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Items: 1 to 20 of 128

1.

Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor.

Moens AL, Leyton-Mange JS, Niu X, Yang R, Cingolani O, Arkenbout EK, Champion HC, Bedja D, Gabrielson KL, Chen J, Xia Y, Hale AB, Channon KM, Halushka MK, Barker N, Wuyts FL, Kaminski PM, Wolin MS, Kass DA, Barouch LA.

J Mol Cell Cardiol. 2009 Nov;47(5):576-85. doi: 10.1016/j.yjmcc.2009.06.005. Epub 2009 Sep 18.

2.

Cardioprotective effect of beta-3 adrenergic receptor agonism: role of neuronal nitric oxide synthase.

Niu X, Watts VL, Cingolani OH, Sivakumaran V, Leyton-Mange JS, Ellis CL, Miller KL, Vandegaer K, Bedja D, Gabrielson KL, Paolocci N, Kass DA, Barouch LA.

J Am Coll Cardiol. 2012 May 29;59(22):1979-87. doi: 10.1016/j.jacc.2011.12.046. Erratum in: J Am Coll Cardiol. 2012 Jul 31;60(5):481.

3.

Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load.

Takimoto E, Champion HC, Li M, Ren S, Rodriguez ER, Tavazzi B, Lazzarino G, Paolocci N, Gabrielson KL, Wang Y, Kass DA.

J Clin Invest. 2005 May;115(5):1221-31. Epub 2005 Apr 14.

4.

Aerobic exercise protects against pressure overload-induced cardiac dysfunction and hypertrophy via β3-AR-nNOS-NO activation.

Wang B, Xu M, Li W, Li X, Zheng Q, Niu X.

PLoS One. 2017 Jun 16;12(6):e0179648. doi: 10.1371/journal.pone.0179648. eCollection 2017.

5.

Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy.

Moens AL, Takimoto E, Tocchetti CG, Chakir K, Bedja D, Cormaci G, Ketner EA, Majmudar M, Gabrielson K, Halushka MK, Mitchell JB, Biswal S, Channon KM, Wolin MS, Alp NJ, Paolocci N, Champion HC, Kass DA.

Circulation. 2008 May 20;117(20):2626-36. doi: 10.1161/CIRCULATIONAHA.107.737031. Epub 2008 May 12.

6.

Tetrahydrobiopterin Protects Against Hypertrophic Heart Disease Independent of Myocardial Nitric Oxide Synthase Coupling.

Hashimoto T, Sivakumaran V, Carnicer R, Zhu G, Hahn VS, Bedja D, Recalde A, Duglan D, Channon KM, Casadei B, Kass DA.

J Am Heart Assoc. 2016 Mar 21;5(3):e003208. doi: 10.1161/JAHA.116.003208.

7.

Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.

Belge C, Hammond J, Dubois-Deruy E, Manoury B, Hamelet J, Beauloye C, Markl A, Pouleur AC, Bertrand L, Esfahani H, Jnaoui K, Götz KR, Nikolaev VO, Vanderper A, Herijgers P, Lobysheva I, Iaccarino G, Hilfiker-Kleiner D, Tavernier G, Langin D, Dessy C, Balligand JL.

Circulation. 2014 Jan 28;129(4):451-62. doi: 10.1161/CIRCULATIONAHA.113.004940. Epub 2013 Nov 4.

8.

Sepiapterin prevents left ventricular hypertrophy and dilatory remodeling induced by pressure overload in rats.

Yoshioka K, Otani H, Shimazu T, Fujita M, Iwasaka T, Shiojima I.

Am J Physiol Heart Circ Physiol. 2015 Nov 15;309(10):H1782-91. doi: 10.1152/ajpheart.00417.2015. Epub 2015 Sep 25.

PMID:
26408540
9.

Bi-modal dose-dependent cardiac response to tetrahydrobiopterin in pressure-overload induced hypertrophy and heart failure.

Moens AL, Ketner EA, Takimoto E, Schmidt TS, O'Neill CA, Wolin MS, Alp NJ, Channon KM, Kass DA.

J Mol Cell Cardiol. 2011 Oct;51(4):564-9. doi: 10.1016/j.yjmcc.2011.05.017. Epub 2011 May 30.

10.

Anti-hypertrophic and anti-oxidant effect of beta3-adrenergic stimulation in myocytes requires differential neuronal NOS phosphorylation.

Watts VL, Sepulveda FM, Cingolani OH, Ho AS, Niu X, Kim R, Miller KL, Vandegaer K, Bedja D, Gabrielson KL, Rameau G, O'Rourke B, Kass DA, Barouch LA.

