Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 102

1.

Structure-activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B.

McGinty RK, Köhn M, Chatterjee C, Chiang KP, Pratt MR, Muir TW.

ACS Chem Biol. 2009 Nov 20;4(11):958-68. doi: 10.1021/cb9002255.

2.

Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation.

McGinty RK, Kim J, Chatterjee C, Roeder RG, Muir TW.

Nature. 2008 Jun 5;453(7196):812-6. doi: 10.1038/nature06906.

3.

Evidence that ubiquitylated H2B corrals hDot1L on the nucleosomal surface to induce H3K79 methylation.

Zhou L, Holt MT, Ohashi N, Zhao A, Müller MM, Wang B, Muir TW.

Nat Commun. 2016 Feb 2;7:10589. doi: 10.1038/ncomms10589.

4.

Histone monoubiquitylation position determines specificity and direction of enzymatic cross-talk with histone methyltransferases Dot1L and PRC2.

Whitcomb SJ, Fierz B, McGinty RK, Holt M, Ito T, Muir TW, Allis CD.

J Biol Chem. 2012 Jul 6;287(28):23718-25. doi: 10.1074/jbc.M112.361824.

5.

Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin.

Holt MT, David Y, Pollock S, Tang Z, Jeon J, Kim J, Roeder RG, Muir TW.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10365-70. doi: 10.1073/pnas.1504483112.

6.

Effects of histone acetylation, ubiquitination and variants on nucleosome stability.

Li W, Nagaraja S, Delcuve GP, Hendzel MJ, Davie JR.

Biochem J. 1993 Dec 15;296 ( Pt 3):737-44.

7.

Stability of nucleosomes containing homogenously ubiquitylated H2A and H2B prepared using semisynthesis.

Fierz B, Kilic S, Hieb AR, Luger K, Muir TW.

J Am Chem Soc. 2012 Dec 5;134(48):19548-51. doi: 10.1021/ja308908p.

8.

Dot1L mediated histone H3 lysine79 methylation is essential to meiosis progression in mouse oocytes.

Wang X, Gao W, Ma X, Wang X, Song C, Huang X, Liu H.

Neuro Endocrinol Lett. 2014;35(6):523-30.

PMID:
25433842
9.

The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure.

Jones B, Su H, Bhat A, Lei H, Bajko J, Hevi S, Baltus GA, Kadam S, Zhai H, Valdez R, Gonzalo S, Zhang Y, Li E, Chen T.

PLoS Genet. 2008 Sep 12;4(9):e1000190. doi: 10.1371/journal.pgen.1000190.

10.

Methylation of H3 K4 and K79 is not strictly dependent on H2B K123 ubiquitylation.

Foster ER, Downs JA.

J Cell Biol. 2009 Mar 9;184(5):631-8. doi: 10.1083/jcb.200812088.

11.

Trypanosome H2Bv replaces H2B in nucleosomes enriched for H3 K4 and K76 trimethylation.

Mandava V, Janzen CJ, Cross GA.

Biochem Biophys Res Commun. 2008 Apr 18;368(4):846-51. doi: 10.1016/j.bbrc.2008.01.144.

12.

Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo.

Vlaming H, van Welsem T, de Graaf EL, Ontoso D, Altelaar AF, San-Segundo PA, Heck AJ, van Leeuwen F.

EMBO Rep. 2014 Oct;15(10):1077-84. doi: 10.15252/embr.201438793. Erratum in: EMBO Rep. 2014 Nov;15(11):1220-1.

13.

Histone H2B ubiquitination and beyond: Regulation of nucleosome stability, chromatin dynamics and the trans-histone H3 methylation.

Chandrasekharan MB, Huang F, Sun ZW.

Epigenetics. 2010 Aug 16;5(6):460-8. doi: 10.4161/epi.5.6.12314. Review.

14.

The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure.

Lu X, Simon MD, Chodaparambil JV, Hansen JC, Shokat KM, Luger K.

Nat Struct Mol Biol. 2008 Oct;15(10):1122-4. doi: 10.1038/nsmb.1489.

15.

Traceless semisynthesis of a set of histone 3 species bearing specific lysine methylation marks.

Chen Z, Grzybowski AT, Ruthenburg AJ.

Chembiochem. 2014 Sep 22;15(14):2071-5. doi: 10.1002/cbic.201402313.

16.

The elusive structural role of ubiquitinated histones.

Moore SC, Jason L, Ausió J.

Biochem Cell Biol. 2002;80(3):311-9. Review.

PMID:
12123284
17.

Deficiency of H3K79 histone methyltransferase Dot1-like protein (DOT1L) inhibits cell proliferation.

Kim W, Kim R, Park G, Park JW, Kim JE.

J Biol Chem. 2012 Feb 17;287(8):5588-99. doi: 10.1074/jbc.M111.328138.

18.

Histone methyltransferase Dot1L plays a role in postembryonic development in Xenopus tropicalis.

Wen L, Fu L, Guo X, Chen Y, Shi YB.

FASEB J. 2015 Feb;29(2):385-93. doi: 10.1096/fj.14-252171.

19.

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.

Steger DJ, Lefterova MI, Ying L, Stonestrom AJ, Schupp M, Zhuo D, Vakoc AL, Kim JE, Chen J, Lazar MA, Blobel GA, Vakoc CR.

Mol Cell Biol. 2008 Apr;28(8):2825-39. doi: 10.1128/MCB.02076-07.

20.

The role of histone H2A and H2B post-translational modifications in transcription: a genomic perspective.

Wyrick JJ, Parra MA.

Biochim Biophys Acta. 2009 Jan;1789(1):37-44. doi: 10.1016/j.bbagrm.2008.07.001. Review.

PMID:
18675384
Items per page

Supplemental Content

Support Center