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Items: 1 to 20 of 351

1.

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response.

Marteijn JA, Bekker-Jensen S, Mailand N, Lans H, Schwertman P, Gourdin AM, Dantuma NP, Lukas J, Vermeulen W.

J Cell Biol. 2009 Sep 21;186(6):835-47. doi: 10.1083/jcb.200902150.

2.

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase.

Kolas NK, Chapman JR, Nakada S, Ylanko J, Chahwan R, Sweeney FD, Panier S, Mendez M, Wildenhain J, Thomson TM, Pelletier L, Jackson SP, Durocher D.

Science. 2007 Dec 7;318(5856):1637-40. Epub 2007 Nov 15.

3.

DNA damage signaling in response to double-strand breaks during mitosis.

Giunta S, Belotserkovskaya R, Jackson SP.

J Cell Biol. 2010 Jul 26;190(2):197-207. doi: 10.1083/jcb.200911156.

4.

Nucleotide excision repair-dependent DNA double-strand break formation and ATM signaling activation in mammalian quiescent cells.

Wakasugi M, Sasaki T, Matsumoto M, Nagaoka M, Inoue K, Inobe M, Horibata K, Tanaka K, Matsunaga T.

J Biol Chem. 2014 Oct 10;289(41):28730-7. doi: 10.1074/jbc.M114.589747. Epub 2014 Aug 27.

5.

RNF8- and Ube2S-Dependent Ubiquitin Lysine 11-Linkage Modification in Response to DNA Damage.

Paul A, Wang B.

Mol Cell. 2017 May 18;66(4):458-472.e5. doi: 10.1016/j.molcel.2017.04.013.

PMID:
28525740
6.

Polo-like kinase 1 inhibits DNA damage response during mitosis.

Benada J, Burdová K, Lidak T, von Morgen P, Macurek L.

Cell Cycle. 2015;14(2):219-31. doi: 10.4161/15384101.2014.977067.

7.

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.

Mailand N, Bekker-Jensen S, Faustrup H, Melander F, Bartek J, Lukas C, Lukas J.

Cell. 2007 Nov 30;131(5):887-900. Epub 2007 Nov 20.

8.

RNF8-dependent and RNF8-independent regulation of 53BP1 in response to DNA damage.

Sakasai R, Tibbetts R.

J Biol Chem. 2008 May 16;283(20):13549-55. doi: 10.1074/jbc.M710197200. Epub 2008 Mar 12.

9.

MDC1 is a mediator of the mammalian DNA damage checkpoint.

Stewart GS, Wang B, Bignell CR, Taylor AM, Elledge SJ.

Nature. 2003 Feb 27;421(6926):961-6.

PMID:
12607005
10.

ATDC (Ataxia Telangiectasia Group D Complementing) Promotes Radioresistance through an Interaction with the RNF8 Ubiquitin Ligase.

Yang H, Palmbos PL, Wang L, Kim EH, Ney GM, Liu C, Prasad J, Misek DE, Yu X, Ljungman M, Simeone DM.

J Biol Chem. 2015 Nov 6;290(45):27146-57. doi: 10.1074/jbc.M115.665489. Epub 2015 Sep 17.

11.

Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair.

Moon SH, Lin L, Zhang X, Nguyen TA, Darlington Y, Waldman AS, Lu X, Donehower LA.

J Biol Chem. 2010 Apr 23;285(17):12935-47. doi: 10.1074/jbc.M109.071696. Epub 2010 Jan 29.

12.

ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks.

Lee KY, Im JS, Shibata E, Dutta A.

Mol Cell. 2017 Oct 5;68(1):61-75.e5. doi: 10.1016/j.molcel.2017.08.021. Epub 2017 Sep 21.

PMID:
28943310
13.

Replication independent ATR signalling leads to G2/M arrest requiring Nbs1, 53BP1 and MDC1.

Stiff T, Cerosaletti K, Concannon P, O'Driscoll M, Jeggo PA.

Hum Mol Genet. 2008 Oct 15;17(20):3247-53. doi: 10.1093/hmg/ddn220. Epub 2008 Jul 28.

14.

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.

Thorslund T, Ripplinger A, Hoffmann S, Wild T, Uckelmann M, Villumsen B, Narita T, Sixma TK, Choudhary C, Bekker-Jensen S, Mailand N.

Nature. 2015 Nov 19;527(7578):389-93. doi: 10.1038/nature15401. Epub 2015 Oct 21.

PMID:
26503038
15.

RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1.

Nakada S, Yonamine RM, Matsuo K.

Cancer Res. 2012 Oct 1;72(19):4974-83. doi: 10.1158/0008-5472.CAN-12-1057. Epub 2012 Aug 3.

16.

Three-dimensional imaging reveals the spatial separation of γH2AX-MDC1-53BP1 and RNF8-RNF168-BRCA1-A complexes at ionizing radiation-induced foci.

Mok MT, Henderson BR.

Radiother Oncol. 2012 Jun;103(3):415-20. doi: 10.1016/j.radonc.2012.04.009. Epub 2012 May 24.

PMID:
22633816
17.

BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair.

Ginjala V, Nacerddine K, Kulkarni A, Oza J, Hill SJ, Yao M, Citterio E, van Lohuizen M, Ganesan S.

Mol Cell Biol. 2011 May;31(10):1972-82. doi: 10.1128/MCB.00981-10. Epub 2011 Mar 7.

18.

DNA-damage response and repair activities at uncapped telomeres depend on RNF8.

Peuscher MH, Jacobs JJ.

Nat Cell Biol. 2011 Aug 21;13(9):1139-45. doi: 10.1038/ncb2326.

PMID:
21857671
19.

UV-induced histone H2AX phosphorylation and DNA damage related proteins accumulate and persist in nucleotide excision repair-deficient XP-B cells.

Oh KS, Bustin M, Mazur SJ, Appella E, Kraemer KH.

DNA Repair (Amst). 2011 Jan 2;10(1):5-15. doi: 10.1016/j.dnarep.2010.09.004. Epub 2010 Oct 13.

20.

MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1.

Li X, Corsa CA, Pan PW, Wu L, Ferguson D, Yu X, Min J, Dou Y.

Mol Cell Biol. 2010 Nov;30(22):5335-47. doi: 10.1128/MCB.00350-10. Epub 2010 Sep 13.

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