J Mol Cell Cardiol. 2013 Sep;62:8-17. doi: 10.1016/j.yjmcc.2013.04.025. Epub 2013 May 2.

11.

Cardiomyocyte-restricted restoration of nitric oxide synthase 3 attenuates left ventricular remodeling after chronic pressure overload.

Buys ES, Raher MJ, Blake SL, Neilan TG, Graveline AR, Passeri JJ, Llano M, Perez-Sanz TM, Ichinose F, Janssens S, Zapol WM, Picard MH, Bloch KD, Scherrer-Crosbie M.

Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H620-7. Epub 2007 Apr 6.

PMID:
17416602
12.

Lack of tissue inhibitor of metalloproteinases 2 leads to exacerbated left ventricular dysfunction and adverse extracellular matrix remodeling in response to biomechanical stress.

Kandalam V, Basu R, Moore L, Fan D, Wang X, Jaworski DM, Oudit GY, Kassiri Z.

Circulation. 2011 Nov 8;124(19):2094-105. doi: 10.1161/CIRCULATIONAHA.111.030338. Epub 2011 Oct 10.

13.

Normal and high eNOS levels are detrimental in both mild and severe cardiac pressure-overload.

van Deel ED, Octavia Y, de Boer M, Juni RP, Tempel D, van Haperen R, de Crom R, Moens AL, Merkus D, Duncker DJ.

J Mol Cell Cardiol. 2015 Nov;88:145-54. doi: 10.1016/j.yjmcc.2015.10.001. Epub 2015 Oct 3.

PMID:
26436984
14.

Protein kinase g iα inhibits pressure overload-induced cardiac remodeling and is required for the cardioprotective effect of sildenafil in vivo.

Blanton RM, Takimoto E, Lane AM, Aronovitz M, Piotrowski R, Karas RH, Kass DA, Mendelsohn ME.

J Am Heart Assoc. 2012 Oct;1(5):e003731. doi: 10.1161/JAHA.112.003731. Epub 2012 Oct 25.

15.

Pressure overload-induced LV hypertrophy and dysfunction in mice are exacerbated by congenital NOS3 deficiency.

Ichinose F, Bloch KD, Wu JC, Hataishi R, Aretz HT, Picard MH, Scherrer-Crosbie M.

Am J Physiol Heart Circ Physiol. 2004 Mar;286(3):H1070-5. Epub 2003 Nov 26.

PMID:
14644766
16.

Nitric oxide synthase 3 deficiency limits adverse ventricular remodeling after pressure overload in insulin resistance.

Kurtz B, Thibault HB, Raher MJ, Popovich JR, Cawley S, Atochin DN, Hayton S, Shakartzi HR, Huang PL, Bloch KD, Buys E, Scherrer-Crosbie M.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H2093-101. doi: 10.1152/ajpheart.00744.2010. Epub 2011 Aug 19.

17.

Concentric left ventricular remodeling in endothelial nitric oxide synthase knockout mice by chronic pressure overload.

Ruetten H, Dimmeler S, Gehring D, Ihling C, Zeiher AM.

Cardiovasc Res. 2005 Jun 1;66(3):444-53. Epub 2005 Feb 24.

PMID:
15914109
18.

The β3 Adrenergic Receptor Agonist BRL37344 Exacerbates Atrial Structural Remodeling Through iNOS Uncoupling in Canine Models of Atrial Fibrillation.

Wang X, Wang R, Liu G, Dong J, Zhao G, Tian J, Sun J, Jia X, Wei L, Wang Y, Li W.

Cell Physiol Biochem. 2016;38(2):514-30. doi: 10.1159/000438647. Epub 2016 Feb 1.

19.

Effects of adiponectin deficiency on structural and metabolic remodeling in mice subjected to pressure overload.

O'Shea KM, Chess DJ, Khairallah RJ, Rastogi S, Hecker PA, Sabbah HN, Walsh K, Stanley WC.

Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H1639-45. doi: 10.1152/ajpheart.00957.2009. Epub 2010 Mar 26.

20.

Role of inducible nitric oxide synthase in cardiac function and remodeling in mice with heart failure due to myocardial infarction.

Liu YH, Carretero OA, Cingolani OH, Liao TD, Sun Y, Xu J, Li LY, Pagano PJ, Yang JJ, Yang XP.

Am J Physiol Heart Circ Physiol. 2005 Dec;289(6):H2616-23. Epub 2005 Jul 29.

PMID:
16055518

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