludwig Y, Fukuyama H, Wardemann H, Waldschuetz R, Möröy T, Taniuchi I, Steimle V, Littman DR, Ehlers M.

J Immunol. 2005 Aug 1;175(3):1694-705. Erratum in: J Immunol. 2005 Nov 1;175(9):6238.

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Critical role for the common cytokine receptor gamma chain in intrathymic and peripheral T cell selection.

DiSanto JP, Guy-Grand D, Fisher A, Tarakhovsky A.

J Exp Med. 1996 Mar 1;183(3):1111-8.

19.

Impaired thymic selection in mice expressing altered levels of the SLP-76 adaptor protein.

Ramsey K, Luckashenak N, Koretzky GA, Clements JL.

J Leukoc Biol. 2008 Feb;83(2):419-29.

PMID:
17965338
20.

CD45 can act as a negative regulator for the transition from early to late CD4+ CD8+ thymocytes.

Sato T, Nunomura S, Sato C, Hozumi K, Kumagai Y, Nishimura T, Mak TW, Kishihara K, Habu S.

Int Immunol. 1999 Jan;11(1):89-97.

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